Abstract: A vehicle shaft has a rigid intermediate portion with a shaft journal welded to each of the two ends of the shaft portion. The shaft journal and/or the intermediate portion are/is provided with a material thickness reduction within a distance a from the contact surfaces which is less than substantially half the material thickness at the contact surfaces, in order to guide the force flow thorough the weld seam. During manufacture of such vehicle shafts, the mutually abutting contact surfaces are laser-welded to form a weld seam which can fully penetrate the material of the shaft journals and the intermediate portion respectively, whereby the concentricity and parallelism of the two journals will be within predetermined dimensional tolerances after the welding and cooling of the material. The arrangement has an induction heater which surrounds the shaft journal and is movable axially so that, after completion of heating, it moves to free the shaft journals welded to the shaft portion.

Abstract: A vehicle shaft has a rigid intermediate portion with a shaft journal welded to each of the two ends of the shaft portion. The shaft journal and/or the intermediate portion are/is provided with a material thickness reduction within a distance a from the contact surfaces which is less than substantially half the material thickness at the contact surfaces, in order to guide the force flow thorough the weld seam. During manufacture of such vehicle shafts, the mutually abutting contact surfaces are laser-welded to form a weld seam which can fully penetrate the material of the shaft journals and the intermediate portion respectively, whereby the concentricity and parallelism of the two journals will be within predetermined dimensional tolerances after the welding and cooling of the material. The arrangement has an induction heater which surrounds the shaft journal and is movable axially so that, after completion of heating, it moves to free the shaft journals welded to the shaft portion.

Abstract: The present invention relates to a method of predicting the therapeutic response of a drug against a malignant tumour in a human patient, using a sample of a fine needle aspirate of the tumour from the patient. The method comprises the steps of identifying and estimating in the sample the number of cells belonging to one class of cells in relation to other cells in the sample, and comparing the estimation with a previously made analysis demonstrating correlation between the number of cells and parameters of the therapeutic response of the drug directed towards the tumour in human patients, the results of the comparison being indicative of the therapeutic response of the drug in human patient.