Abstract: Systems and methods for cryoablation. One example system includes an interior portion, an exterior portion and a treatment element. The system includes a first loop in the interior portion of the system, the first loop having a first controller, at least one valve, and a first sensor; a second loop in the interior portion of the system, the second loop having a second controller, and at least one valve, and a second sensor; a pressurized coolant supply in fluid communication with the first loop and the second loop; and a temperature sensor disposed on the exterior portion of the system, the temperature sensor being configured to monitor the temperature on the exterior portion of the system.

Abstract: A device, system, and method for performing a variety of treatment procedures safely with a single treatment device. For example, a system is provided that includes a treatment device with a highly conformable balloon that is inflated at a constant pressure and that remains “soft” during use, which enhances balloon-tissue contact, treatment efficacy, and patient safety. In one embodiment, a system for ablating tissue comprises: a treatment device including a highly conformable balloon; a control unit including a fluid supply reservoir in fluid communication with the highly conformable balloon, the control unit being configured to deliver fluid from the fluid supply reservoir to the highly conformable balloon such that the highly conformable balloon is maintained at a balloon pressure of between 0.2 psig and 3.0 psig.

Abstract: A method and system for controlling flow of refrigerant through a medical device are disclosed. According to one aspect, a system for delivering refrigerant to an expansion cavity portion of the medical device comprises a first path and a second path in communication with the expansion cavity portion. The system also includes a first PID controller in communication with a first proportional valve in the first path, the first PID controller being configured to operate the first proportional valve based on a pressure measurement in the first path; and a second PID controller in communication with a second proportional valve in the second path, the second controller being configured to operate the second proportional valve based on a pressure measurement in the second path or in the expansion cavity portion.

Abstract: A method and system for feedback control for cryo-mapping and cryoablation are disclosed. According to one aspect, a cryo-mapping and cryoablation control system includes a first control device configured to receive a target parameter value and a measured output parameter and to output an injection pressure target signal based on a first difference between the target parameter value and the measured output parameter. The system also includes a second control device configured to receive the injection pressure target signal and to output a valve control signal, the valve control signal being used to set a position of an injection pressure valve. The first control device is configured to determine a value of the injection pressure target signal to drive the first difference toward zero.

Abstract: A device, system, and method for performing a variety of treatment procedures safely with a single treatment device. For example, a system is provided that includes a treatment device with a highly conformable balloon that is inflated at a constant pressure and that remains “soft” during use, which enhances balloon-tissue contact, treatment efficacy, and patient safety. In one embodiment, a system for ablating tissue comprises: a treatment device including a highly conformable balloon; a control unit including a fluid supply reservoir in fluid communication with the highly conformable balloon, the control unit being configured to deliver fluid from the fluid supply reservoir to the highly conformable balloon such that the highly conformable balloon is maintained at a balloon pressure of between 0.2 psig and 3.0 psig.

Abstract: A device, system, and method for performing a variety of treatment procedures safely with a single treatment device. For example, a system is provided that includes a treatment device with a highly conformable balloon that is inflated at a constant pressure and that remains “soft” during use, which enhances balloon-tissue contact, treatment efficacy, and patient safety. In one embodiment, a system for ablating tissue comprises: a treatment device including a highly conformable balloon; a control unit including a fluid supply reservoir in fluid communication with the highly conformable balloon, the control unit being configured to deliver fluid from the fluid supply reservoir to the highly conformable balloon such that the highly conformable balloon is maintained at a balloon pressure of between 0.2 psig and 3.0 psig.

Abstract: A device, system, and method for performing a variety of treatment procedures safely with a single treatment device. For example, a system is provided that includes a treatment device with a highly conformable balloon that is inflated at a constant pressure and that remains “soft” during use, which enhances balloon-tissue contact, treatment efficacy, and patient safety. In one embodiment, a system for ablating tissue comprises: a treatment device including a highly conformable balloon; a control unit including a fluid supply reservoir in fluid communication with the highly conformable balloon, the control unit being configured to deliver fluid from the fluid supply reservoir to the highly conformable balloon such that the highly conformable balloon is maintained at a balloon pressure of between 0.2 psig and 3.0 psig.

Abstract: A method for purging a cryotreatment system, in particular, for clearing moisture and thus preventing ice blockages within a fluid flow path that may be formed when moisture pockets within the fluid flow path of the system are encountered by a first injection of refrigerant at the beginning of a cryotreatment procedure. The method may include injecting refrigerant from a refrigerant source into a fluid delivery conduit at a preselected pressure for a first period of time, the refrigerant flowing from the fluid delivery conduit through a fluid injection element and into a fluid recovery conduit, and evacuating refrigerant from the fluid recovery conduit by vacuum pressure generated by the vacuum pump for a second period of time. This method may be repeated for a plurality of cycles.

Abstract: A method for purging a cryotreatment system, in particular, for clearing moisture and thus preventing ice blockages within a fluid flow path that may be formed when moisture pockets within the fluid flow path of the system are encountered by a first injection of refrigerant at the beginning of a cryotreatment procedure. The method may include injecting refrigerant from a refrigerant source into a fluid delivery conduit at a preselected pressure for a first period of time, the refrigerant flowing from the fluid delivery conduit through a fluid injection element and into a fluid recovery conduit, and evacuating refrigerant from the fluid recovery conduit by vacuum pressure generated by the vacuum pump for a second period of time. This method may be repeated for a plurality of cycles.