Patents by Inventor Bertram Jacobs

Bertram Jacobs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ORAL BOTANICAL COMPOSITION
    Publication number: 20240131104
    Abstract: This invention is directed to oral botanical compositions comprising plant extracts, methods of preparing the same, and methods of using the same for treating an infection.
    Type: Application
    Filed: February 11, 2022
    Publication date: April 25, 2024
    Inventors: Jeffrey Olaf Langland, Bertram Jacobs
  • HIV vaccination compositions comprising vaccinia VLPS and plant-produced VLPS presenting HIV antigens
    Patent number: 11918642
    Abstract: Disclosed are compositions for generating an immune response against human immunodeficiency virus (HIV) and their methods of uses.
    Type: Grant
    Filed: September 29, 2021
    Date of Patent: March 5, 2024
    Assignee: Arizona Board of Regents on Behalf of Arizona State University
    Inventors: Tsafrir S. Leket-Mor, Bertram Jacobs, Lydia Meador, Karen Kibler
  • MODIFIED IMMUNIZATION VECTORS
    Publication number: 20230009041
    Abstract: The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
    Type: Application
    Filed: April 28, 2022
    Publication date: January 12, 2023
    Applicants: Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of, Consejo Superior De Investigaciones Cientificas, IPPOX Foundation
    Inventors: Giuseppe Pantaleo, Thierry Calandra, Alexandre Harari, Thierry Roger, Mariano Esteban, Bertram Jacobs, Karen Kibler, Cornelius Melief, Rafick-Pierre Sekaly, Elias Haddad, James Tartaglia
  • Pharmaceutical compositions comprising caffeic acid chelates
    Patent number: 11458203
    Abstract: The present disclosure relates to pharmaceutical compositions comprising caffeic acid chelates, kits, and methods for using such compounds and pharmaceutical compositions.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: October 4, 2022
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Thomas Cahill, Jeffrey Langland, Bertram Jacobs, Carl Wagner, Guillermo Ruiz
  • Modified immunization vectors
    Patent number: 11345928
    Abstract: The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: May 31, 2022
    Assignees: Arizona Board of Regents, Conseju Superior De Investigaciones Cientificas, IPPOX Foundation
    Inventors: Giuseppe Pantaleo, Thierry Calandra, Alexandre Harari, Thierry Roger, Mariano Esteban, Bertram Jacobs, Karen Kibler, Cornelius Melief, Rafick-Pierre Sekaly, Elias El Haddad, James Tartaglia
  • HIV VACCINATION COMPOSITIONS
    Publication number: 20220088178
    Abstract: Disclosed are compositions for generating an immune response against human immunodeficiency virus (HIV) and their methods of uses.
    Type: Application
    Filed: September 29, 2021
    Publication date: March 24, 2022
    Inventors: Tsafrir S. Leket-Mor, Bertram Jacobs, Lydia Meador, Karen Kibler
  • METHOD AND COMPOSITIONS FOR THE USE OF BOTANICAL EXTRACTS IN THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20220062365
    Abstract: The present disclosure relates generally to the preparation and use of certain botanical extracts and therapeutic compositions for the treatment of viral infections, cancer, pain, itch, and inflammation. The present disclosure generally relates to antiviral compositions, and more specifically to the preparation of botanical extracts and their use in the treatment of viral infections, cancer, pain associated conditions.
    Type: Application
    Filed: October 19, 2020
    Publication date: March 3, 2022
    Inventors: Jeffrey Langland, Karen Denzler, Robert Waters, Bertram Jacobs
  • METHOD AND COMPOSITIONS FOR THE USE OF BOTANICAL EXTRACTS IN THE TREATMENT OF VIRAL INFECTIONS
    Publication number: 20210275620
    Abstract: The present disclosure relates generally to the preparation and use of certain botanical extracts and therapeutic compositions for the treatment of viral infections, cancer, pain, itch, and inflammation. The present disclosure generally relates to antiviral compositions, and more specifically to the preparation of botanical extracts and their use in the treatment of viral infections, cancer, pain associated conditions.
    Type: Application
    Filed: January 15, 2021
    Publication date: September 9, 2021
    Inventors: Jeffrey Langland, Karen Denzler, Robert Waters, Bertram Jacobs
  • Method for the use of botanical extracts in the treatment of viral infections
    Patent number: 10842838
    Abstract: The present disclosure relates generally methods of preparation and use of certain botanical extracts for the treatment of viral infections.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: November 24, 2020
    Assignee: Aviratek Biomedical Solutions, LLC
    Inventors: Jeffrey Langland, Karen Denzler, Robert Waters, Bertram Jacobs
  • Oncolytic vaccinia virus mutants and using same for cancer treatment
    Patent number: 10842835
    Abstract: Methods utilizing vaccinia virus with mutations in E3L to infect and cause lysis of cancer cells with less than normal protein levels of RIP3 and/or DAI. Further, the disclosed vaccinia viruses with mutations in E3L cannot replicate well in cells with normal expression or upregulation of RIP3, DAI, and/or MLKL.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: November 24, 2020
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Bertram Jacobs, Heather Koehler, William Arndt, Karen Kibler, Kelly Trainor, Chandra Mitnik, Jeffrey Langland
  • PHARMACEUTICAL COMPOSITIONS COMPRISING CAFFEIC ACID CHELATES
    Publication number: 20200171331
    Abstract: The present disclosure relates to pharmaceutical compositions comprising caffeic acid chelates, kits, and methods for using such compounds and pharmaceutical compositions.
    Type: Application
    Filed: May 8, 2018
    Publication date: June 4, 2020
    Inventors: Thomas Cahill, Jeffrey Langland, Bertram Jacobs, Carl Wagner, Guillermo Ruiz
  • MODIFIED IMMUNIZATION VECTORS
    Publication number: 20200172926
    Abstract: The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
    Type: Application
    Filed: July 17, 2019
    Publication date: June 4, 2020
    Applicants: Arizona Board of Regents, a body corporate of the State of Arizona acting for and on behalf of Arizo, Consejo Superior De Investigaciones Cientificas, IPPOX Foundation
    Inventors: Giuseppe Pantaleo, Thierry Calandra, Alexandre Harari, Thierry Roger, Mario Esteban, Bertram Jacobs, Karen Kibler, Cornelius Melief, Rafick-Pierre Sekaly, Elias El Haddad, James Tartaglia
  • HIV VACCINATION COMPOSITIONS
    Publication number: 20190328864
    Abstract: Disclosed are compositions for generating an immune response against human immunodeficiency virus (HIV) and their methods of uses.
    Type: Application
    Filed: April 27, 2019
    Publication date: October 31, 2019
    Inventors: Tsafrir Mor, Bertram Jacobs, Lydia Meador, Karen Kibler
  • Modified immunization vectors
    Patent number: 10370679
    Abstract: The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
    Type: Grant
    Filed: October 10, 2016
    Date of Patent: August 6, 2019
    Assignees: ARIZONA BOARD OF REGENTS, a body corporate of the State of Arizona acting for and on behalf of Ariz, CONSEJO SUPERIOR DE INVESTGACIONES CIENTRIFICAS, IPPOX FOUNDATION
    Inventors: Giuseppe Pantaleo, Thierry Calandra, Alexandre Harari, Thierry Roger, Mariano Esteban, Bertram Jacobs, Karen Kibler, Cornelius Melief, Rafick-Pierre Sekaly, Elias El Haddad, James Tartaglia
  • METHOD AND COMPOSITIONS FOR THE USE OF BOTANICAL EXTRACTS IN THE TREATMENT OF VIRAL INFECTIONS, CANCER, PAIN, ITCH, AND INFLAMMATION
    Publication number: 20190231836
    Abstract: The present disclosure relates generally to the preparation and use of certain botanical extracts and therapeutic compositions for the treatment of viral infections, cancer, pain, itch, and inflammation. The present disclosure generally relates to antiviral compositions, and more specifically to the preparation of botanical extracts and their use in the treatment of viral infections, cancer, pain associated conditions.
    Type: Application
    Filed: January 30, 2019
    Publication date: August 1, 2019
    Inventors: Jeffrey Langland, Karen Denzler, Robert Waters, Bertram Jacobs
  • ONCOLYTIC VACCINIA VIRUS MUTANTS AND USING SAME FOR CANCER TREATMENT
    Publication number: 20190183947
    Abstract: Methods utilizing vaccinia virus with mutations in E3L to infect and cause lysis of cancer cells with less than normal protein levels of RIP3 and/or DAI. Further, the disclosed vaccinia viruses with mutations in E3L cannot replicate well in cells with normal expression or upregulation of RIP3, DAI, and/or MLKL.
    Type: Application
    Filed: May 25, 2017
    Publication date: June 20, 2019
    Inventors: Bertram Jacobs, Heather Koehler, William Arndt, Karen Kibler, Kelly Trainor, Chandra Mitnik, Jeffrey Langland
  • Methods of using extracts of melissa officinalis against filoviruses
    Patent number: 10293012
    Abstract: The present disclosure relates to methods of using Melissa officinalis extracts in inhibiting viral replication of a filovirus and in treating or preventing a filovirus infection.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: May 21, 2019
    Assignee: Arizona Board of Regents on behalf of Arizona State University
    Inventors: Jeffrey Langland, Bertram Jacobs, Karen Denzler
  • METHODS OF USING EXTRACTS OF MELISSA OFFICINALIS AGAINST FILOVIRUSES
    Publication number: 20180318373
    Abstract: The present disclosure relates to methods of using Melissa officinalis extracts in inhibiting viral replication of a filovirus and in treating or preventing a filovirus infection.
    Type: Application
    Filed: May 3, 2018
    Publication date: November 8, 2018
    Inventors: Jeffrey Langland, Bertram Jacobs, Karen Denzler
  • METHOD AND COMPOSITIONS FOR THE USE OF BOTANICAL EXTRACTS IN THE TREATMENT OF VIRAL INFECTIONS, CANCER, PAIN, ITCH, AND INFLAMMATION
    Publication number: 20180200320
    Abstract: The present disclosure relates generally to the preparation and use of certain botanical extracts and therapeutic compositions for the treatment of viral infections, cancer, pain, itch, and inflammation. The present disclosure generally relates to antiviral compositions, and more specifically to the preparation of botanical extracts and their use in the treatment of viral infections, cancer, pain associated conditions.
    Type: Application
    Filed: November 21, 2013
    Publication date: July 19, 2018
    Inventors: Jeffrey LANGLAND, Karen DENZLER, Bertram JACOBS, Robert F. WATERS
  • Modified Immunization Vectors
    Publication number: 20170246280
    Abstract: The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
    Type: Application
    Filed: October 10, 2016
    Publication date: August 31, 2017
    Inventors: Giuseppe Pantaleo, Thierry Calandra, Alexandre Harari, Thierry Roger, Mario Esteban, Bertram Jacobs, Karen Kibler, Cornelius Melief, Rafick-Pierre Sekaly, Elias Haddad, James Tartaglia