Patents by Inventor Bertrand M. C. Plouvier

Bertrand M. C. Plouvier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF
    Publication number: 20110207730
    Abstract: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
    Type: Application
    Filed: December 16, 2010
    Publication date: August 25, 2011
    Applicant: Cardiome Pharma Corp.
    Inventors: Allen I. Bain, Gregory N. Beatch, Cindy J. Longley, Bertrand M.C. Plouvier, Tao Sheng, Michael J.A. Walker, Richard A. Wall, Sandro L. Yong, Jeff Jiqun Zhu, Alexander B. Zolotoy
  • Prodrugs of ion channel modulating compounds and uses thereof
    Patent number: 7977373
    Abstract: Prodrugs of ion channeling modulating compounds, including, for example, prodrugs of the ion channel modulating compound of the following formula: are described herein, as well as methods of making and using such prodrugs and pharmaceutical compositions containing such prodrugs.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: July 12, 2011
    Assignee: Cardiome Pharma Corp.
    Inventors: Lewis Siu Leung Choi, Doug Ta Hung Chou, Allen W. Davidoff, Adewale Eniade, Bertrand M. C. Plouvier
  • Ion channel modulating compounds and uses thereof
    Patent number: 7875611
    Abstract: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
    Type: Grant
    Filed: April 15, 2009
    Date of Patent: January 25, 2011
    Assignee: Cardiome Pharma Corp.
    Inventors: Allen I. Bain, Gregory N. Beatch, Cindy J. Longley, Bertrand M. C. Plouvier, Tao Sheng, Michael J. A. Walker, Richard A. Wall, Sandro L. Yong, Jeff Jiqun Zhu, Alexander B. Zolotoy
  • AMINOCYCLOHEXYL ETHER COMPOUNDS AND USES THEREOF
    Publication number: 20110004006
    Abstract: Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
    Type: Application
    Filed: July 9, 2010
    Publication date: January 6, 2011
    Applicant: CARDIOME PHARMA CORP.
    Inventors: Grace Jung, Bertrand M. C. Plouvier, Yuzhong Liu, Jeff Jiqun Zhu, Tao Sheng, Anthony G. M. Barrett, Lewis Siu Leung Choi, Doug Ta Hung Chou
  • PEGYLATED ION CHANNEL MODULATING COMPOUNDS
    Publication number: 20100273724
    Abstract: This invention is directed to PEGlyated derivatives, drug conjugates and isotopic derivatives of certain ion channel modulating compounds.
    Type: Application
    Filed: July 7, 2010
    Publication date: October 28, 2010
    Applicant: CARDIOME PHARMA CORP.
    Inventors: Elizabeth L. S. Cheu, Lewis Siu Leung Choi, Doug Ta Hung Chou, Allen W. Davidoff, Alan M. Ezrin, Grace Jung, Bertrand M.C. Plouvier, Aregahegn S. Yifru
  • Drug conjugates of ion channel modulating compounds
    Patent number: 7786119
    Abstract: This invention is directed to drug conjugates of certain ion channel modulating compounds having the following formula: wherein A, X, R1, R2, R3, R4, R5, LB, L and DM are defined herein, including isolated enantiomeric and diastereomeric isomers thereof, and mixtures thereof. Pharmaceutical compositions and methods of use are also disclosed.
    Type: Grant
    Filed: March 31, 2005
    Date of Patent: August 31, 2010
    Assignee: Cardiome Pharma Corp.
    Inventors: Elizabeth L. S. Cheu, Lewis Siu Leung Choi, Doug Ta Hung Chou, Allen W. Davidoff, Alan M. Ezrin, Grace Jung, Bertrand M. C. Plouvier, Aregahegn S. Yifru
  • SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS
    Publication number: 20100217014
    Abstract: This invention is directed to stereoselective synthesis of compounds of formula (I) or formula (II): or a pharmaceutically acceptable salt, ester, amide, complex, chelate, clathrate, solvate, polymorph, stereoisomer, metabolite or prodrug thereof; wherein R3, R4 and R5 are defined herein. Compounds of formula (I) and formula (II) are known to be useful in treating arrhythmias.
    Type: Application
    Filed: February 19, 2010
    Publication date: August 26, 2010
    Applicant: CARDIOME PHARMA CORP.
    Inventors: Grace Jung, James Gee Ken Yee, Doug Ta Hung Chou, Bertrand M. C. Plouvier
  • Aminocyclohexyl ether compounds and uses thereof
    Patent number: 7767830
    Abstract: Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: August 3, 2010
    Assignee: Cardiome Pharma Corp.
    Inventors: Grace Jung, Bertrand M. C. Plouvier, Yuzhong Liu, Jeff Jiqun Zhu, Tao Sheng, Anthony G. M. Barrett, Lewis Siu Leung Choi, Doug Ta Hung Chou
  • Synthetic processes for the preparation of aminocyclohexyl ether compounds
    Patent number: 7754897
    Abstract: This invention is directed to stereoselective synthesis of compounds of formula (I) or formula (II): or a pharmaceutically acceptable salt, ester, amide, complex, chelate, clathrate, solvate, polymorph, stereoisomer, metabolite or prodrug thereof; wherein R3, R4 and R5 are defined herein. Compounds of formula (I) and formula (II) are known to be useful in treating arrhythmias.
    Type: Grant
    Filed: June 15, 2006
    Date of Patent: July 13, 2010
    Assignee: Cardiome Pharma Corp.
    Inventors: Grace Jung, James Gee Ken Yee, Doug Ta Hung Chou, Bertrand M. C. Plouvier
  • SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS
    Publication number: 20100152464
    Abstract: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.
    Type: Application
    Filed: November 18, 2005
    Publication date: June 17, 2010
    Applicant: CARDIOME PHARMA CORP.
    Inventors: Bertrand M. C. Plouvier, Doug Ta Hung Chou, Grace Jung, Lewis Siu Leung Choi, Tao Sheng, Anthony G. M. Barrett, Marco S. Passafaro, Martin Kurz, Daniel Moeckli, Pirmin Ulmann, Alfred Hedinger
  • DEUTERATED AMINOCYCLOHEXYL ETHER COMPOUNDS AND PROCESSES FOR PREPARING SAME
    Publication number: 20100152276
    Abstract: This invention is directed to deuterated aminocyclohexyl ether compounds and processes for preparing same and methods of using same.
    Type: Application
    Filed: February 26, 2010
    Publication date: June 17, 2010
    Applicant: Cardiome Pharma Corp.
    Inventors: Doug Ta Hung Chou, Bertrand M. C. Plouvier, Peter Pang, James Gee Ken Yee, Jeffery Jerome Wheeler, Aregahegn S. Yifru, Allen W. Davidoff
  • Deuterated aminocyclohexyl ether compounds and processes for preparing same
    Patent number: 7705036
    Abstract: This invention is directed to deuterated aminocyclohexyl ether compounds and processes for preparing same and methods of using same.
    Type: Grant
    Filed: October 13, 2006
    Date of Patent: April 27, 2010
    Assignee: Cardiome Pharma Corp.
    Inventors: Doug Ta Hung Chou, Bertrand M.C. Plouvier, Peter Pang, James Gee Ken Yee, Jeffrey Jerome Wheeler, Aregahegn S. Yifru, Allen W. Davidoff
  • ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF
    Publication number: 20100056603
    Abstract: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
    Type: Application
    Filed: March 26, 2009
    Publication date: March 4, 2010
    Applicant: CARDIOME PHARMA CORP.
    Inventors: Gregory N. Beatch, Bertrand M.C. Plouvier, Tao Sheng, Michael J.A. Walker, Richard A. Wall, Sandro L. Yong, Jeff Jiqun Zhu, Alexander R. Zolotoy
  • ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF
    Publication number: 20100029639
    Abstract: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
    Type: Application
    Filed: April 15, 2009
    Publication date: February 4, 2010
    Applicant: CARDIOME PHARMA CORP.
    Inventors: Allen I. Bain, Gregory N. Beatch, Cindy J. Longley, Bertrand M. C. Plouvier, Tao Sheng, Michael J. A. Walker, Richard A. Wall, Sandro L. Yong, Jeff Jiqun Zhu, Alexander B. Zolotoy
  • Ion channel modulating compounds and uses thereof
    Patent number: 7534790
    Abstract: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
    Type: Grant
    Filed: November 21, 2007
    Date of Patent: May 19, 2009
    Assignee: Cardiome Pharma Corp.
    Inventors: Allen I. Bain, Gregory N. Beatch, Cindy J. Longley, Bertrand M. C. Plouvier, Tao Sheng, Michael J. A. Walker, Richard A. Wall, Sandro L. Yong, Jeff Jiqun Zhu, Alexander B. Zolotoy
  • Ion channel modulating compounds and uses thereof
    Patent number: 7524879
    Abstract: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
    Type: Grant
    Filed: June 4, 2007
    Date of Patent: April 28, 2009
    Assignee: Cardiome Pharma Corp.
    Inventors: Gregory N. Beatch, Bertrand M. C. Plouvier, Tao Sheng, Michael J. A. Walker, Richard A. Wall, Sandro L. Yong, Jeff Jiqun Zhu, Alexander R. Zolotoy
  • PRODRUGS OF ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF
    Publication number: 20090105256
    Abstract: Prodrugs of ion channeling modulating compounds, including, for example, prodrugs of the ion channel modulating compound of the following formula: are described herein, as well as methods of making and using such prodrugs and pharmaceutical compositions containing such prodrugs.
    Type: Application
    Filed: March 31, 2005
    Publication date: April 23, 2009
    Applicant: Cardiome Pharma Corp.
    Inventors: Lewis Siu Leung Choi, Doug Ta Hung Chou, Allen W. Davidoff, Adewale Eniale, Bertrand M.C. Plouvier
  • Merged ion channel modulating compounds and Uses Thereof
    Publication number: 20090088464
    Abstract: Merged compounds of ion channel modulating compounds, including, for example, merged compounds of the ion channel modulating compound of the following formula: (I) are described herein, as well as methods of making and using such merged compounds and pharmaceutical compositions containing such merged compounds.
    Type: Application
    Filed: April 1, 2005
    Publication date: April 2, 2009
    Applicant: Cardiome Pharma Corp.
    Inventors: Lewis S.L. Choi, Doug Ta Hung Chou, Grace Jung, Bertrand M.C. Plouvier
  • Aminocyclohexyl ether compounds and uses thereof
    Patent number: 7345087
    Abstract: Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.
    Type: Grant
    Filed: March 30, 2006
    Date of Patent: March 18, 2008
    Assignee: Cardiome Pharma Corp.
    Inventors: Gregory N. Beatch, Bertrand M. C. Plouvier, Tao Sheng, Michael J. A. Walker, Richard A. Wall, Sandro L. Yong, Jeff Jiqun Zhu, Alexander B. Zolotoy
  • Ion channel modulating compounds and uses thereof
    Patent number: 7259184
    Abstract: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.
    Type: Grant
    Filed: January 27, 2006
    Date of Patent: August 21, 2007
    Assignee: Cardiome Pharma Corp.
    Inventors: Gregory N Beatch, Bertrand M C Plouvier, Tao Sheng, Michael J A Walker, Richard A Wall, Sandro L Yong, Jeff Jiqun Zhu, Alexander B Zolotoy