Patents by Inventor Beth A. Rasala

Beth A. Rasala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Colostrum/milk protein compositions
    Patent number: 10047371
    Abstract: Provided are colostrum and milk polypeptides recombinantly expressed in photosynthetic organisms containing colostrum and milk polypeptides, compositions comprising such organisms and methods for producing such organisms.
    Type: Grant
    Filed: February 19, 2015
    Date of Patent: August 14, 2018
    Assignee: The Regents of the University of California
    Inventors: Stephen P. Mayfield, Beth A. Rasala, Miller Tran
  • Chloroplast Expressing Colostrum or Milk Polypeptides
    Publication number: 20170342434
    Abstract: Provided are chloroplasts engineered to recombinantly express mammalian colostrum and milk polypeptides photosynthetic organisms containing such chloroplasts, and compositions comprising such organisms and methods for producing such organisms. In certain embodiments, provided is a chloroplast comprising one or more polynucleotides encoding one or more mammalian milk or colostrum polypeptides selected from osteopontin, lactadherin, cathelicidin-1, lysozyme, lactoperoxidase, lingual antimicrobial peptide (LAP), alpha-lactalbumin, and soluble CD14.
    Type: Application
    Filed: August 11, 2017
    Publication date: November 30, 2017
    Applicant: The Regents of the University of California
    Inventors: Stephen P. MAYFIELD, Austin HALLGREN, Beth A. RASALA, Miller TRAN, Michael MAYFIELD
  • Chloroplast expressing colostrum or milk polypeptides
    Patent number: 9732351
    Abstract: Provided are chloroplasts engineered to recombinantly express mammalian colostrum and milk polypeptides, photosynthetic organisms containing such chloroplasts, and compositions comprising such organisms and methods for producing such organisms. In certain embodiments, provided is a chloroplast comprising one or more polynucleotides encoding one or more mammalian milk or colostrum polypeptides selected from osteopontin, lactadherin, cathelicidin-1, lysozyme, lactoperoxidase, lingual antimicrobial peptide (LAP), alpha-lactalbumin, and soluble CD14.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: August 15, 2017
    Assignee: The Regents of the University of California
    Inventors: Stephen P. Mayfield, Austin Hallgren, Beth A. Rasala, Miller Tran, Michael Mayfield
  • Production of Therapeutic Proteins in Photosynthetic Organisms
    Publication number: 20170009250
    Abstract: The present disclosure relates to methods of expressing therapeutic proteins in photosynthetic organisms and the therapeutic proteins produced by the methods. The therapeutic proteins include high-mobility group box 1 (HMGB1) protein, fibronectin domain (10) (10FN3), fibronectin domain (14) (14FN3), interferon beta (IFN?), proinsulin and vascular endothelial growth factor (VEGF). The photosynthetic organisms include prokaryotes such as cyanobacteria and eukaryotes such as alga and plants. Transformation of eukaryotes is preferably the plastid genome, more preferably the chloroplast genome.
    Type: Application
    Filed: January 28, 2016
    Publication date: January 12, 2017
    Applicants: Sapphire Energy, Inc., The Scripps Research Institute
    Inventors: Beth A. Rasala, Rosa M. F. Cardoso, Machiko Muto, Stephen P. Mayfield, Philip A. Lee, Craig A. Behnke, Michael Mendez
  • COLOSTRUM/MILK PROTEIN COMPOSITIONS
    Publication number: 20160369291
    Abstract: Provided are colostrum and milk polypeptides recombinantly expressed in photosynthetic organisms containing colostrum and milk polypeptides, compositions comprising such organisms and methods for producing such organisms.
    Type: Application
    Filed: February 19, 2015
    Publication date: December 22, 2016
    Applicant: The Regents of the University of California
    Inventors: Stephen P. MAYFIELD, Beth A. RASALA, Miller TRAN
  • COLOSTRUM/MILK PROTEIN COMPOSITIONS
    Publication number: 20160257730
    Abstract: Provided are colostrum and milk polypeptides recombinantly expressed in photosynthetic organisms containing colostrum and milk polypeptides, compositions comprising such organisms and methods for producing such organisms.
    Type: Application
    Filed: April 22, 2016
    Publication date: September 8, 2016
    Applicant: The Regents of the University of California
    Inventors: Stephen P. MAYFIELD, Austin HALLGREN, Beth A. RASALA, Miller TRAN, Michael MAYFIELD
  • Production of Therapeutic Proteins in Photosynthetic Organisms
    Publication number: 20120309939
    Abstract: The present disclosure relates to methods of expressing therapeutic proteins in photosynthetic organisms and the therapeutic proteins produced by the methods. The therapeutic proteins include high-mobility group box 1 (HMGB1) protein, fibronectin domain (10) (10FN3), fibronectin domain (14) (14FN3), interferon beta (IFN?), proinsulin and vascular endothelial growth factor (VEGF). The photosynthetic organisms include prokaryotes such as cyanobacteria and eukaryotes such as alga and plants. Transformation of eukaryotes is preferably the plastid genome, more preferably the chloroplast genome.
    Type: Application
    Filed: November 19, 2010
    Publication date: December 6, 2012
    Applicants: THE SCRIPPS RESEARCH INSTITUTE, SAPPHIRE ENERGY, INC.
    Inventors: Beth A. Rasala, Rosa M. F. Cardoso, Machiko Muto, Stephen P. Mayfield, Philip A. Lee, Craig A. Behnke, Michael Mendez