Patents by Inventor Beth Arnold

Beth Arnold has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Large scale affinity chromatography of macromolecules
    Patent number: 6372425
    Abstract: A process of purifying target molecules is described that involves the selection of ligands based on identifying, in real time, association and dissociation constants with a given target molecule; using this information to select at least one ligand that exhibit predetermined association and dissociation constants with a given target molecule; anchoring a quantity of ligand to an activated solid support; contacting a quantity of target molecules with the anchored ligand(s); removing low affinity target molecules from anchored ligand and eluting particularly pure target molecules.
    Type: Grant
    Filed: August 21, 1998
    Date of Patent: April 16, 2002
    Assignee: Merck & Co., Inc.
    Inventors: Beth Arnold, Paul M. Keller, Anthony J. Conley, Alan R. Shaw, Jwu-Sheng Tung
  • HIV-specific synthetic antigens and their use
    Patent number: 5763574
    Abstract: Immunological conjugates of HIV-specific selected principal neutralization epitopes are prepared. These epitopes bind 19b, a broadly neutralizing human monoclonal antibody specific for the HIV gp120. The epitopes are identified from oligopeptide epitope libraries. The conjugates are useful for vaccination against AIDS or ARC, as well as in the production of other HIV-specific broadly neutralizing antibodies for passive immunity against AIDS or ARC.
    Type: Grant
    Filed: April 4, 1996
    Date of Patent: June 9, 1998
    Assignee: Merck & Co., Inc.
    Inventors: Anthony J. Conley, Beth A. Arnold, Lynn J. Boots, Paul M. Keller