Patents by Inventor Beth Frances Ladin

Beth Frances Ladin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant proteolytic enzymes and method of production
    Patent number: 6403331
    Abstract: Mutant Bacillus lentus DSM 5483 proteases are derived by the replacement of at least one amino acid residue of the mature form of the B. lentus DSM 5483 alkaline protease. The mutant proteases are expressed by genes which are mutated by site-specific mutagenesis. The amino acid sites selected for replacement are identified by means of a computer based method which compares the three dimensional structure of the wild-type protease and a reference protease.
    Type: Grant
    Filed: May 31, 2000
    Date of Patent: June 11, 2002
    Assignee: Henkel Konnarditgesellshaft auf Aktien
    Inventors: Teresa Christianson, Dean Goddette, Beth Frances Ladin, Maria R. Lau, Christian Paech, Robert B. Reynolds, Charles R. Wilson, Shiow-Shong Yang
  • Mutant proteolytic enzymes and method of production
    Patent number: 6136553
    Abstract: Mutant B. lentus DSM 5483 proteases are derived by the replacement of at least one amino acid residue of the mature form of the B. lentus DSM 5483 alkaline protease. The mutant proteases are expressed by genes which are mutated by site-specific mutagenesis. The amino acid sites selected for replacement are identified by means of a computer based method which compares the three dimensional structure of the wild-type protease and a reference protease.
    Type: Grant
    Filed: November 26, 1997
    Date of Patent: October 24, 2000
    Inventors: Teresa Christianson, Dean Goddette, Beth Frances Ladin, Maria R. Lau, Christian Paech, Robert B. Reynolds, Charles R. Wilson, Shiow-Shong Yang
  • Mutant proteolytic enzymes and method of production
    Patent number: 5985639
    Abstract: Mutant B. lentus DSM 5483 proteases are derived by the replacement of at least one amino acid residue of the mature form of the B. lentus DSM 5483 alkaline protease. The mutant proteases are expressed by genes which are mutated by site-specific mutagenesis. The amino acid sites selected for replacement are identified by means of a computer based method which compares the three dimensional structure of the wild-type protease and a reference protease.
    Type: Grant
    Filed: March 19, 1996
    Date of Patent: November 16, 1999
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Teresa Christianson, Dean Goddette, Beth Frances Ladin, Maria R. Lau, Christian Paech, Robert B. Reynolds, Charles R. Wilson, Shiow-Shong Yang