Patents by Inventor Beth Friedman

Beth Friedman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DEVICE FOR INDUCING VASCULAR INJURY AND/OR BLOCKAGE IN AN ANIMAL MODEL
    Publication number: 20070299331
    Abstract: Ultrashort laser pulses are used to induce photodisruptive breakdown in vasculature in an animal to controllably produce hemorrhage, thrombosis or breach of blood-brain barrier in individual, specifically targeted blood vessels. Damage is limited to the targeted vessels such that neighboring vessels exhibit no signs of vascular damage, including vessels directly above or below the targeted vessel. Ultrashort laser pulses of lower energy are also used to observe and quantify the baseline and altered states of blood flow. Observation and measurement may be performed (1) by TPLSM, OCT or other known techniques, providing a real-time, in vivo model for the dynamics and effects of vascular injury.
    Type: Application
    Filed: July 13, 2007
    Publication date: December 27, 2007
    Inventors: Beth FRIEDMAN, David KLEINFELD, Patrick LYDEN, Nozomi NISHIMURA, Christopher SCHAFFER, Lee SCHROEDER, Philbert TSAI
  • Device and method for inducing vascular injury and/or blockage in an animal model
    Patent number: 7258687
    Abstract: Ultrashort laser pulses are used to induce photodisruptive breakdown in vasculature in an animal to controllably produce hemorrhage, thrombosis or breach of the blood-brain barrier in individual, specifically-targeted blood vessels. Damage is limited to the targeted vessels such that neighboring vessels exhibit no signs of vascular damage, including vessels directly above and directly below the targeted vessel. Ultrashort laser pulses of lower energy are also used to observe and quantify the baseline and altered states of blood flow. Observation and measurement may be performed by TPLSM, OCT or other known techniques, providing a real-time, in vivo model for the dynamics and effects of vascular injury.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: August 21, 2007
    Assignee: The Regents of the University of California
    Inventors: Beth Friedman, David Kleinfeld, Patrick D. Lyden, Nozomi Nishimura, Christopher B. Schaffer, Lee Frederick Schroeder, Philbert Tsai
  • Device and method for inducing vascular injury and/or blockage in an animal model
    Publication number: 20060142746
    Abstract: Ultrashort laser pulses are used to induce photodisruptive breakdown in vasculature in an animal to controllably produce hemorrhage, thrombosis or breach of the blood-brain barrier in individual, specifically-targeted blood vessels. Damage is limited to the targeted vessels such that neighboring vessels exhibit no signs of vascular damage, including vessels directly above and directly below the targeted vessel. Ultrashort laser pulses of lower energy are also used to observe and quantify the baseline and altered states of blood flow. Observation and measurement may be performed by TPLSM, OCT or other known techniques, providing a real-time, in vivo model for the dynamics and effects of vascular injury.
    Type: Application
    Filed: December 11, 2003
    Publication date: June 29, 2006
    Inventors: Beth Friedman, David Kleinfeld, Patrick Lyden, Nozomi Nishimura, Christopher Schaffer, Lee Schroeder, Philbert Tsai