Patents by Inventor Beth Hill

Beth Hill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for delivering alpha-melanocyte stimulating hormone mimetibody composition comprising propylene glycol for intranasal administration to the central nervous system
    Patent number: 9732147
    Abstract: Pharmaceutical compositions and methods for delivering a polypeptide to the central nervous system of a mammal via intranasal administration are provided. The polypeptide can be a catalytically active protein or an antibody, antibody fragment or antibody fragment fusion protein. The polypeptides are formulated with one or more specific agents.
    Type: Grant
    Filed: September 24, 2014
    Date of Patent: August 15, 2017
    Assignee: Janssen Biotech, Inc.
    Inventors: Johanna Bentz, Beth Hill, Lisbeth Illum
  • Non-aqueous high concentration reduced viscosity suspension formulations of antibodies
    Patent number: 9072668
    Abstract: The present invention relates to non-aqueous high concentration reduced viscosity suspension formulations of antibodies and methods of making and using them.
    Type: Grant
    Filed: September 30, 2011
    Date of Patent: July 7, 2015
    Assignee: Janssen Biotech, Inc.
    Inventors: Weiguo Dai, Beth Hill, Kui Liu, Carl Mieczkowski
  • Propylene Glycol Compositions for Intranasal Administration of Active Agents to the Central Nervous System
    Publication number: 20150010557
    Abstract: Pharmaceutical compositions and methods for delivering a polypeptide to the central nervous system of a mammal via intranasal administration are provided. The polypeptide can be a catalytically active protein or an antibody, antibody fragment or antibody fragment fusion protein. The polypeptides are formulated with one or more specific agents.
    Type: Application
    Filed: September 24, 2014
    Publication date: January 8, 2015
    Inventors: Johanna Bentz, Beth Hill, Lisbeth Illum
  • Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations of Antibodies
    Publication number: 20120076800
    Abstract: The present invention relates to non-aqueous high concentration reduced viscosity suspension formulations of antibodies and methods of making and using them.
    Type: Application
    Filed: September 30, 2011
    Publication date: March 29, 2012
    Inventors: Weiguo Dai, Beth Hill, Kui Liu, Carl Mieczkowski
  • Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations
    Publication number: 20110223208
    Abstract: The present invention relates to non-aqueous high concentration reduced viscosity suspension formulations and methods of making and using them.
    Type: Application
    Filed: March 9, 2011
    Publication date: September 15, 2011
    Inventors: Beth Hill, Weiguo Dai
  • Intranasal Administration of Active Agents to the Central Nervous System
    Publication number: 20090136505
    Abstract: Pharmaceutical compositions and methods for delivering a polypeptide to the central nervous system of a mammal via intranasal administration are provided. The polypeptide can be a catalytically active protein or an antibody, antibody fragment or antibody fragment fusion protein. The polypeptides are formulated with one or more specific agents.
    Type: Application
    Filed: October 31, 2007
    Publication date: May 28, 2009
    Inventors: Johanna Bentz, Beth Hill, Lisbeth Illum
  • Macromolecular conjugates of bone morphogenetic protein-7
    Publication number: 20070015701
    Abstract: A modified bone morphogenetic protein (BMP, also referred to as bone morphogenic protein) composition is described. The bone morphogenetic protein, in one embodiment, is BMP-7 which is chemically modified with a hydrophilic polymer, such as poly(ethylene glycol).
    Type: Application
    Filed: May 31, 2006
    Publication date: January 18, 2007
    Inventors: Samuel Zalipsky, Francis Farrell, Beth Hill, Radwan Kiwan
  • Intranasal administration of active agents to the central nervous system
    Publication number: 20060188496
    Abstract: A method for delivering a polypeptide to the central nervous system of a mammal is provided. The method involves attaching the polypeptide to an antibody or an antibody fragment and administering the fusion polypeptide intranasally, for delivery to the central nervous system. Methods of treatment are also provided, where a therapeutically effective amount of the composition is delivered to the nasal cavity of a mammal.
    Type: Application
    Filed: January 27, 2006
    Publication date: August 24, 2006
    Inventors: Hanne Bentz, Beth Hill, Catherine Lucas, William Frey
  • Stable suspension formulations of erythropoietin receptor agonists
    Publication number: 20060030526
    Abstract: A suspension formulation for therapeutic use includes a non-aqueous, single-phase vehicle exhibiting viscous fluid characteristics and a particle formulation comprising an erythropoietin receptor agonist dispersed in the vehicle.
    Type: Application
    Filed: August 1, 2005
    Publication date: February 9, 2006
    Inventors: Kui Liu, Michael Desjardin, Beth Hill, Zengji Li