Patents by Inventor Beth J. Hoffman

Beth J. Hoffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CDNA clone of a rat serotonin transporter and protein encoded thereby
    Patent number: 5552308
    Abstract: The invention described in this disclosure relates to a cloned cDNA encoding the serotonin transporter protein (5HTT) usually found in cells of part of the central nervous system, gut, adrenal gland and in platelets. The invention is further directed to the purified serotonin transporter protein and its use and immunogen for the production of anti-5HTT antibodies. The disclosure also discussses methods for use of the cDNA for diagnostic and treatment applications, and methods for use of permanent cell lines transformed with the serotonin transporter cDNA for pharmaceutical screening. The use of anti-5HTT antibodies as a diagnostic tool is also addressed.
    Type: Grant
    Filed: October 24, 1991
    Date of Patent: September 3, 1996
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Beth J. Hoffman, Eva Mezey, Michael J. Brownstein