Patents by Inventor Beth Levine

Beth Levine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small molecule inducers of autophagy
    Publication number: 20230203020
    Abstract: Small molecule disruptors of Beclin-1/Bcl-2 protein-protein interactions induce autophagy and hence are useful for treating a variety of indications where stimulation of autophagy is therapeutically useful, including cancer, infection immunity, neurodegeneration, longevity.
    Type: Application
    Filed: February 11, 2023
    Publication date: June 29, 2023
    Applicant: Board of Regents, The University of Texas System
    Inventors: Jef De Brabander, Qiren Liang, Beth Levine, Wei-Chung Chiang
  • Small molecule inducers of autophagy
    Patent number: 11591319
    Abstract: Small molecule disruptors of Beclin-1/Bc1-2 protein-protein interactions induce autophagy and hence are useful for treating a variety of indications where stimulation of autophagy is therapeutically useful, including cancer, infection immunity, neurodegeneration, longevity.
    Type: Grant
    Filed: April 5, 2022
    Date of Patent: February 28, 2023
    Assignee: Board of Regents, The University of Texas System
    Inventors: Jef De Brabander, Qiren Liang, Beth Levine, Wei-Chung Chiang
  • Small molecule inducers of autophagy
    Publication number: 20220242854
    Abstract: Small molecule disruptors of Beclin-1/Bc1-2 protein-protein interactions induce autophagy and hence are useful for treating a variety of indications where stimulation of autophagy is therapeutically useful, including cancer, infection immunity, neurodegeneration, longevity.
    Type: Application
    Filed: April 5, 2022
    Publication date: August 4, 2022
    Applicant: Board of Regents, The University of Texas System
    Inventors: Jef De Brabander, Qiren Liang, Beth Levine, Wei-Chung Chiang
  • Small molecule inducers of autophagy
    Patent number: 11325898
    Abstract: Small molecule disruptors of Beclin-1/Bcl-2 protein-protein interactions induce autophagy and hence are useful for treating a variety of indications where stimulation of autophagy is therapeutically useful, including cancer, infection immunity, neurodegeneration, longevity.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: May 10, 2022
    Assignee: Board of Regents, The University of Texas System
    Inventors: Jef De Brabander, Qiren Liang, Beth Levine, Wei-Chung Chiang
  • Cyclic peptide epitopes and small-molecule mimics for inducing autophagy
    Patent number: 10993983
    Abstract: Disclosed herein are cyclic peptides that induce cellular autophagy and have significant cell penetration activity. Methods for inducing autophagy and thereby treating various diseases and conditions associated with impaired autophagy are provided.
    Type: Grant
    Filed: March 17, 2017
    Date of Patent: May 4, 2021
    Assignees: Trustees of Tufts College, Board of Regents of the University of Texas System
    Inventors: Joshua Kritzer, Beth Levine, Leila Peraro
  • Small molecule inducers of autophagy
    Publication number: 20210115024
    Abstract: Small molecule disruptors of Beclin-1/Bcl-2 protein-protein interactions induce autophagy and hence are useful for treating a variety of indications where stimulation of autophagy is therapeutically useful, including cancer, infection immunity, neurodegeneration, longevity.
    Type: Application
    Filed: December 4, 2020
    Publication date: April 22, 2021
    Applicant: Board of Regents, The University of Texas System
    Inventors: Jef De Brabander, Qiren Liang, Beth Levine, Wei-Chung Chiang
  • CYCLIC PEPTIDE EPITOPES AND SMALL-MOLECULE MIMICS FOR INDUCING AUTOPHAGY
    Publication number: 20190382443
    Abstract: Disclosed herein are cyclic peptides that induce cellular autophagy and have significant cell penetration activity. Methods for inducing autophagy and thereby treating various diseases and conditions associated with impaired autophagy are provided.
    Type: Application
    Filed: March 17, 2017
    Publication date: December 19, 2019
    Applicants: TRUSTEES OF TUFTS COLLEGE, BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: JOSHUA KRITZER, BETH LEVINE, LEILA PERARO
  • Expandable article of footwear
    Patent number: 4265032
    Abstract: An expandable article of footwear having a sole with an upper formed over at least a portion of the sole. At least a part of the upper has formed therein an array of elongated slits. The slits are colinearly arranged into substantially parallel columns with the slits spaced part in the columnar direction. The slits of adjacent columns are in staggered relationship with each other. In this manner, when the article of footwear is worn, the openings defined by the slits expand into a generally oval shape.
    Type: Grant
    Filed: June 14, 1979
    Date of Patent: May 5, 1981
    Assignee: Betherb, Inc.
    Inventor: Beth Levine
  • Footwear
    Patent number: 4064641
    Abstract: An article of footwear having a shoe portion including an upper with a mouth, and a tubular portion adapted to be selectively coupled to the shoe portion. A fastener interconnects one end of the tubular portion to the mouth of the upper. A reversible cuff on the tubular portion is available to conceal the connected fastener and a reversible collar on the shoe portion is available to conceal the unconnected fastener and to prevent any abrasive contact with the leg of the wearer. When the shoe portion is used alone there is provided an ankle boot, and when used in combination with the tubular portion there is provided a calf high boot.
    Type: Grant
    Filed: November 26, 1976
    Date of Patent: December 27, 1977
    Assignee: Betherb, Inc.
    Inventor: Beth Levine