Patents by Inventor BethAnn Friedman

BethAnn Friedman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enhanced in vivo uptake of glucocerebrosidase
    Patent number: 5549892
    Abstract: A pharmaceutical composition comprising remodelled recombinant glucocerebrosidase (GCR) is described that provides a therapeutic effect at doses that are lower then those required using remodelled naturally occurring GCR. A method of treating patients with Gaucher's disease using remodelled recombinant GCR is also provided. In vivo uptake of exogenous molecules can be determined by extracting a mixture of cells from a subject, enriching the target cells in vitro, lysing the cells and determining the amount of exogenous molecules.
    Type: Grant
    Filed: June 21, 1993
    Date of Patent: August 27, 1996
    Assignee: Genzyme Corporation
    Inventors: BethAnn Friedman, Michael Hayes