Patents by Inventor Bettina Riebel

Bettina Riebel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for NAD(P)(H) oxidases
    Patent number: 7163815
    Abstract: The present invention is directed to compositions and methods comprising NAD(P)H oxidases, particularly bacterial oxidases, nucleic acids, recombinant plasmid vectors and recombinant proteins therein encoded, and host cells comprising the oxidases and nucleic acids. The present invention also comprises an isolated bacterial oxidase that oxidizes both NADH and NADPH. Methods for producing the enzymes and enzymatic reactions comprising use of NAD(P)H oxidases and products of such reactions are also disclosed.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: January 16, 2007
    Assignee: Georgia Tech Research Corporation
    Inventors: Bettina Riebel-Bommarius, Andreas Bommarius, Phillip Gibbs, William Wellborn
  • (R)-specific alcohol dehydrogenases from lactobacillus with improved catalytic activity using an NAD+ substrate
    Patent number: 6413750
    Abstract: In a method for improving the NADH specificity of preferred NADPH-dependent dehydrogenases, the alkalinity of the enzyme is reduced in the coenzyme docking area by an appropriate change of the amino acid sequence achieved by genetic engineering means. The inventive process is especially used for obtaining short-chain dehydrogenases with coenzyme binding areas on the N-terminus from Lactobacillus brevis and Lactobacillus kefir.
    Type: Grant
    Filed: November 18, 1999
    Date of Patent: July 2, 2002
    Assignee: Forschungszentrum Jülich GmbH
    Inventors: Werner Hummel, Bettina Riebel
  • Alcohol dehydrogenase and its use for the enzymatic production of chiral hydroxy compounds
    Patent number: 6225099
    Abstract: Stable microbial enzyme with alcohol dehydrogenase activity having an activity maximum at ca. 50° C., process for its isolation and its use for the enantioselective reduction/oxidation of organic keto compounds/hydroxy compounds wherein, depending on the type of the starting compounds R- or S-hydroxy compounds are obtained. In particular an alcohol dehydrogenase obtainable from Lactobacillus brevis has proven to be suitable.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: May 1, 2001
    Assignee: Forschungszentrum Jülich GmbH
    Inventors: Werner Hummel, Bettina Riebel
  • Alcohol dehydrogenase and its use for the enzymatic production of chiral hydroxy compounds
    Patent number: 6037158
    Abstract: Stable microbial enzyme with alcohol dehydrogenase activity having an activity maximum at ca. 50.degree. C., process for its isolation and its use for the enantioselective reduction/oxidation of organic keto compounds/hydroxy compounds wherein, depending on the type of the starting compounds R- or S-hydroxy compounds are obtained. In particular an alcohol dehydrogenase obtainable from Lactobacillus brevis has proven to be suitable.
    Type: Grant
    Filed: March 21, 1997
    Date of Patent: March 14, 2000
    Assignee: Forschungszentrum Julich GmbH
    Inventors: Werner Hummel, Bettina Riebel