Patents by Inventor Bettina VON NEUBECK

Bettina VON NEUBECK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-CD73 monoclonal antibody, encoding nucleic acids and method for producing
    Patent number: 11530273
    Abstract: The present invention relates to improved anti-CD73 antibodies which, in comparison to prior art anti-CD73 antibodies bind to a membrane-bound form of CD73 protein having cancer-promoting role and inhibit its enzymatic activity, while essentially not inhibiting a soluble form of CD73 protein involved in cardioprotection. The present invention further relates to methods of generation of such specific anti-CD73 antibodies and uses thereof including uses as medicaments and in methods for treatment, amelioration, prophylaxis and diagnostics of cancer.
    Type: Grant
    Filed: May 23, 2018
    Date of Patent: December 20, 2022
    Assignee: Helmholtz Zentrum München—Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH)
    Inventors: Reinhard Zeidler, Bettina Von Neubeck, Regina Feederle, Stefanie Hauck
  • NOVEL CD73 ANTIBODY, PREPARATION AND USES THEREOF
    Publication number: 20200148781
    Abstract: The present invention relates to improved anti-CD73 antibodies which, in comparison to prior art anti-CD73 antibodies bind to a membrane-bound form of CD73 protein having cancer-promoting role and inhibit its enzymatic activity, while essentially not inhibiting a soluble form of CD73 protein involved in cardioprotection. The present invention further relates to methods of generation of such specific anti-CD73 antibodies and uses thereof including uses as medicaments and in methods for treatment, amelioration, prophylaxis and diagnostics of cancer.
    Type: Application
    Filed: May 23, 2018
    Publication date: May 14, 2020
    Inventors: Reinhard ZEIDLER, Bettina VON NEUBECK, Regina FEEDERLE, Stefanie HAUCK