Patents by Inventor Betty Schwartz

Betty Schwartz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Edible plant parts enriched with probiotic bacteria
    Patent number: 11957721
    Abstract: The present invention relates to edible plant parts or tissues comprising probiotic bacteria and use thereof for oral delivery of the probiotic bacteria to an organism and enriching and/or improving the organism gastrointestinal tract microbiome. The present invention further relates to methods for selecting and/or producing probiotic bacteria capable of colonizing a plant tissue.
    Type: Grant
    Filed: April 10, 2019
    Date of Patent: April 16, 2024
    Assignees: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD., OFEK—ESHKOLOT RESEARCH AND DEVELOPMENT LTD.
    Inventors: Oded Shoseyov, Sigal Baruch-Sharon, Betty Schwartz, Lilach Iasur Kruh, Roni Almon, Alaa Naama-Amar
  • EDIBLE PLANT PARTS ENRICHED WITH PROBIOTIC BACTERIA
    Publication number: 20210030819
    Abstract: The present invention relates to edible plant parts or tissues comprising probiotic bacteria and use thereof for oral delivery of the probiotic bacteria to an organism and enriching and/or improving the organism gastrointestinal tract microbiome. The present invention further relates to methods for selecting and/or producing probiotic bacteria capable of colonizing a plant tissue.
    Type: Application
    Filed: April 10, 2019
    Publication date: February 4, 2021
    Inventors: Oded SHOSEYOV, Sigal BARUCH-SHARON, Betty SCHWARTZ, Roni ALMON, Naama ALAA
  • METHOD OF TREATING A LIVER DISEASE COMPRISING ADMINISTERING OSTREOLYSIN ORFUNCTIONALLY RELATED VARIANT THEREOF
    Publication number: 20200397848
    Abstract: Disclosed are methods for treating, preventing and alleviating obesity, fatty liver syndrome, diabetes, one or more metabolic syndrome conditions or complications and/or cancer comprising administering an effective amount of ostreolysin, its functionally related variant, or an extract or mushroom extract comprising the same to subjects in need thereof.
    Type: Application
    Filed: June 3, 2020
    Publication date: December 24, 2020
    Inventors: Betty SCHWARTZ, Einav YEHUDA-SHNAIDMAN, Lili NIMRI
  • Method of treating a liver disease comprising administering ostreolysin orfunctionally related variant thereof
    Patent number: 10716825
    Abstract: Disclosed are methods for treating, preventing and alleviating obesity, fatty liver syndrome, diabetes, one or more metabolic syndrome conditions or complications and/or cancer comprising administering an effective amount of ostreolysin, its functionally related variant, or an extract or mushroom extract comprising the same to subjects in need thereof.
    Type: Grant
    Filed: November 1, 2019
    Date of Patent: July 21, 2020
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Betty Schwartz, Einav Yehuda-Shnaidman, Lili Nimri
  • METHOD OF TREATING OVERWEIGHT OR OBESITY COMPRISING ADMINISTERING A PLEUROTUS OSTREATUS MUSHROOM EXTRACT OR A COMPOSITION COMPRISING A PLEUROTUS OSTRETUS MUSHROOM EXTRACT
    Publication number: 20200085905
    Abstract: Disclosed are methods for treating, preventing and alleviating obesity, fatty liver syndrome, diabetes, one or more metabolic syndrome conditions or complications and/or cancer comprising administering an effective amount of ostreolysin, its functionally related variant, or an extract or mushroom extract comprising the same to subjects in need thereof.
    Type: Application
    Filed: November 1, 2019
    Publication date: March 19, 2020
    Inventors: Betty SCHWARTZ, Einav YEHUDA-SHNAIDMAN, Lili NIMRI
  • CRYOPRESERVATION METHOD OF BIOLOGICAL SPECIMEN
    Publication number: 20200077642
    Abstract: The invention relates to a method for cryopreserving a biological sample adhered to a substrate. The method of the invention comprises freezing of adherent cells and/or intact multicellular ensembles, without detaching them from the substrate or from each other. This method utilizes a directional freezing approach, which enables control over ice crystals shape, ice growth rate and position, which have a crucial impact on the physiological revival of the sample upon thawing. The invention further relates to samples cryopreserved according to the method of the invention.
    Type: Application
    Filed: December 5, 2017
    Publication date: March 12, 2020
    Inventors: Ido BRASLAVSKY, Victor YASHUNSKY, Amir BEIN, Liat BAHARI, Betty SCHWARTZ
  • METHOD OF TREATING OVERWEIGHT OR OBESITY COMPRISING ADMINISTERING A PLEUROTUS OSTREATUS MUSHROOM EXTRACT OR A COMPOSITION COMPRISING A PLEUROTUS OSTRETUS MUSHROOM EXTRACT
    Publication number: 20200061135
    Abstract: Disclosed are methods for treating, preventing and alleviating obesity, fatty liver syndrome, diabetes, one or more metabolic syndrome conditions or complications and/or cancer comprising administering an effective amount of ostreolysin, its functionally related variant, or an extract or mushroom extract comprising the same to subjects in need thereof.
    Type: Application
    Filed: October 16, 2019
    Publication date: February 27, 2020
    Inventors: Betty SCHWARTZ, Einav YEHUDA-SHNAIDMAN, Lili NIMRI
  • Method of treating overweight or obesity comprising administering a pleurotus ostreatus mushroom extract or a composition comprising a pleurotus ostretus mushroom extract
    Patent number: 10493123
    Abstract: Disclosed are methods for treating, preventing and alleviating obesity, fatty liver syndrome, diabetes, one or more metabolic syndrome conditions or complications and/or cancer comprising administering an effective amount of ostreolysin, its functionally related variant, or an extract or mushroom extract comprising the same to subjects in need thereof.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: December 3, 2019
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF of The Hebrew University of Jerusalem LTD.
    Inventors: Betty Schwartz, Einav Yehuda-Shnaidman, Lili Nimri
  • OSTREOLYSIN, FUNCTIONALLY RELATED VARIANT THEREOF, EXTRACT COMPRISING OSTREOLYSIN AND USES THEREOF
    Publication number: 20170368133
    Abstract: Disclosed are methods for treating, preventing and alleviating obesity, fatty liver syndrome, diabetes, one or more metabolic syndrome conditions or complications and/or cancer comprising administering an effective amount of ostreolysin, its functionally related variant, or an extract or mushroom extract comprising the same to subjects in need thereof.
    Type: Application
    Filed: March 18, 2015
    Publication date: December 28, 2017
    Inventors: Betty SCHWARTZ, Einav YEHUDA-SHNAIDMAN, Lili NIMRI
  • ACTIN BINDING PEPTIDES AND COMPOSITIONS COMPRISING SAME FOR INHIBITING ANGIOGENESIS AND TREATING MEDICAL CONDITIONS ASSOCIATED WITH SAME
    Publication number: 20160340659
    Abstract: The present invention, in some embodiments thereof, relates to biologically active peptides and, more particularly, but not exclusively, to peptides from T2 RNase (RNASET2) having actin binding, pharmaceutical compositions comprising the same, therapeutic use thereof and methods for their production.
    Type: Application
    Filed: January 29, 2015
    Publication date: November 24, 2016
    Inventors: Oded SHOSEYOV, Betty SCHWARTZ, Shani DORON, Liron NESIEL, Assaf FRIEDLER, Hadar AMARTELY, Levava ROIZ, Patricia SMIRNOFF, Iris LEWIN
  • Methods of and compositions for inhibiting the proliferation of mammalian cells
    Patent number: 8735127
    Abstract: A method of preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The method is effected by administering to the subject a therapeutically effective amount of a ribonuclease of the T2 family having actin binding activity.
    Type: Grant
    Filed: September 9, 2013
    Date of Patent: May 27, 2014
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Levava Roiz, Betty Schwartz, Patricia Smirnoff, Oded Shoseyov
  • METHODS OF AND COMPOSITIONS FOR INHIBITING THE PROLIFERATION OF MAMMALIAN CELLS
    Publication number: 20140011729
    Abstract: A method of preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The method is effected by administering to the subject a therapeutically effective amount of a ribonuclease of the T2 family having actin binding activity.
    Type: Application
    Filed: September 9, 2013
    Publication date: January 9, 2014
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Levava ROIZ, Betty Schwartz, Patricia Smirnoff, Oded Shoseyov
  • Methods of and compositions for inhibiting the proliferation of mammalian cells
    Patent number: 8617867
    Abstract: A method of preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The method is effected by administering to the subject a therapeutically effective amount of a ribonuclease of the T2 family having actin binding activity.
    Type: Grant
    Filed: January 1, 2012
    Date of Patent: December 31, 2013
    Assignee: Yissum Research Develpment Company of the Hebrew University of Jerusalem
    Inventors: Levava Roiz, Betty Schwartz, Patricia Smirnoff, Oded Shoseyov
  • Methods of and compositions for inhibiting the proliferation of mammalian cells
    Patent number: 8236543
    Abstract: A method of preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The method is effected by administering to the subject a therapeutically effective amount of a ribonuclease of the T2 family having actin binding activity.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: August 7, 2012
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Levava Roiz, Betty Schwartz, Patricia Smirnoff, Oded Shoseyov
  • METHODS OF AND COMPOSITIONS FOR INHIBITING THE PROLIFERATION OF MAMMALIAN CELLS
    Publication number: 20120100128
    Abstract: A method of preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The method is effected by administering to the subject a therapeutically effective amount of a ribonuclease of the T2 family having actin binding activity.
    Type: Application
    Filed: January 1, 2012
    Publication date: April 26, 2012
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Levava Roiz, Betty Schwartz, Patricia Smirnoff, Oded Shoseyov
  • Recombinant human T2 RNase and uses thereof
    Patent number: 8039240
    Abstract: The cloning and heterologous expression of human T2 RNase6PL are disclosed. Further disclosed are methods for preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The methods are effected by administering to the subject a therapeutically effective amount of a RNase6PL ribonuclease or close homologues thereof.
    Type: Grant
    Filed: September 28, 2005
    Date of Patent: October 18, 2011
    Assignee: Yissum Reseach Development Company of the Hebrew University of Jerusalem
    Inventors: Levava Roiz, Betty Schwartz, Patricia Smirnoff, Oded Shoseyov
  • EFFICIENT EXPRESSION OF TRUNCATED HUMAN RNASET2 IN E. COLI
    Publication number: 20110207667
    Abstract: An isolated, recombinant truncated human RNASET2 having anti-angiogenic properties, methods for efficient expression thereof in bacteria and therapeutic uses thereof.
    Type: Application
    Filed: October 29, 2009
    Publication date: August 25, 2011
    Inventors: Oded Shoseyou, Betty Schwartz, Levava Roiz, Patricia Smirnoff, Liron Nuttman
  • METHODS OF AND COMPOSITIONS FOR INHIBITING THE PROLIFERATION OF MAMMALIAN CELLS
    Publication number: 20110008314
    Abstract: A method of preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The method is effected by administering to the subject a therapeutically effective amount of a ribonuclease of the T2 family having actin binding activity.
    Type: Application
    Filed: September 27, 2010
    Publication date: January 13, 2011
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Levava Roiz, Betty Schwartz, Patricia Smirnoff, Oded Shoseyov
  • Methods of and compositions for inhibiting the proliferation of mammalian cells
    Patent number: 7811981
    Abstract: A method of preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The method is effected by administering to the subject a therapeutically effective amount of a ribonuclease of the T2 family having actin binding activity.
    Type: Grant
    Filed: September 29, 2004
    Date of Patent: October 12, 2010
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Levava Roiz, Betty Schwartz, Patricia Smirnoff, Oded Shoseyov
  • Recombinant Human T2 Rnase and Uses Thereof
    Publication number: 20080131419
    Abstract: The cloning and heterologous expression of human T2 RNase6PL are disclosed. Further disclosed are methods for preventing, inhibiting and/or reversing cell motility, actin filament assembly or disassembly, proliferation, colonization, differentiation, accumulation and/or development of abnormal cells in a subject is disclosed. The methods are effected by administering to the subject a therapeutically effective amount of a RNase6PL ribonuclease or close homologues thereof.
    Type: Application
    Filed: September 28, 2005
    Publication date: June 5, 2008
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem
    Inventors: Levava Roiz, Betty Schwartz, Patricia Smirnoff, Oded Shoseyov