Patents by Inventor Beverly Packard

Beverly Packard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5055561
    Abstract: A bridging molecule carrying a drug, or a label such as a fluorophore, which adds across disulfide bonds of molecules, particularly proteins, and methods of manufacturing and using the bridging molecules, are disclosed. The bridging molecule is reactive with sulfhydryl groups formed by the reduction of disulfide bonds of the protein. The functional groups of the bridging molecules are typically --SH groups.
    Type: Grant
    Filed: November 1, 1989
    Date of Patent: October 8, 1991
    Assignee: The Johns Hopkins University
    Inventors: Beverly Packard, Michael Edidin, Akira Komoriya
  • Patent number: 4889916
    Abstract: A bridging molecule carrying a drug, or a label such as a fluorophore, which adds across disulfide bonds of molecules, particularly proteins, and methods of manfacturing and using the bridging molecules, are disclosed. The bridging molecule is reactive with sulfhydryl groups formed by the reduction of disulfide bonds of the protein. The functional groups of the bridging molecules are typically --SH groups.
    Type: Grant
    Filed: February 1, 1988
    Date of Patent: December 26, 1989
    Assignee: The Johns Hopkins University
    Inventors: Beverly Packard, Michael Edidin, Akira Komoriya
  • Patent number: 4751286
    Abstract: A bridging molecule carrying a drug, or a label such as a fluorophore, which adds across disulfide bonds of molecules, particularly proteins, and methods of manufacturing and using the bridging molecules, are disclosed. The bridging molecule is reactive with sulfhydryl groups formed by the reduction of disulfide bonds of the protein. The functional groups of the bridging molecules are typically --SH groups.
    Type: Grant
    Filed: November 19, 1985
    Date of Patent: June 14, 1988
    Assignee: The Johns Hopkins University
    Inventors: Beverly Packard, Michael Edidin, Akira Komoriya