Patents by Inventor Bhairab Singh

Bhairab Singh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods to enhance myocardial regeneration and/or repair
    Patent number: 11725217
    Abstract: A method is provided to enhance repair or regeneration of a mammalian cardiovascular system to include heart and/or vasculature comprising: administering to a mammal in need thereof a composition comprising an effective amount of an agent that elevates levels of Smo, Ptc1, Shh, Ihh, Dhh, Gli1, Gli2, or Mycn.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: August 15, 2023
    Assignee: Regents of the University of Minnesota
    Inventors: Daniel J. Garry, Mary G. Garry, Bhairab Singh
  • Regulation of mesodermal specification
    Patent number: 10858627
    Abstract: Disclosed is a method to differentiate stern, progenitor or precursor cells comprising contacting said stem, progenitor or precursor cells with miR-130a, or an RNA having at least 95% identity thereto, so as to yield cells of endothelial lineage. Further disclosed are compositions comprising the endothelial lineage cells obtained and methods of using the compositions for treating diseases including cardiovascular diseases.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: December 8, 2020
    Assignee: Regents of the University of Minnesota
    Inventors: Daniel J. Garry, Naoko Koyano-Nakagawa, Mary G. Garry, Bhairab Singh
  • METHODS TO ENHANCE MYOCARDIAL REGENERATION AND/OR REPAIR
    Publication number: 20200224218
    Abstract: A method is provided to enhance repair or regeneration of a mammalian cardiovascular system to include heart and/or vasculature comprising: administering to a mammal in need thereof a composition comprising an effective amount of an agent that elevates levels of Smo, Ptc1, Shh, Ihh, Dhh, Gli1, Gli2, or Mycn,
    Type: Application
    Filed: July 23, 2019
    Publication date: July 16, 2020
    Inventors: Daniel J. Garry, Mary G. Garry, Bhairab Singh
  • REGULATION OF MESODERMAL SPECIFICATION
    Publication number: 20190010458
    Abstract: Disclosed is a method to differentiate stern, progenitor or precursor cells comprising contacting said stem, progenitor or precursor cells with miR-130a, or an RNA having at least 95% identity thereto, so as to yield cells of endothelial lineage. Further disclosed are compositions comprising the endothelial lineage cells obtained and methods of using the compositions for treating diseases including cardiovascular diseases.
    Type: Application
    Filed: July 29, 2016
    Publication date: January 10, 2019
    Inventors: Daniel J. Garry, Naoko Koyano-Nakagawa, Mary G. Garry, Bhairab Singh