Patents by Inventor Bharath Takulapalli

Bharath Takulapalli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanopore sensor, structure and device including the sensor, and methods of forming and using same
    Patent number: 11977069
    Abstract: The present disclosure provides an improved device that can be used to sense and characterize a variety of materials. The device may be used for a variety of applications, including genome sequencing, protein sequencing, biomolecular sequencing, and detection of ions, molecules, chemicals, biomolecules, metal atoms, polymers, nanoparticles and the like.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: May 7, 2024
    Inventor: Bharath Takulapalli
  • FIELD EFFECT TRANSISTOR SENSOR DETECTION ASSAYS AND SYSTEMS AND METHODS OF MAKING AND USING SAME
    Publication number: 20240125777
    Abstract: Devices, systems and methods for detecting target analyte molecules or particles in a sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample are disclosed.
    Type: Application
    Filed: September 22, 2023
    Publication date: April 18, 2024
    Inventor: Bharath Takulapalli
  • Biosensor microarray compositions and methods
    Patent number: 11828753
    Abstract: Described herein are biosensor microarrays comprising detector polypeptide monolayers substantially free of contaminants. Also provided are methods for generation of such biosensor microarrays by capture of polypeptides by arrays comprising capture moieties and associated sensors.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: November 28, 2023
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Joshua Labaer, Bharath Takulapalli
  • FIELD EFFECT TRANSISTOR, DEVICE INCLUDING THE TRANSISTOR, AND METHODS OF FORMING AND USING SAME
    Publication number: 20220236264
    Abstract: The present disclosure provides an improved field effect transistor and device that can be used to sense and characterize a variety of materials. The field effect transistor and/or device including the transistor may be used for a variety of applications, including genome sequencing, protein sequencing, biomolecular sequencing, and detection of ions, molecules, chemicals, biomolecules, metal atoms, polymers, nanoparticles and the like.
    Type: Application
    Filed: April 15, 2022
    Publication date: July 28, 2022
    Inventor: Bharath Takulapalli
  • PROGRAMMABLE ARRAYS
    Publication number: 20220128547
    Abstract: Biomolecule arrays on a substrate are described which contain a plurality of biomolecules, such as coding nucleic acids and/or isolated polypeptides, at a plurality of discrete, isolated, locations. The arrays can be used, for example, in high throughput genomics and proteomics for specific uses including, but not limited molecular diagnostics for early detection, diagnosis, treatment, prognosis, monitoring clinical response, and protein crystallography.
    Type: Application
    Filed: June 2, 2021
    Publication date: April 28, 2022
    Inventors: Peter Wiktor, Joshua Labaer, Peter Kahn, Bharath Takulapalli, Ji Qiu, Al Brunner, Mitch Magee
  • Field effect transistor, device including the transistor, and methods of forming and using same
    Patent number: 11307200
    Abstract: The present disclosure provides an improved field effect transistor and device that can be used to sense and characterize a variety of materials. The field effect transistor and/or device including the transistor may be used for a variety of applications, including genome sequencing, protein sequencing, biomolecular sequencing, and detection of ions, molecules, chemicals, biomolecules, metal atoms, polymers, nanoparticles and the like.
    Type: Grant
    Filed: November 27, 2019
    Date of Patent: April 19, 2022
    Inventor: Bharath Takulapalli
  • BIOSENSOR MICROARRAY COMPOSITIONS AND METHODS
    Publication number: 20220042981
    Abstract: Described herein are biosensor microarrays comprising detector polypeptide monolayers substantially free of contaminants. Also provided are methods for generation of such biosensor microarrays by capture of polypeptides by arrays comprising capture moieties and associated sensors.
    Type: Application
    Filed: March 15, 2021
    Publication date: February 10, 2022
    Inventors: Joshua Labaer, Bharath Takulapalli
  • Biosensor microarray compositions and methods
    Patent number: 10983118
    Abstract: Described herein are biosensor microarrays comprising detector polypeptide monolayers substantially free of contaminants. Also provided are methods for generation of such biosensor microarrays by capture of polypeptides by arrays comprising capture moieties and associated sensors.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: April 20, 2021
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY
    Inventors: Joshua Labaer, Bharath Takulapalli
  • FIELD EFFECT TRANSISTOR SENSOR DETECTION ASSAYS AND SYSTEMS AND METHODS OF MAKING AND USING SAME
    Publication number: 20200386751
    Abstract: Devices, systems and methods for detecting target analyte molecules or particles in a sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample are disclosed.
    Type: Application
    Filed: November 29, 2018
    Publication date: December 10, 2020
    Applicant: iNanoBio, Inc.
    Inventor: Bharath Takulapalli
  • DISEASE PROTEOME PROTEIN ARRAYS AND USES THEREOF
    Publication number: 20200309773
    Abstract: Provided herein are methods of making and using disease-specific protein arrays. In particular, provided herein are embodiments of disease-specific protein arrays and their use in varied applications such as biomarker detection, diagnostics, elucidating signaling pathways, studying interaction networks and posttranslational modifications, and for drug discovery applications.
    Type: Application
    Filed: October 16, 2018
    Publication date: October 1, 2020
    Inventor: Bharath TAKULAPALLI
  • FIELD EFFECT TRANSISTOR, DEVICE INCLUDING THE TRANSISTOR, AND METHODS OF FORMING AND USING SAME
    Publication number: 20200096505
    Abstract: The present disclosure provides an improved field effect transistor and device that can be used to sense and characterize a variety of materials. The field effect transistor and/or device including the transistor may be used for a variety of applications, including genome sequencing, protein sequencing, biomolecular sequencing, and detection of ions, molecules, chemicals, biomolecules, metal atoms, polymers, nanoparticles and the like.
    Type: Application
    Filed: November 27, 2019
    Publication date: March 26, 2020
    Inventor: Bharath Takulapalli
  • Field effect transistor, device including the transistor, and methods of forming and using same
    Patent number: 10514380
    Abstract: The present disclosure provides an improved field effect transistor and device that can be used to sense and characterize a variety of materials. The field effect transistor and/or device including the transistor may be used for a variety of applications, including genome sequencing, protein sequencing, biomolecular sequencing, and detection of ions, molecules, chemicals, biomolecules, metal atoms, polymers, nanoparticles and the like.
    Type: Grant
    Filed: May 16, 2016
    Date of Patent: December 24, 2019
    Inventor: Bharath Takulapalli
  • NANOPORE SENSOR, STRUCTURE AND DEVICE INCLUDING THE SENSOR, AND METHODS OF FORMING AND USING SAME
    Publication number: 20190145950
    Abstract: The present disclosure provides an improved device that can be used to sense and characterize a variety of materials. The device may be used for a variety of applications, including genome sequencing, protein sequencing, biomolecular sequencing, and detection of ions, molecules, chemicals, biomolecules, metal atoms, polymers, nanoparticles and the like.
    Type: Application
    Filed: April 19, 2017
    Publication date: May 16, 2019
    Inventor: Bharath Takulapalli
  • SYSTEM AND METHOD FOR NUCLEOTIDE SEQUENCING
    Publication number: 20180299424
    Abstract: The present invention provides a system and method of sequencing complex molecules including DNA, RNA, proteins, and glycans. The method includes the steps of modifying a field effect nanopore transistor device with chemical recognition molecules, translocating the complex molecule into the field effect nanopore transistor device, applying bias potential to the silicon gate of the field effect nanopore transistor device, and measuring the resulting change in drain current across the source drain contacts.
    Type: Application
    Filed: November 10, 2015
    Publication date: October 18, 2018
    Inventors: Bharath Takulapalli, Stuart Lindsay
  • PROGRAMMABLE ARRAYS
    Publication number: 20180267029
    Abstract: Biomolecule arrays on a substrate are described which contain a plurality of biomolecules, such as coding nucleic acids and/or isolated polypeptides, at a plurality of discrete, isolated, locations. The arrays can be used, for example, in high throughput genomics and proteomics for specific uses including, but not limited molecular diagnostics for early detection, diagnosis, treatment, prognosis, monitoring clinical response, and protein crystallography.
    Type: Application
    Filed: March 28, 2018
    Publication date: September 20, 2018
    Inventors: Peter Wiktor, Joshua Labaer, Peter Kahn, Bharath Takulapalli, Ji Qiu, Al Brunner, Mitch Magee
  • FIELD EFFECT TRANSISTOR, DEVICE INCLUDING THE TRANSISTOR, AND METHODS OF FORMING AND USING SAME
    Publication number: 20160258941
    Abstract: The present disclosure provides an improved field effect transistor and device that can be used to sense and characterize a variety of materials. The field effect transistor and/or device including the transistor may be used for a variety of applications, including genome sequencing, protein sequencing, biomolecular sequencing, and detection of ions, molecules, chemicals, biomolecules, metal atoms, polymers, nanoparticles and the like.
    Type: Application
    Filed: May 16, 2016
    Publication date: September 8, 2016
    Inventor: Bharath Takulapalli
  • Field effect transistor, device including the transistor, and methods of forming and using same
    Patent number: 9341592
    Abstract: The present disclosure provides an improved field effect transistor and device that can be used to sense and characterize a variety of materials. The field effect transistor and/or device including the transistor may be used for a variety of applications, including genome sequencing, protein sequencing, biomolecular sequencing, and detection of ions, molecules, chemicals, biomolecules, metal atoms, polymers, nanoparticles and the like.
    Type: Grant
    Filed: April 9, 2013
    Date of Patent: May 17, 2016
    Assignees: iNanoBio LLC
    Inventors: Bharath Takulapalli, Abhinav Jain
  • BIOMARKER SENSOR ARRAY AND CIRCUIT AND METHODS OF USING AND FORMING SAME
    Publication number: 20160041155
    Abstract: The present disclosure relates to biomarker sensor arrays, to circuits including the sensor arrays, to systems including the arrays, and to methods of forming and using the arrays, circuits, and systems. The arrays, circuits, and systems can be used to detect a variety of materials, including chemical, biological, and radioactive materials. The arrays and circuits can be used for, for example, screening tests, disease diagnostics, prognostics and disease monitoring.
    Type: Application
    Filed: March 17, 2014
    Publication date: February 11, 2016
    Inventor: Bharath TAKULAPALLI
  • BIOSENSOR MICROARRAY COMPOSITIONS AND METHODS
    Publication number: 20160041159
    Abstract: Described herein are biosensor microarrays comprising detector polypeptide monolayers substantially free of contaminants. Also provided are methods for generation of such biosensor microarrays by capture of polypeptides by arrays comprising capture moieties and associated sensors.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 11, 2016
    Inventors: Joshua Labaer, Bharath Takulapalli
  • FIELD EFFECT TRANSISTOR, DEVICE INCLUDING THE TRANSISTOR, AND METHODS OF FORMING AND USING SAME
    Publication number: 20150060952
    Abstract: The present disclosure provides an improved field effect transistor and device that can be used to sense and characterize a variety of materials. The field effect transistor and/or device including the transistor may be used for a variety of applications, including genome sequencing, protein sequencing, biomolecular sequencing, and detection of ions, molecules, chemicals, biomolecules, metal atoms, polymers, nanoparticles and the like.
    Type: Application
    Filed: April 9, 2013
    Publication date: March 5, 2015
    Inventors: Bharath Takulapalli, Abhinav Jain