Patents by Inventor Bhaskar Krishna Arumugam
Bhaskar Krishna Arumugam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6872314Abstract: Disclosed is a process for dewatering an organic compound other than a carboxylic acid using a simulated moving bed (SMB) containing a solid with different absorptivities for water and the organic compound. The organic compound is fed into the SMB as an aqueous solution and desorbed with a desorbent other than water. The process is particularly useful for dewatering organic compounds produced by fermentation, biomass extraction, biocatalytic, and enzymatic processes.Type: GrantFiled: August 29, 2003Date of Patent: March 29, 2005Assignee: Eastman Chemical CompanyInventors: Brendan William Boyd, Bhaskar Krishna Arumugam
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Patent number: 6864376Abstract: The present invention comprises the use of sulfite additives to reduce discoloration of L-ascorbic acid produced from acid or aqueous solutions of 2-keto-L-gulonic acid. In one aspect, the present invention comprises a continuous process for producing L-ascorbic acid from an aqueous solution of 2-keto-L-gulonic acid. The use of sulfite additives reduces product stream color and improves product recovery by binding to high molecular weight reaction by-products. In a continuous process, the reaction stream is separated from residual sulfite and sulfite-bound by-products to produce a product stream enriched in aqueous ascorbic acid for recovery, and an enriched 2-keto-L-gulonic acid stream which is recycled to the reactor. The in situ use of sulfite additives during the reaction increases the overall yield of L-ascorbic acid, with no loss in selectivity of the synthesis.Type: GrantFiled: December 21, 2001Date of Patent: March 8, 2005Assignee: Eastman Chemical CompanyInventors: Steven Thomas Perri, Michael Roy Cushman, Jeffery Earl Grant Powell, Brendan William Boyd, Bhaskar Krishna Arumugam, Nick Allen Collins
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Patent number: 6670505Abstract: A process for recovering a desired organic acid from a solution includes the steps of: providing an aqueous solution including at least one desired organic acid or its acid anion; adjusting the proton concentration in the aqueous solution to a desired level, with the desired proton concentration being selected, at least in part, by the amount of available protons needed to associate with the acid anions of the desired organic acid(s) to be recovered and/or acid anions that are weaker than the desired organic acids; and recovering at least a portion of the at least one desired organic acid from the aqueous phase. The desired proton concentration can be based on the amount of available protons being greater than, less than or substantially equal, to the amount of protons needed to associate with the anion of the desired organic acid(s) and acid anions that are weaker than the desired organic acid(s).Type: GrantFiled: March 7, 2000Date of Patent: December 30, 2003Assignee: Eastman Chemical CompanyInventors: Nick Allen Collins, Mark Robert Shelton, George William Tindall, Steven Thomas Perri, Ruairi Seosamh O'Meadhra, Chester Wayne Sink, Bhaskar Krishna Arumugam, John Clark Hubbs
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Patent number: 6610863Abstract: The present invention provides methods and an apparatus for the manufacture of an L-ascorbic acid product in high yield by direct conversion of an aqueous solution containing 2-keto-L-gulonic acid by contact with an acid catalyst or under thermal self-catalyzed conditions at a conversion level that maximizes the formation of L-ascorbic acid and minimizes decomposition of the L-ascorbic acid thus formed. The separation process for L-ascorbic acid and KLG is operated in such a way that an efficient separation process allows the majority of the KLG to be recycled for further conversion. The product stream from the separation process is then subjected to a recovery step to obtain crystalline L-ascorbic acid product.Type: GrantFiled: December 21, 2001Date of Patent: August 26, 2003Assignee: Eastman Chemical CompanyInventors: Bhaskar Krishna Arumugam, Nick Allen Collins, Transito Lynne Macias, Steven Thomas Perri, Jeffrey Earl Grant Powell, Chester Wayne Sink, Michael Roy Cushman
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Patent number: 6527690Abstract: The invention relates to a process for purifying and decolorizing a phenyl ester salt. The process combines a phenyl ester salt with a solvent to form a mixture and then stirs the mixture to form a slurry. The phenyl ester salt is substantially insoluble in this solvent. The process then collects the phenyl ester salt from the slurry. The collected phenyl ester salt may then be optionally dried or recrystallized. The collected phenyl ester salt is dissolved in a solvent to form a solution. The solution is decolorized and then spray dried to form a powder of the phenyl ester salt. As a result of the process the phenyl ester salt powder has a higher purity and an improved color as compared to the starting phenyl ester salt.Type: GrantFiled: June 4, 2001Date of Patent: March 4, 2003Inventors: Bhaskar Krishna Arumugam, Michael Eugene Burns, Dimmick Lee Bymaster, Jeffrey Scott DuPont, Robert Richard Dykstra, Robert Lee Eagan, Eddie Joseph Eckart, Jarvey Eugene Felty, Jr., Kevin John Fontenot, Jeffrey William Green, Shane Kipley Kirk, Gary Paul Lutz, Tony Lee Sander, Thomas Hugh Williams, George Chester Zima
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Patent number: 6518454Abstract: Disclosed is a process wherein a solution of a carboxylic acid in a first solvent and an alcohol are fed to a simulated moving bed reactor (SMBR) containing a solid(s) to produce a first stream comprising a solution of an ester of the carboxylic acid and the alcohol and a second stream comprising the first solvent. The solid(s) present in the SMBR facilitates the esterification reaction and the separation of the first solvent from the carboxylic acid. The process is particularly valuable for the preparation of an alkanol solution of an alkyl 2-keto-L-gulonate ester (AKLG) from an aqueous fermentation broth containing dissolved 2-keto-L-gulonic acid (KLG) by feeding the fermentation broth and an alkanol to a simulated moving bed reactor which contains a solid acidic esterification catalyst to produce a stream comprising an alkanol solution of an ALKG. The alkanol solution of an ALKG may be used directly to convert the ALKG to ascorbic acid (Vitamin C).Type: GrantFiled: October 12, 2001Date of Patent: February 11, 2003Assignee: Eastman Chemical CompanyInventors: Bhaskar Krishna Arumugam, Larry Wayne Blair, Brendan William Boyd, Nick Allen Collins, David Anthony Larkin, Steven Thomas Perri, Chester Wayne Sink
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Patent number: 6476239Abstract: The present invention is a process for the preparation of ascorbic acid using a simulated moving bed (SMB) reactor system to accomplish the simultaneous conversion of KLG or a derivative of KLG to ascorbic acid and the separation of reaction products. The SMB reactor contains a solid or mixture of solids effective for catalyzing the reaction of KLG or its derivative and for separating the reactions products by selective adsorption of at least one product. In a general embodiment, this process involves (1) feeding a solution of KLG or a derivative thereof in a first solvent and a desorbent which is miscible with the first solvent, to a simulated moving bed reactor; (2) reacting the KLG or the KLG derivative to form ascorbic acid; and (3) removing from the simulated moving bed reactor (i) a first liquid stream comprising a solution of ascorbic acid in the desorbent and the first solvent (ii) a second liquid stream comprising the first solvent and the desorbent.Type: GrantFiled: February 12, 2002Date of Patent: November 5, 2002Assignee: Eastman Chemical CompanyInventors: Bhaskar Krishna Arumugam, Steven Thomas Perri, Elaine Beatrice Mackenzie, Larry Wayne Blair, Joseph Robert Zoeller
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Publication number: 20020151726Abstract: The present invention provides methods and an apparatus for the manufacture of an L-ascorbic acid product in high yield by direct conversion of an aqueous solution containing 2-keto-L-gulonic acid by contact with an acid catalyst or under thermal self-catalyzed conditions at a conversion level that maximizes the formation of L-ascorbic acid and minimizes decomposition of the L-ascorbic acid thus formed. The separation process for L-ascorbic acid and KLG is operated in such a way that an efficient separation process allows the majority of the KLG to be recycled for further conversion. The product stream from the separation process is then subjected to a recovery step to obtain crystalline L-ascorbic acid product.Type: ApplicationFiled: December 21, 2001Publication date: October 17, 2002Inventors: Bhaskar Krishna Arumugam, Nick Allen Collins, Transito Lynne Macias, Steven Thomas Perri, Jeffery Earl Grant Powell, Chester Wayne Sink, Michael Roy Cushman
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Publication number: 20020147352Abstract: The present invention comprises the use of sulfite additives to reduce discoloration of L-ascorbic acid produced from acid or aqueous solutions of 2-keto-L-gulonic acid. In one aspect, the present invention comprises a continuous process for producing L-ascorbic acid from an aqueous solution of 2-keto-L-gulonic acid. The use of sulfite additives reduces product stream color and improves product recovery by binding to high molecular weight reaction by-products. In a continuous process, the reaction stream is separated from residual sulfite and sulfite-bound by-products products to produce a product stream enriched in aqueous ascorbic acid for recovery, and an enriched 2-keto-L-gulonic acid stream which is recycled to the reactor. The in situ use of sulfite additives during the reaction increases the overall yield of L-ascorbic ascorbic acid, with no loss in selectivity of the synthesis.Type: ApplicationFiled: December 21, 2001Publication date: October 10, 2002Inventors: Steven Thomas Perri, Michael Roy Cushman, Jeffery Earl Grant Powell, Brendan William Boyd, Bhaskar Krishna Arumugam, Nick Allen Collins
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Publication number: 20020128505Abstract: The invention relates to a process for purifying and decolorizing a phenyl ester salt. The process combines a phenyl ester salt with a solvent to form a mixture and then stirs the mixture to form a slurry. The phenyl ester salt is substantially insoluble in this solvent. The process then collects the phenyl ester salt from the slurry. The collected phenyl ester salt may then be optionally dried or recrystallized. The collected phenyl ester salt is dissolved in a solvent to form a solution. The solution is decolorized and then spray dried to form a powder of the phenyl ester salt. As a result of the process the phenyl ester salt powder has a higher purity and an improved color as compared to the starting phenyl ester salt.Type: ApplicationFiled: June 4, 2001Publication date: September 12, 2002Inventors: Bhaskar Krishna Arumugam, Michael Eugene Burns, Dimmick Lee Bymaster, Jeffrey Scott Dupont, Robert Richard Dykstra, Robert Lee Eagan, Eddie Joseph Eckart, Jarvey Eugene Felty, Kevin John Fontenot, Jeffrey William Green, Shane Kipley Kirk, Gary Paul Lutz, Tony Lee Sander, Thomas Hugh Williams, George Chester Zima
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Publication number: 20020026077Abstract: A process for recovering a desired organic acid from a solution includes the steps of: providing an aqueous solution including at least one desired organic acid or its acid anion; adjusting the proton concentration in the aqueous solution to a desired level, with the desired proton concentration being selected, at least in part, by the amount of available protons needed to associate with the acid anions of the desired organic acid(s) to be recovered and/or acid anions that are weaker than the desired organic acids; and recovering at least a portion of the at least one desired organic acid from the aqueous phase. The desired proton concentration can be based on the amount of available protons being greater than, less than or substantially equal, to the amount of protons needed to associate with the anion of the desired organic acid(s) and acid anions that are weaker than the desired organic acid(s).Type: ApplicationFiled: August 3, 2001Publication date: February 28, 2002Inventors: Nick Allen Collins, Mark Robert Shelton, George William Tindall, Steven Thomas Perri, Ruairi Seosamh O'Meadhra, Chester Wayne Sink, Bhaskar Krishna Arumugam, John Clark Hubbs