Patents by Inventor Bhaskar Reddy Kusuma

Bhaskar Reddy Kusuma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • C-terminal HSP90 inhibitors
    Patent number: 12024536
    Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
    Type: Grant
    Filed: July 12, 2022
    Date of Patent: July 2, 2024
    Assignee: UNIVERSITY OF KANSAS
    Inventors: Brian S. J. Blagg, Bhaskar Reddy Kusuma, Teather Sundstrom
  • C-TERMINAL HSP90 INHIBITORS
    Publication number: 20230102047
    Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
    Type: Application
    Filed: July 12, 2022
    Publication date: March 30, 2023
    Inventors: Brian S.J. BLAGG, Bhaskar Reddy KUSUMA, Teather SUNDSTROM
  • C-terminal Hsp90 inhibitors
    Patent number: 11390640
    Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: July 19, 2022
    Assignee: UNIVERSITY OF KANSAS
    Inventors: Brian S. J. Blagg, Bhaskar Reddy Kusuma, Teather Sundstrom
  • C-TERMINAL HSP90 INHIBITORS
    Publication number: 20210188891
    Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
    Type: Application
    Filed: December 4, 2020
    Publication date: June 24, 2021
    Inventors: Brian S.J. BLAGG, Bhaskar Reddy KUSUMA, Teather SUNDSTROM
  • C-terminal Hsp90 inhibitors
    Patent number: 10882881
    Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
    Type: Grant
    Filed: February 5, 2020
    Date of Patent: January 5, 2021
    Assignee: UNIVERSITY OF KANSAS
    Inventors: Brian S. J. Blagg, Bhaskar Reddy Kusuma, Teather Sundstrom
  • C-TERMINAL HSP90 INHIBITORS
    Publication number: 20200283465
    Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
    Type: Application
    Filed: February 5, 2020
    Publication date: September 10, 2020
    Inventors: Brian S.J. BLAGG, Bhaskar Reddy KUSUMA, Teather SUNDSTROM
  • C-terminal HSP90 inhibitors
    Patent number: 10590157
    Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: March 17, 2020
    Assignee: UNIVERSITY OF KANSAS
    Inventors: Brian S. J. Blagg, Bhaskar Reddy Kusuma, Teather Sundstrom
  • C-TERMINAL HSP90 INHIBITORS
    Publication number: 20190023730
    Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
    Type: Application
    Filed: June 26, 2018
    Publication date: January 24, 2019
    Inventors: Brian S.J. BLAGG, Bhaskar Reddy KUSUMA, Teather SUNDSTROM
  • C-terminal Hsp90 inhibitors
    Patent number: 10030041
    Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
    Type: Grant
    Filed: August 3, 2016
    Date of Patent: July 24, 2018
    Assignee: UNIVERSITY OF KANSAS
    Inventors: Brian S. J. Blagg, Bhaskar Reddy Kusuma, Teather Sundstrom
  • C-TERMINAL HSP90 INHIBITORS
    Publication number: 20170051000
    Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
    Type: Application
    Filed: August 3, 2016
    Publication date: February 23, 2017
    Inventors: Brian S.J. BLAGG, Bhaskar Reddy KUSUMA, Teather SUNDSTROM
  • C-terminal HSP90 inhibitors
    Patent number: 9422320
    Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
    Type: Grant
    Filed: February 8, 2013
    Date of Patent: August 23, 2016
    Assignee: UNIVERSITY OF KANSAS
    Inventors: Brian S. J. Blagg, Bhaskar Reddy Kusuma, Teather Sundstrom
  • Dynamic inhibitors of heat shock protein 90
    Patent number: 9056104
    Abstract: An inhibitor of heat shock protein 90 (HSP90) can include a coumermycin A1 analog having a structure that inhibits HSP90 greater than coumermycin A1. That is, the coumermycin A1 analog is not coumermycin A1. The coumermycin A1 analog can have an antiproliferative biological activity, which can be superior to coumermycin A1. The activity can include the coumermycin A1 analog inhibiting a C-terminus of HSP90.
    Type: Grant
    Filed: May 16, 2012
    Date of Patent: June 16, 2015
    Assignee: THE UNIVERSITY OF KANSAS
    Inventors: Brian S. J. Blagg, Bhaskar Reddy Kusuma
  • C-TERMINAL HSP90 INHIBITORS
    Publication number: 20150057240
    Abstract: Hsp90 C-terminal inhibitors and pharmaceutical compositions containing such compounds are provided. The compounds of the disclosure are useful for the treatment and/or prevention of neurodegenerative disorders such as diabetic peripheral neuropathy.
    Type: Application
    Filed: February 8, 2013
    Publication date: February 26, 2015
    Inventors: Brian S. J. Blagg, Bhaskar Reddy Kusuma, Teather Sundstrom
  • DYNAMIC INHIBITORS OF HEAT SHOCK PROTEIN 90
    Publication number: 20120309702
    Abstract: An inhibitor of heat shock protein 90 (HSP90) can include a coumermycin A1 analog having a structure that inhibits HSP90 greater than coumermycin A1. That is, the coumermycin A1 analog is not coumermycin A1. The coumermycin A1 analog can have an antiproliferative biological activity, which can be superior to coumermycin A1. The activity can include the coumermycin A1 analog inhibiting a C-terminus of HSP90.
    Type: Application
    Filed: May 16, 2012
    Publication date: December 6, 2012
    Applicant: UNIVERSITY OF KANSAS
    Inventors: Brian S.J. Blagg, Bhaskar Reddy Kusuma