Patents by Inventor Bhaskara Reddy Madina

Bhaskara Reddy Madina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS OF USE OF ONCOLYTIC VIRUS LIKE VESICLES
    Publication number: 20230063041
    Abstract: The present invention relates to high-titer hybrid vims vectors which produce virus-like vesicle (VLVs) and compositions and methods thereof for targeting a malignancy or infectious disease. VLVs are a capsid-free, self-replicating artificial virus platform carrying positive-strand capped and polyadenylated RNA encoding an in vitro evolved Semliki Forest vims (SFV) RNA-dependent RNA replicase and the vesicular stomatitis virus (VSV) glycoprotein. The VLVs of the present invention and pharmaceutical compositions thereof encode for polynucleotide and/or polypeptide therapeutic agents useful in methods for the treatment, prophylaxis, and prevention of malignancies and infectious diseases.
    Type: Application
    Filed: January 8, 2021
    Publication date: March 2, 2023
    Applicant: Carogen Corporation
    Inventors: Bijan Almassian, Valerian Nakaar, Xianyong Ma, Bhaskara Reddy Madina, Kepeng Wang, Timur Yarovinsky