Abstract: The present invention relates to improved topical composition of Colchicine or a pharmaceutically acceptable salt thereof as an active agent and, process of preparing such improved topical composition. The invention also relates to the use of said improved topical composition for prophylaxis and the treatment of acute gout flares.

Abstract: The present disclosure relates to the ready to use intravenous infusion of Brivaracetam or salt thereof. The ready to use intravenous infusion of Brivaracetam or salt thereof provides longer stability, which can be administered for longer period of time, with direct use without prior dilution, which saves time for dilution in case of emergency, with better ease of handling and which is efficacious; provide better patient compliance in the treatment of seizures.

Abstract: The present invention relates to Suprabioavailable oral composition of Pirfenidone or salt thereof when compared with reference product of Pirfenidone capsule [267 mg] and tablet [267 mg and 801 mg] for the treatment of idiopathic pulmonary fibrosis (IPF). The Suprabioavailable oral composition of Pirfenidone or salt thereof provides at least 5% dose reduction which minimizes adverse effects and provides more efficacy with better patient compliance in the treatment of idiopathic pulmonary fibrosis.

Abstract: The present disclosure relates to the intranasal drug delivery system or composition of Brivaracetam or salt thereof. The nasal drug delivery Brivaracetam or salt thereof preferably in the form of Nasal sprays provide more bioavailability better onset of action, lesser adverse effects; better ease of self-administration and better patient compliance in the treatment of partial-onset seizures.

Abstract: The present invention relates to antifungal cuticle oil composition comprising Efinaconazole or Tavaborole or Terbinafine or salt thereof in the treatment of onychomycosis. The topical antifungal cuticle oil according to present invention provides better penetration and application at affected site results in better efficacy and patient compliance in the treatment of onychomycosis. The said composition also combat fungus of nail, cuticle, nail bed area and skin surrounding nail, protect and nourish the nails which got brittle, inflamed, painful and white to yellow in onychomycosis.