Patents by Inventor Bholanath PAUL

Bholanath PAUL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted cathechols as inhibitors of IL-4 and IL-5 for the treatment of bronchial asthma
    Patent number: 9302967
    Abstract: The present invention relates to compounds of general formula 1 for the treatment of bronchial asthma by inhibition of IL-4 or IL-5 pathway inhibition. The present invention also relates to the use of compound of general formula 1 for the treatment of bronchial by inhibition of IL-4 or IL-5 pathway. The present invention also relates to the method of treating asthma by inhibition of IL-4 or IL-5 pathway by administration of compound or said composition through oral, intranasal, route or by inhalation to a mammal in need thereof. Compound of general formula 1 may be used for reducing perivascular and peribronchial inflammation.
    Type: Grant
    Filed: April 11, 2012
    Date of Patent: April 5, 2016
    Assignee: Council of Scientific & Industrial Research
    Inventors: Santu Bandyopadhyay, Balaram Ghosh, Parasuraman Jaisankar, Bikas Chandra Pal, Siddhartha Roy, Bholanath Paul, Arjun Ram, Ulaganathan Mabalirajan, Nahid Ali, Arun Bandopadhyay, Aditya Konar, Jayashree Bagchi Chakraborty, Indrani Choudhury Mukherjee, Jaydeep Chaudhuri, Sanjit Kumar Mahato, Anirban Manna, Roma Sinha, Pradyot Bhattacharya, Jayaraman Vinayagam, Deba Prasad Jana, Sushovan Chowdhury
  • Triazine-aryl-bis-indoles and process for preparation thereof
    Patent number: 9085559
    Abstract: A novel heterocyclic compound belonging to ‘triazine-aryl-bis-indoles’, useful for the treatment of asthma. The pathway by which this compound inhibits asthma is also demonstrated. The present invention also provides a process for the preparation of above compounds and their derivatives are presented.
    Type: Grant
    Filed: December 31, 2010
    Date of Patent: July 21, 2015
    Assignee: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Vasanta Madhava Sharma Gangavaram, Jhillu Singh Yadav, Radha Krishna Palakodety, Arun Bandyopadhyay, Siddhartha Roy, Santu Bandyopadhyay, Rakesh Kamal Johri, Subhash Chander Sharma, Balaram Ghosh, Mabalirajan Ulaganathan, Sakshi Balwani, Bholanath Paul, Ashok Kumar Saxena
  • SUBSTITUTED CATHECHOLS AS INHIBITORS OF IL-4 AND IL-5 FOR THE TREATMENT BRONCHIAL ASTHMA
    Publication number: 20140135393
    Abstract: The present invention relates to compounds of general formula 1 for the treatment of bronchial asthma by inhibition of IL-4 or IL-5 pathway inhibition. The present invention also relates to the use of compound of general formula 1 for the treatment of bronchial by inhibition of IL-4 or IL-5 pathway. The present invention also relates to the method of treating asthma by inhibition of IL-4 or IL-5 pathway by administration of compound or said composition through oral, intranasal, route or by inhalation to a mammal in need thereof. Compound of general formula 1 may be used for reducing perivascular and peribronchial inflammation.
    Type: Application
    Filed: April 11, 2012
    Publication date: May 15, 2014
    Applicant: Council of Scientific & Industrial Research
    Inventors: Santu Bandyopadhyay, Balaram Ghosh, Parasuraman Jaisankar, Bikas Chandra Pal, Siddhartha Roy, Balaram Ghosh, Parasuraman Jaisankar, Bikas Pal, Nahid Ali, Siddhartha Roy, Bholanath Paul, Arjun Ram, Siddhartha Roy, Bholanath Paul, Arjun Ram, Ulaganathan Mabalirajan, Nahid Ali, Arun Bandopadhyay, Aditya Konar, Jayashree Bagchi Chakraborty, Indrani Chowdhury Mukherjee, Jaydeep Chaudhuri, Sanjit Kumar Mahato, Anirban Manna, Roma Sinha, Prayot Bhattacharya, Jayaraman Vinayagam, Deba Prasad Jana, Sushovan Chowdhury
  • Method for treatment of bronchial asthma
    Patent number: 8519154
    Abstract: The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthma and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients. Structural formula of the compounds of general formula 1 useful as phosphodiesterase-4 (PDE-4) enzyme inhibitors, inhibitor for signalling molecule for the treatment of asthma and asthma related diseases is given below: wherein R1=H or OCH3; R2?CH3 or CHO; R3?H or OCH3; R4?H or OCH3 Herbal route for the isolation of compound of general formula 1 from the bark of plant Murraya Koenigii and chemical route for the preparation of such compounds from basic compounds such as vanillin is also reported.
    Type: Grant
    Filed: February 3, 2012
    Date of Patent: August 27, 2013
    Assignee: Council of Scientific & Industrial Research
    Inventors: Sibabrata Mukhopadhyay, Mumu Chakraborty, Tulika Mukherjee, Arun Bandyopadhyay, Dipak Kar, Tanima Banerjee, Aditya Konar, Debaprasad Jana, Siddhartha Roy, Santu Bandyopadhyay, Balram Ghosh, Mabalirajan Ulaganathan, Rakesh Kamal Johri, Subhash Chander Sharma, Gurdarshan Singh, Bholanath Paul, Vasanta Madhava Sharma Gangavaram, Jhillu Singh Yadav, Radha Krishna Palakodety
  • TRIAZINE-ARYL-BIS-INDOLES AND PROCESS FOR PREPARATION THEREOF
    Publication number: 20120283263
    Abstract: A novel heterocyclic compound belonging to ‘triazine-aryl-bis-indoles’, useful for the treatment of asthma. The pathway by which this compound inhibits asthma is also demonstrated. The present invention also provides a process for the preparation of above compounds and their derivatives are presented.
    Type: Application
    Filed: December 31, 2010
    Publication date: November 8, 2012
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Vasanta Madhava Sharma Gangavaram, Jhillu Singh Yadav, Radha Krishna Palakodety, Arun Bandyopadhyay, Siddhartha Roy, Santu Bandyopadhyay, Rakesh Kamal Johri, Subhash Chander Sharma, Balaram Ghosh, Mabalirajan Ulaganathan, Sakshi Balwani, Bholanath Paul, Ashok Kumar Saxena
  • METHOD FOR TREATMENT OF BRONCHIAL ASTHMA
    Publication number: 20120202868
    Abstract: The present invention relates to a method for the treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD) comprising administering to the patient suffering from asthama and COPD an effective dose of carbazole derivatives or salt thereof, optionally along with pharmaceutically acceptable excipients. Structural formula of the compounds of general formula 1 useful as phosphodiesterase-4 (PDE-4) enzyme inhibitors, inhibitor for signalling molecule for the treatment of asthma and asthma related diseases is given below: wherein R1=H or OCH3; R2?CH3 or CHO; R3?H or OCH3; R4?H or OCH3 Herbal route for the isolation of compound of general formula 1 from the bark of plant Murraya Koenigii and chemical route for the preparation of such compounds from basic compounds such as vanillin is also reported.
    Type: Application
    Filed: February 3, 2012
    Publication date: August 9, 2012
    Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
    Inventors: Sibabrata MUKHOPADHYAY, Mumu CHAKRABORTY, Tulika MUKHERJEE, Arun BANDYOPADHYAY, Dipak KAR, Tanima BANERJEE, Aditya KONAR, Debaprasad JANA, Siddhartha ROY, Santu BANDYOPADHYAY, Balram GHOSH, Mabalirajan ULAGANATHAN, Rakesh Kamal JOHRI, Subhash Chander SHARMA, Gurdarshan SINGH, Bholanath PAUL, Vasanta Madhava Sharma GANGAVARAM, Jhillu Singh YADAV, Radha Krishna PALAKODETY