Abstract: A system for radiation therapy includes an ionizing radiation source for producing a beam oriented along an axis aligned with a target volume for delivering ionizing radiation to the target volume along a beam path and at a dose rate, wherein the beam includes a soft spectrum and a hard spectrum. The system also includes a filter arranged within the beam path and including a central aperture that is free of beam-filtering material, wherein the central aperture is surrounded by a beam-filtering material having a thickness dimension selected and positioned in the beam path to highly attenuate the soft spectrum of the beam to reduces external scatter of the beam and allow a majority of the hard spectrum of the beam to pass through the central aperture unfiltered. The beam path is free of beam-filtering material arranged to attenuate a central portion of the beam.

Abstract: A system and method for analyzing medical images of a subject includes acquiring the medical images of the subject and texture images. A computer system determines, using the medical images and the texture feature images, a plurality of segmentation surfaces by iteratively adjusting a relationship between a region growing algorithm that selects a region of interest (ROI) to determine a given segmentation surface and cost function for evaluating the given segmentation surface. The computer system generates a report using the plurality of segmentation surfaces indicating at least boundaries between anatomical structures with functional differences in the medical images.

Abstract: A system for radiation therapy includes an ionizing radiation source for producing a beam oriented along an axis aligned with a target volume for delivering ionizing radiation to the target volume along a beam path and at a dose rate, wherein the beam includes a soft spectrum and a hard spectrum. The system also includes a filter arranged within the beam path and including a central aperture that is free of beam-filtering material, wherein the central aperture is surrounded by a beam-filtering material having a thickness dimension selected and positioned in the beam path to highly attenuate the soft spectrum of the beam to reduces external scatter of the beam and allow a majority of the hard spectrum of the beam to pass through the central aperture unfiltered. The beam path is free of beam-filtering material arranged to attenuate a central portion of the beam.

Abstract: A system and method for analyzing medical images of a subject includes acquiring the medical images of the subject and texture images. A computer system determines, using the medical images and the texture feature images, a plurality of segmentation surfaces by iteratively adjusting a relationship between a region growing algorithm that selects a region of interest (ROI) to determine a given segmentation surface and cost function for evaluating the given segmentation surface. The computer system generates a report using the plurality of segmentation surfaces indicating at least boundaries between anatomical structures with functional differences in the medical images.

Abstract: A stand-alone calculator enables multi energy electron beam treatments with standard single beam electron beam radiotherapy equipment thereby providing improved dose profiles. By employing user defined depth-dose profiles, the calculator may work with a wide variety of existing standard electron beam radiotherapy systems.