Abstract: The invention provides compositions of anti-PD-1 antibodies or antigen-binding fragments thereof with less than or equal to about 3.0% oxidation of Met105 in the CDRH3 heavy chain region, and methods of obtaining the purified compositions. The invention also provides compositions comprising anti-PD-1 antibody main species and acidic species thereof, wherein the amount of acidic species is about 1.0-12.0%.

Abstract: A method includes monitoring environmental conditions surrounding a moving vehicle, using an on-board sensor of the moving vehicle, detecting that at least one of the environmental conditions surrounding the moving vehicle is likely to impair visibility for a driver of the moving vehicle, based on an output of the on-board sensor, acquiring static map data for a location surrounding the moving vehicle, acquiring real time sensor data for the location surrounding the moving vehicle, where the real time sensor data comprises outputs of a plurality of on-board sensors of a plurality of other vehicles, generating an augmented reality view of the location surrounding the moving vehicle, using the static map data, the real time sensor data, and the output of the on-board sensor, and displaying the augmented reality view of the location surrounding the moving vehicle on a display within the moving vehicle.

Abstract: A method includes monitoring environmental conditions surrounding a moving vehicle, using an on-board sensor of the moving vehicle, detecting that at least one of the environmental conditions surrounding the moving vehicle is likely to impair visibility for a driver of the moving vehicle, based on an output of the on-board sensor, acquiring static map data for a location surrounding the moving vehicle, acquiring real time sensor data for the location surrounding the moving vehicle, where the real time sensor data comprises outputs of a plurality of on-board sensors of a plurality of other vehicles, generating an augmented reality view of the location surrounding the moving vehicle, using the static map data, the real time sensor data, and the output of the on-board sensor, and displaying the augmented reality view of the location surrounding the moving vehicle on a display within the moving vehicle.

Abstract: A method includes monitoring environmental conditions surrounding a moving vehicle, using an on-board sensor of the moving vehicle, detecting that at least one of the environmental conditions surrounding the moving vehicle is likely to impair visibility for a driver of the moving vehicle, based on an output of the on-board sensor, acquiring static map data for a location surrounding the moving vehicle, acquiring real time sensor data for the location surrounding the moving vehicle, where the real time sensor data comprises outputs of a plurality of on-board sensors of a plurality of other vehicles, generating an augmented reality view of the location surrounding the moving vehicle, using the static map data, the real time sensor data, and the output of the on-board sensor, and displaying the augmented reality view of the location surrounding the moving vehicle on a display within the moving vehicle.

Abstract: Aspects of the subject disclosure may include, for example, determining a group of users are participating in a communication session. Each user of the group of users are participating in the communication session with a communication device resulting in a group of communication devices. Further embodiments include receiving a request for a first meeting location for the group of users to meet, and identifying a device location for each of the group of communication devices resulting in a group of device locations. Additional embodiments can include identifying the first meeting location based on the group of meeting locations, and providing the first meeting location to each communication device of the group of communication devices, each communication device presents the first meeting location during the communication session. Other embodiments are disclosed.

Abstract: The concepts and technologies disclosed herein are directed to incentivized rental vehicle return. According to one aspect disclosed herein, a user device can determine a return location and a return date for a rental vehicle that is subject to an existing vehicle rental agreement between a user and a rental company. The user device can calculate a return on investment (“ROI”) for the return location and the return date in consideration of an incentive to be provided to the user, compare the ROI to an initial ROI based on the existing vehicle rental agreement, and determine whether the ROI is greater than the initial ROI. The user device also can present, to the user, a return option that identifies the return location, the return date, and the incentive when the ROI is greater than the initial ROI.

Abstract: Architectures and techniques are presented that can leverage safety metrics such as crime or health-based statistics at various geographic locations to supplement or improve navigation application searches or results. For example, navigation search results can be tagged with safety metric alert indicia if a location associated with a search result (or a location associated with a path to the point of interest of the search result) does not satisfy a defined safety metric. As another example, navigation search results can be generated as a function of the defined safety metric rather than merely as a function of distance, thereby operating to filter results that do not satisfy the safety metric, whether filtering a particular point of interest or filtering a path to a selected point of interest.

Abstract: Aspects of the subject disclosure may include, for example, obtaining a first network parameter associated with a first network device and obtaining a second network parameter associated with a second network device. Further embodiments include determining that the first network device is less congested than the second network device based on the first network parameter and the second network parameter resulting in a first determination. Additional embodiments include amplifying a first wireless signal based on the first determination and in response to receiving the first wireless signal from the first network device resulting in a first amplified wireless signal, and transmitting the first amplified wireless signal Other embodiments are disclosed.

Abstract: Aspects of the subject disclosure may include, for example, obtaining a first network parameter associated with a first network device and obtaining a second network parameter associated with a second network device. Further embodiments include determining that the first network device is less congested than the second network device based on the first network parameter and the second network parameter resulting in a first determination. Additional embodiments include amplifying a first wireless signal based on the first determination and in response to receiving the first wireless signal from the first network device resulting in a first amplified wireless signal, and transmitting the first amplified wireless signal Other embodiments are disclosed.

Abstract: The present invention relates to Polysaccharide Size-Reduction Monitoring Methods useful for the non-invasive, and accurate monitoring of the progress of a polysaccharide size-reduction process.

Abstract: Aspects of the subject disclosure may include, for example, a method that include combining an offer with media content to generate a notice within a portion of the media content, providing the notice in the designated portions of the media content with the notice during a media content presentation at equipment of a user, receiving an indication of interest in the portion, retrieving marketing information for the portion of the media content based on the user profile including location based information, time based information, and activity information, monitoring an activity of the mobile communication device to determine when the mobile communication device information satisfies a location, time, and activity information that matches the marketing information and determining a communication for the user based on the marketing information and the monitoring of the activity of the mobile communication device. Other embodiments are disclosed.

Abstract: A system for navigation and ride hailing that provides options for navigating traffic through express lanes or the like. Information, such as express lane profile information, toll price information for the express lane during a period, and traffic information along one or more paths may be used to determine the fastest options along to a destination at different toll price points.

Abstract: The present invention relates to a method of measuring at least one product quality attributes, including critical quality attributes (e.g., oxidation, C-terminal lysine, aggregation, N-terminal glutamine cyclization.) by an online liquid chromatography system, wherein the liquid chromatography system is running a hydrophobic interaction chromatography (HIC) method.

Abstract: A system for navigation and ride hailing that provides options for navigating traffic through express lanes or the like. Information, such as express lane profile information, toll price information for the express lane during a period, and traffic information along one or more paths may be used to determine the fastest options along to a destination at different toll price points.

Abstract: Aspects of the subject disclosure may include, for example, receiving a first user input that identifies a first trigger phrase to be monitored for in a first virtual meeting being facilitated by the device, monitoring, responsive to the receiving the first user input, the first virtual meeting for occurrences of the first trigger phrase, determining that a user of the device is currently engaged in a second virtual meeting being facilitated by the device, detecting, based on the monitoring, an occurrence of the first trigger phrase in the first virtual meeting, and causing a first notification regarding the occurrence of the first trigger phrase in the first virtual meeting to be outputted, wherein the causing is based on the determining that the user of the device is currently engaged in the second virtual meeting. Other embodiments are disclosed.

Abstract: A method includes detecting a location of a user device, receiving a menu from a restaurant proximate to the location, accessing information from a data base associated with a user, wherein the information includes recent or expected workout plans, personal preferences, order history, dietary restrictions and nutritional goals, recommending a plurality of food items from the menu based on the location and the information, categorizing the recommended food items, receiving an order for a food item from the recommended food items from the user device, causing the food order to be ordered through a food delivery application.

Abstract: Aspects of the subject disclosure may include, for example, obtaining social media information associated with a user, and obtaining financial information associated with the user. Further embodiments include generating a group of keywords based on the social media information and the financial information, and receiving a message for the user. Additional embodiments include blocking sending of the message to a communication device associated with the user in response to detecting a first keyword from the group of keywords in the message, and sending a notification to the communication device associated with the user that the message was blocked. Other embodiments are disclosed.

Abstract: Aspects of the subject disclosure may include, for example, receiving a first user input that identifies a first trigger phrase to be monitored for in a first virtual meeting being facilitated by the device, monitoring, responsive to the receiving the first user input, the first virtual meeting for occurrences of the first trigger phrase, determining that a user of the device is currently engaged in a second virtual meeting being facilitated by the device, detecting, based on the monitoring, an occurrence of the first trigger phrase in the first virtual meeting, and causing a first notification regarding the occurrence of the first trigger phrase in the first virtual meeting to be outputted, wherein the causing is based on the determining that the user of the device is currently engaged in the second virtual meeting. Other embodiments are disclosed.

Abstract: Aspects of the subject disclosure may include, for example, receiving a first user input that identifies a first trigger phrase to be monitored for in a first virtual meeting being facilitated by the device, monitoring, responsive to the receiving the first user input, the first virtual meeting for occurrences of the first trigger phrase, determining that a user of the device is currently engaged in a second virtual meeting being facilitated by the device, detecting, based on the monitoring, an occurrence of the first trigger phrase in the first virtual meeting, and causing a first notification regarding the occurrence of the first trigger phrase in the first virtual meeting to be outputted, wherein the causing is based on the determining that the user of the device is currently engaged in the second virtual meeting. Other embodiments are disclosed.

Abstract: Aspects of the subject disclosure may include, for example, obtaining, from a content system, transaction information associated with a first digital content item, where the transaction information relates to a purchase of the first digital content item by a first user, processing, using a blockchain network, the transaction information to validate the purchase, based on validating the purchase, generating, using the blockchain network, a first block of data, adding, using the blockchain network, the first block of data to a blockchain, deriving, a first unique identifier for the first digital content item, and providing the first unique identifier to the content system, where the providing the first unique identifier causes the content system to associate the first unique identifier with a first user account associated with the first user, such that the first user is permitted to access the first digital content item. Other embodiments are disclosed.