Abstract: The present invention involves a novel method for treatment of chronic kidney disease comprising administering a compound that induces a stress protein response in a patient, and administering a potent antioxidant if the patent's response is below a predefined level. It also involves a quantitative measure for determining a patient's antioxidant reserve capacity.

Abstract: The present invention involves a novel method for treatment of chronic kidney disease comprising administering a compound that induces a stress protein response in a patient, and administering a potent antioxidant if the patent's response is below a predefined level. It also involves a quantitative measure for determining a patient's antioxidant reserve capacity.

Abstract: Prediction logic analyzes previous data usage activities of a customer process running on a host machine to generate a first prediction indicating that the customer process will request a first data set at a first time. The prediction logic retrieves the first data set from long-term storage and loads the first data set into memory on the host machine in advance of the first time in order to provide the customer process with access to first data set in the memory during a period between the first time and a second time. The prediction logic further generates a second prediction indicating that the customer process will not access the first data set for a threshold period of time after the second time and stores the first data set in the long-term storage at the second time.

Abstract: In some embodiments, a system for providing DisplayPort communication over an extension medium is provided. The system comprises an upstream facing port device (UFP device) and a downstream facing port device (DFP device). The UFP device is configured to conduct link training with a DisplayPort source device using first DisplayPort configuration data (DPCD). The DFP device is configured to conduct link training with the DisplayPort sink device using second DPCD different from the first DPCD. The UFP device is configured to extract video data from DisplayPort data received from the DisplayPort source device and transmit the video data to the DFP device. The DFP device is configured to receive the video data, generate DisplayPort data as specified by the second DPCD, and transmit the generated DisplayPort data to the DisplayPort sink device as specified by the second DPCD.

Abstract: A system for blockchain based digital therapeutic devices to predict food-drug constituent interaction. This uses a set of Algorithms to collect, process, cluster, structure and analyze User input data, and a set of Algorithms to collect, process, cluster, structure and analyze Scientific Modules of Drug, Food data and associated literature. There is a also a set of Algorithms to establish credible correlation and relationship between input data sources by various advanced machines learning models to fetch the required outputs by processing, analyzing and structuring input data. A set of Algorithms is used to interact the user data with Drug-Food Scientific modules and Literature. Machine learning models to predict Drug-Food Interactions and learn user preferences and habits.

Abstract: A method for reserving access to a shared space through use of a blockchain and smart contracts includes: storing a blockchain including a plurality of blocks, each block including a block header and one or more blockchain data values, wherein one of the one or more blockchain data values included in one of the plurality of blocks includes a smart contract including at least an identifier and one or more terms; receiving a reservation request, wherein the reservation request includes at least the identifier, a reservation time, a public key of a cryptographic key pair, and a digital signature generated using the private key of the cryptographic key pair; validating the digital signature using the public key; executing the smart contract using the public key and the reservation time; and transmitting one or more data values to an internet-enabled device as part of the execution of the smart contract.

Abstract: A method of verifying the destination of a transaction between nodes in a network includes receiving transaction information corresponding to a transaction between the nodes, where the transaction information comprises a unique destination identifier and a destination name and where the unique destination identifier defines a destination account of the transaction; obtaining from a storage unit a set of names used in previous transactions to that destination account; determining at least one disparity value between the destination name and the set of names; and producing a destination verification value based on the at least one disparity value, wherein the destination verification value is used to verify whether the transaction between nodes should proceed.

Abstract: The inactivation of BK virus in patients diagnosed with BK virus, those receiving a kidney that is infected or suspected of being infected by BK virus, or in the transplanted kidney before, during, and/or after transplant surgery is described.

Abstract: A power take-off shaft system for an agricultural vehicle includes an output shaft with a socket for a power take-off shaft stub located at one end of the output shaft, wherein the power take-off shaft stub is arranged in the socket. A control valve is arranged in the output shaft and includes a valve bore extending axially from the socket into the output shaft. A first piston is adjustably arranged inside the valve bore in the output shaft, and a shifting element is adjustably controlled by the first piston. A first gearwheel and a second gearwheel are disposed in engagement with the output shaft via the shifting element such that the first piston is adjustable between a first position and a second position. The control valve includes a second piston arranged on the first piston, where the first piston is adjustable into a neutral position by the second piston.

Abstract: The present disclosure provides methods for the treatment of irritable bowel syndrome (IBS) and/or functional dyspepsia. In particular, the present disclosure provides methods for the treatment of irritable bowel syndrome (IBS) and/or functional dyspepsia through administration of antibodies that bind to human Siglec-8 or compositions comprising said antibodies. The present disclosure also provides articles of manufacture or kits comprising antibodies that bind to human Siglec-8 for the treatment of irritable bowel syndrome (IBS) and/or functional dyspepsia.

Abstract: A power take-off shaft system includes an output shaft with a socket for a power take-off shaft stub located at one end of the output shaft. A control valve is arranged in the output shaft and includes a valve bore extending axially from the socket into the output shaft. A first piston is adjustably arranged inside the valve bore in the output shaft, and a shifting element is adjustably controlled by the first piston. A first gearwheel and a second gearwheel are disposed in engagement with the output shaft via the shifting element such that the first piston moves between a first position and a second position. The control valve includes a second piston arranged on the first piston, and the second piston is adjustable such that movement of the first piston into the second position is blocked by the second piston.

Abstract: The present disclosure provides methods and kits suitable for administering a composition comprising an antibody that binds to human Siglec-8, e.g., to a human individual in need thereof. In some embodiments, a corticosteroid is administered to the individual at least 6 hours, at least 12 hours, or 12-24 hours prior to the first dose of the composition comprising the anti-Siglec-8 antibody.

Abstract: The present invention involves novel urea compositions for oral administration, that are useful for treatment or management of hyponatremia. Also disclosed are novel methods of making the urea compositions.

Abstract: A data handling device includes a plurality of data storage units that are adapted for long term redundant storage of data, generate heat during operation, and are mounted in a manner allowing cooling, and data accessing circuitry adapted determine information chunks relating to data to be stored such that a subset of the information chunks suffice for reproduction of the data, select several of the plurality of data storage units, write the information chunks onto the selected data storage units, determine from which of the selected data storage units to retrieve information chunks based on temperatures of the data storage units to reproduce the data, where at least some of the subset of data storage units are mounted to be cooled by a common vertical air.

Abstract: The present disclosure provides methods for the treatment of mast cell gastritis, mast cell esophagitis, mast cell colitis, mast cell enteritis, mast cell duodenitis, and/or mast cell gastroenteritis. In particular, the present disclosure provides methods for the treatment of mast cell gastritis, mast cell esophagitis, mast cell colitis, mast cell enteritis, mast cell duodenitis, and/or mast cell gastroenteritis through administration of antibodies that bind to human Siglec-8 or compositions comprising said antibodies. The present disclosure also provides articles of manufacture or kits comprising antibodies that bind to human Siglec-8 for the treatment of mast cell gastritis, mast cell esophagitis, mast cell colitis, mast cell enteritis, mast cell duodenitis, and/or mast cell gastroenteritis.

Abstract: The present invention involves novel urea compositions for oral administration, that are useful for treatment or management of hyponatremia. Also disclosed are novel methods of making the urea compositions.

Abstract: In some embodiments, a system for providing DisplayPort communication over an extension medium is provided. The system comprises an upstream facing port device (UFP device) and a downstream facing port device (DFP device). The UFP device is configured to conduct link training with a DisplayPort source device using first DisplayPort configuration data (DPCD). The DFP device is configured to conduct link training with the DisplayPort sink device using second DPCD different from the first DPCD. The UFP device is configured to extract video data from DisplayPort data received from the DisplayPort source device and transmit the video data to the DFP device. The DFP device is configured to receive the video data, generate DisplayPort data as specified by the second DPCD, and transmit the generated DisplayPort data to the DisplayPort sink device as specified by the second DPCD.

Abstract: A method and a device for creating and training machine learning models is disclosed. In an embodiment, a method for training a machine learning model for identifying entities from data includes creating a first plurality of clusters from a first plurality of data samples in a first dataset and a second plurality of clusters from a second plurality of data samples in a second dataset. The method further includes determining a rank for each of the first plurality of clusters and a rank for each of the second plurality of clusters. The method includes retraining the machine learning model using at least one of the first plurality of clusters weighted based on the rank determined for each of the first plurality of clusters and at least one of the second plurality of clusters weighted based on the rank determined for each of the second plurality of clusters.

Abstract: A computer-implemented method and apparatus for facilitating a provisioning of advertisements to customers effects display of one or more advertisements on a Web domain. Each displayed advertisement is configured to offer advertisement related assistance to customers visiting the Web domain. A selection input provided by a customer on an advertisement is received. In response to the receipt of the selection input, the system facilitates customer engagement with a customer support representative associated with an enterprise related to the advertisement. The customer engagement facilitated through the advertisement is configured to provide the advertisement related assistance to the customer.

Abstract: The present invention involves a novel method for treatment of coronavirus infection, including SARS-COV-2. The method comprises administering stannous protoporphyrin and/or cyanocobalamin to a human patient at risk for developing complications from coronavirus infection. The method is particularly useful where a patient has been diagnosed with coronavirus infection or has been exposed to coronavirus but has not developed symptoms of coronavirus infection.