Patents by Inventor Bianca A. Thomae

Bianca A. Thomae has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfotransferase 1E1 sequence variants
    Patent number: 8048662
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to cancer also are described.
    Type: Grant
    Filed: April 5, 2011
    Date of Patent: November 1, 2011
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Araba A. Adjei, Eric D. Wieben, Richard M. Weinshilboum, Bianca A. Thomae
  • SULFOTRANSFERASE 1E1 SEQUENCE VARIANTS
    Publication number: 20110244547
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to cancer also are described.
    Type: Application
    Filed: April 5, 2011
    Publication date: October 6, 2011
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Araba A. Adjei, Eric D. Wieben, Richard M. Weinshilboum, Bianca A. Thomae
  • Sulfotransferase 1E1 sequence variants
    Patent number: 7943355
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to cancer also are described.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: May 17, 2011
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Araba A Adjei, Eric D Wieben, Richard M Weinshilboum, Bianca A Thomae
  • SULFOTRANSFERASE 1E1 SEQUENCE VARIANTS
    Publication number: 20110014678
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to cancer also are described.
    Type: Application
    Filed: August 18, 2010
    Publication date: January 20, 2011
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Araba A. Adjei, Eric D. Wieben, Richard M. Weinshilboum, Bianca A. Thomae
  • Sulfotransferase 2B1 pharmacogenetics
    Patent number: 7820805
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as are sulfotransferase allozymes. Methods for determining the sulfonator status of a subject also are described. In addition, methods for predicting the therapeutic efficacy of a compound in a subject are described, as are methods for estimating the dose of a compound to be administered to a subject.
    Type: Grant
    Filed: September 25, 2007
    Date of Patent: October 26, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Bianca A. Thomae, Eric D. Wieben, Richard M. Weinshilboum
  • Sulfotransferase 1E1 sequence variants
    Patent number: 7803921
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to cancer also are described.
    Type: Grant
    Filed: September 25, 2007
    Date of Patent: September 28, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Araba A. Adjei, Eric D. Wieben, Richard M. Weinshilboum, Bianca A. Thomae
  • Sulfotransferase 1A3 sequence variants
    Patent number: 7745185
    Abstract: Isolated sulfotransferase 1A3 nucleic acid molecules and polypeptides that include nucleotide sequence variants and amino acid sequence variants are described. Methods for determining predisposition to particular clinical conditions and methods for determining sulfonator status also are described.
    Type: Grant
    Filed: May 27, 2008
    Date of Patent: June 29, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Bianca A. Thomae, Eric D. Wieben, Richard M. Weinshilboum
  • Sulfotransferase SULT2A1 sequence variants
    Patent number: 7514215
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to a heart condition or cancer also are described.
    Type: Grant
    Filed: July 12, 2005
    Date of Patent: April 7, 2009
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Bianca A. Thomae, Eric D. Wieben, Richard M. Weinshilboum
  • Phenylethanolamine-N-methyltransferase sequence variants
    Patent number: 7482146
    Abstract: Isolated PNMT nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as PNMT allozymes. Methods for determining if a subject is predisposed to multiple sclerosis, early-onset Alzheimer's disease, or Parkinson's disease also are described.
    Type: Grant
    Filed: January 31, 2008
    Date of Patent: January 27, 2009
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Bianca A. Thomae, Eric D. Wieben, Richard M. Weinshilboum, Yuan Ji
  • Sulfotransferase 1A3 sequence variants
    Patent number: 7425624
    Abstract: Isolated sulfotransferase 1A3 nucleic acid molecules and polypeptides that include nucleotide sequence variants and amino acid sequence variants are described. Methods for determining predisposition to particular clinical conditions and methods for determining sulfonator status also are described.
    Type: Grant
    Filed: January 21, 2003
    Date of Patent: September 16, 2008
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Bianca A. Thomae, Eric D. Wieben, Richard M. Weinshilboum
  • SULFOTRANSFERASE 1E1 SEQUENCE VARIANTS
    Publication number: 20080182326
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to cancer also are described.
    Type: Application
    Filed: September 25, 2007
    Publication date: July 31, 2008
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Araba A. Adjei, Eric D. Wieben, Richard M. Weinshilboum, Bianca A. Thomae
  • SULFOTRANSFERASE 2B1 PHARMACOGENETICS
    Publication number: 20080118975
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as are sulfotransferase allozymes. Methods for determining the sulfonator status of a subject also are described. In addition, methods for predicting the therapeutic efficacy of a compound in a subject are described, as are methods for estimating the dose of a compound to be administered to a subject.
    Type: Application
    Filed: September 25, 2007
    Publication date: May 22, 2008
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Bianca A. Thomae, Eric D. Wieben, Richard M. Weinshilboum
  • Phenylethanolamine-N-methyltransferase sequence variants
    Patent number: 7371523
    Abstract: Isolated PNMT nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as PNMT allozymes. Methods for determining if a subject is predisposed to multiple sclerosis, early-onset Alzheimer's disease, or Parkinson's disease also are described.
    Type: Grant
    Filed: January 9, 2004
    Date of Patent: May 13, 2008
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Bianca A. Thomae, Eric D. Wieben, Richard M. Weinshilboum, Yuan Ji
  • Sulfotransferase 1E1 sequence variants
    Patent number: 7288641
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to cancer also are described.
    Type: Grant
    Filed: January 30, 2003
    Date of Patent: October 30, 2007
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Araba A. Adjei, Eric D. Wieben, Richard M. Weinshilboum, Bianca A. Thomae
  • Sulfotransferase 2B1 pharmacogenetics
    Patent number: 7288642
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as are sulfotransferase allozymes. Methods for determining the sulfonator status of a subject also are described. In addition, methods for predicting the therapeutic efficacy of a compound in a subject are described, as are methods for estimating the dose of a compound to be administered to a subject.
    Type: Grant
    Filed: November 6, 2003
    Date of Patent: October 30, 2007
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Bianca A. Thomae, Eric D. Wieben, Richard M. Weinshilboum
  • Arsenic methyltransferase sequence variants
    Patent number: 7250290
    Abstract: Isolated ASMT nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as ASMT allozymes. Methods for determining if a mammal is at risk for toxicity from acute or chronic arsenic exposure also are described.
    Type: Grant
    Filed: April 15, 2004
    Date of Patent: July 31, 2007
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Bianca A. Thomae, Eric D. Wieben, Richard M. Weinshilboum, Thomas C. Wood
  • Sulfotransferase SULT2A1 sequence variants
    Patent number: 7056731
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to a heart condition or cancer also are described.
    Type: Grant
    Filed: June 21, 2002
    Date of Patent: June 6, 2006
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Bianca A. Thomae, Eric D. Wieben, Richard M. Weinshilboum
  • Sulfotransferase SULT2A1 sequence variants
    Publication number: 20050277153
    Abstract: Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to a heart condition or cancer also are described.
    Type: Application
    Filed: July 12, 2005
    Publication date: December 15, 2005
    Inventors: Bianca Thomae, Eric Wieben, Richard Weinshilboum