Patents by Inventor Biancha Espinosa

Biancha Espinosa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENZYME INHIBITORS AND VIRAL INFECTION THERAPY
    Publication number: 20240109859
    Abstract: The invention relates to antiviral compounds, compositions comprising antiviral compounds, and methods of use. In particular, the antiviral compounds are cytidine triphosphate synthetase 1 (CTPS1) inhibitors that are effective in treating and/or preventing viral infection and in particular, SARS-CoV-2 infection and/or COVID-19 disease.
    Type: Application
    Filed: February 1, 2022
    Publication date: April 4, 2024
    Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Pinghui FENG, Chao ZHANG, Jun ZHAO, Biancha ESPINOSA, Chao QIN, Ali SAVAS, Youliang RAO, Ting-Yu WANG
  • NOVEL INHIBITORS OF GUANOSINE MONOPHOSPHATE SYNTHETASE AS THERAPEUTIC AGENTS
    Publication number: 20220048866
    Abstract: The invention provides a series of GMPS enzyme inhibitors. The invention includes potent GMPS inhibitors that specifically and covalently bind to GMPS, exhibit broad anti-cancer activity, block the infection efficiency of viruses, and have the potentials to suppress undesired immune responses. These novel inhibitors of GMPS, and their derivatives, have tremendous potentials to be used as therapeutic agents for the treatment of cancers, viral infection and immune disorders.
    Type: Application
    Filed: July 12, 2019
    Publication date: February 17, 2022
    Inventors: Chao Zhang, Feng Ni, Arunika Ekanayake, Biancha Espinosa