Patents by Inventor Bijan BOLDAJIPOUR

Bijan BOLDAJIPOUR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ROR1 TARGETING CHIMERIC ANTIGEN RECEPTOR
    Publication number: 20230022654
    Abstract: The present disclosure relates to polynucleotides encoding a chimeric polypeptide comprising a c-Jun polypeptide, a ROR1-binding protein, and a truncated EGF receptor. Also provided are cells (e.g., T cells) expressing CARs comprising a ROR1-binding protein and overexpressing a c-Jun polypeptide. Overexpression of c-Jun in CAR T cells confers improved properties, e.g., reducing or preventing exhaustion.
    Type: Application
    Filed: February 24, 2022
    Publication date: January 26, 2023
    Applicant: Lyell Immunopharma, Inc.
    Inventors: Spencer PARK, Queenie VONG, Blythe SATHER, Byoung RYU, Marc LAJOIE, Howell MOFFETT, Brian WEITZNER, Yun SONG, Scott BOYKEN, Neeraj SHARMA, Shobha POTLURI, Bijan BOLDAJIPOUR