Patents by Inventor Bijan Ghaleh

Bijan Ghaleh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and pharmaceutical compositions for the treatment of ischemic conditions
    Patent number: 10322162
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of ischemic conditions. In particular, the present invention relates to a method of treating an ischemic condition in a subject in need thereof comprising administering the subject with a polypeptide comprising an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the amino acid residue at position 186 to the amino acid residue at position 406 in SEQ ID NO: 1.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: June 18, 2019
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), COLLEGE DE FRANCE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS-EST CRETEIL VAL DE MARNE, ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP), ECOLE NATIONALE VETERINAIRE D'ALFORT (ENVA)
    Inventors: Stéphane Germain, Alain Berdeaux, Renaud Tissier, Bijan Ghaleh-Marzban, Catherine Monnot, Ariane Galaup
  • Methods for treating myocardial infarction comprising administering sonic hedgehog
    Patent number: 9987327
    Abstract: The present invention relates to methods and pharmaceutical compositions for cardioprotection of subjects who experienced a myocardial infarction. In particular, the present invention relates to a ligand of the sonic hedgehog signaling pathway for use in the cardioprotection of a subject who experienced a myocardial infarction.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: June 5, 2018
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE DE MONTPELLIER, ASSITANCE PUBLIQUE—HOPITAUX DE PARIS, UNIVERSITE PARIS EST CRETEIL VAL DE MARNE, UNIVERSITE D'ANGERS
    Inventors: Alain Lacampagne, Jerome Thireau, Olivier Cazorla, Jean-Yves Le Guennec, Jeremy Fauconnier, Maria del Carmen Martinez, Ramaroson Andriantsitohaina, Bijan Ghaleh-Marzban, Raffaella Soleti
  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF ISCHEMIC CONDITIONS
    Publication number: 20180000892
    Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of ischemic conditions. In particular, the present invention relates to a method of treating an ischemic condition in a subject in need thereof comprising administering the subject with a polypeptide comprising an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the amino acid residue at position 186 to the amino acid residue at position 406 in SEQ ID NO: 1.
    Type: Application
    Filed: January 6, 2016
    Publication date: January 4, 2018
    Inventors: Stéphane GERMAIN, Alain BERDEAUX, Renaud TISSIER, Bijan GHALEH-MARZBAN, Catherine MONNOT, Ariane GALAUP
  • Methods and Pharmaceutical Composition for the Preservation of Vascular Endothelial Cell Barrier Integrity
    Publication number: 20170313751
    Abstract: The invention relates to an ANGPTL4 polypeptide for use in the preservation of vascular endothelial cell barrier integrity and reduction in no-reflow phenomenon with myocardial infarction.
    Type: Application
    Filed: July 18, 2017
    Publication date: November 2, 2017
    Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Stephane Germain, Ariane Galaup, Catherine Monnot, Renaud Tissier, Bijan Ghaleh, Alain Berdeaux
  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE CARDIOPROTECTION
    Publication number: 20170049854
    Abstract: The present invention relates to methods and pharmaceutical compositions for cardioprotection of subjects who experienced a myocardial infarction. In particular, the present invention relates to a ligand of the sonic hedgehog signaling pathway for use in the cardioprotection of a subject who experienced a myocardial infarction.
    Type: Application
    Filed: October 17, 2016
    Publication date: February 23, 2017
    Inventors: Alain LACAMPAGNE, Jerome THIREAU, Olivier CAZORLA, Jean-Yves LE GUENNEC, Jeremy FAUCONNIER, Maria del Carmen MARTINEZ, Ramaroson ANDRIANTSITOHAINA, Bijan GHALEH-MARZBAN, Raffaella SOLETI
  • Methods for treating myocardial infarction comprising administering sonic hedgehog
    Patent number: 9504732
    Abstract: The present invention relates to methods and pharmaceutical compositions for cardioprotection of subjects who experienced a myocardial infarction. In particular, the present invention relates to a ligand of the sonic hedgehog signaling pathway for use in the cardioprotection of a subject who experienced a myocardial infarction.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: November 29, 2016
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE DE MONTPELLIER, ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS, UNIVERSITE PARIS EST CRETEIL VAL DE MARNE
    Inventors: Alain Lacampagne, Jerome Thireau, Olivier Cazorla, Jean-Yves Le Guennec, Jeremy Fauconnier, Maria del Carmen Martinez, Ramaroson Andriantsitohaina, Bijan Ghaleh-Marzban, Raffaella Soleti
  • Methods and Pharmaceutical Composition for the Preservation of Vascular Endothelial Cell Barrier Integrity
    Publication number: 20150353618
    Abstract: The invention relates to an ANGPTL4 polypeptide for use in the preservation of vascular endothelial cell barrier integrity and reduction in no-reflow phenomenon with myocardial infarction.
    Type: Application
    Filed: August 11, 2015
    Publication date: December 10, 2015
    Applicant: INSERM (Institut National de la Sante et de la Recherche Medicale)
    Inventors: Stephane Germain, Galaup Ariane, Catherine Monnot, Renaud Tissier, Bijan Ghaleh, Alain Berdeaux
  • METHODS AND PHARMACEUTICAL COMPOSITIONS FOR THE CARDIOPROTECTION
    Publication number: 20150352182
    Abstract: The present invention relates to methods and pharmaceutical compositions for cardioprotection of subjects who experienced a myocardial infarction. In particular, the present invention relates to a ligand of the sonic hedgehog signaling pathway for use in the cardioprotection of a subject who experienced a myocardial infarction.
    Type: Application
    Filed: January 14, 2014
    Publication date: December 10, 2015
    Inventors: Alain LACAMPAGNE, Jerome THIREAU, Olivier CAZORLA, Jean-Yves LE GUENNEC, Jeremy FAUCONNIER, Maria del Carmen MARTINEZ, Ramaroson ANDRIANTSITOHAINA, Bijan GHALEH-MARZBAN, Raffaella SOLETI
  • METHODS AND PHARMACEUTICAL COMPOSITION FOR THE PRESERVATION OF VASCULAR ENDOTHELIAL CELL BARRIER INTEGRITY
    Publication number: 20130023473
    Abstract: The invention relates to an ANGPTL4 polypeptide for use in the preservation of vascular endothelial cell barrier integrity and reduction in no-reflow phenomenon with myocardial infarction.
    Type: Application
    Filed: January 19, 2011
    Publication date: January 24, 2013
    Inventors: Stephane Germain, Ariane Galaup, Catherine Monnot, Renaud Tissier, Bijan Ghaleh, Alain Berdeaux