Patents by Inventor Bijoyita Roy

Bijoyita Roy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of Thermostable RNA Polymerases to Produce RNAs Having Reduced Immunogenicity
    Publication number: 20220288240
    Abstract: Provided herein, among other things, is a method for producing an RNA product that has reduced immunogenicity. In some embodiments, the method involves transcribing a template DNA with a thermostable RNA polymerase at a temperature of greater than 44° C.
    Type: Application
    Filed: May 27, 2022
    Publication date: September 15, 2022
    Applicant: New England Biolabs, Inc.
    Inventors: Bijoyita Roy, G. B. Robb
  • Use of thermostable RNA polymerases to produce RNAs having reduced immunogenicity
    Patent number: 11376338
    Abstract: Provided herein, among other things, is a method for producing an RNA product that has reduced immunogenicity. In some embodiments, the method involves transcribing a template DNA with a thermostable RNA polymerase at a temperature of greater than 44° C.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: July 5, 2022
    Assignee: New England Biolabs, Inc.
    Inventors: Bijoyita Roy, G. B. Robb
  • Methods and Compositions for Increased Capping Efficiency of Transcribed RNA
    Publication number: 20210317496
    Abstract: Methods and compositions for capping RNA in an in vitro transcription mixture are provided that include a thermostable RNA polymerase variant and a cap analog such that when a DNA template is added to the mixture, and the mixture is then incubated under conditions for in vitro transcription, capped RNA is produced.
    Type: Application
    Filed: June 24, 2021
    Publication date: October 14, 2021
    Applicant: New England Biolabs, Inc.
    Inventors: Bijoyita Roy, Jennifer Ong
  • Methods and compositions for increasing capping efficiency of transcribed RNA
    Patent number: 11072808
    Abstract: Methods and compositions for capping RNA in an in vitro transcription mixture are provided that include a thermostable RNA polymerase variant and a cap analog such that when a DNA template is added to the mixture, and the mixture is then incubated under conditions for in vitro transcription, capped RNA is produced.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: July 27, 2021
    Assignee: New England Biolabs, Inc.
    Inventors: Bijoyita Roy, Jennifer Ong
  • Use of Thermostable RNA Polymerases to Produce RNAs Having Reduced Immunogenicity
    Publication number: 20210147836
    Abstract: Provided herein, among other things, is a method for producing an RNA product that has reduced immunogenicity. In some embodiments, the method involves transcribing a template DNA with a thermostable RNA polymerase at a temperature of greater than 44° C.
    Type: Application
    Filed: June 12, 2018
    Publication date: May 20, 2021
    Applicant: New England Biolabs, Inc.
    Inventors: Bijoyita Roy, G. B. Robb
  • Enzymatic RNA Capping Method
    Publication number: 20210054016
    Abstract: Provided herein is a method for efficiently capping RNA in vitro. In some embodiments the capping reaction may be done at high temperature using Vaccinia capping enzyme or a variant thereof. In other embodiments, the capping reactions may comprise a capping enzyme from a large virus of amoeba, e.g., Faustovirus, mimivirus or moumouvirus, or a variant thereof. Compositions and kits for practicing the method are also provided.
    Type: Application
    Filed: August 24, 2020
    Publication date: February 25, 2021
    Applicant: NEW ENGLAND BIOLABS, INC.
    Inventors: G. Brett Robb, Siu-Hong Chan, Bijoyita Roy
  • Methods and Compositions for Increasing Capping Efficiency of Transcribed RNA
    Publication number: 20200109425
    Abstract: Methods and compositions for capping RNA in an in vitro transcription mixture are provided that include a thermostable RNA polymerase variant and a cap analog such that when a DNA template is added to the mixture, and the mixture is then incubated under conditions for in vitro transcription, capped RNA is produced.
    Type: Application
    Filed: October 4, 2018
    Publication date: April 9, 2020
    Applicant: New England Biolabs, Inc.
    Inventors: Bijoyita Roy, Jennifer Ong
  • Use of thermostable RNA polymerases to produce RNAs having reduced immunogenicity
    Patent number: 10034951
    Abstract: Provided herein, among other things, is a method for producing an RNA product that has reduced immunogenicity without requiring removal of any dsRNA from the RNA product. In some embodiments, the method involves transcribing a template DNA with a thermostable RNA polymerase at a temperature of greater than 44° C.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: July 31, 2018
    Assignee: New England Biolabs, Inc.
    Inventors: Bijoyita Roy, G. B. Robb