Patents by Inventor Bikash Sahoo

Bikash Sahoo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipid nanodisc formation by acryloyl-based copolymers
    Patent number: 12050227
    Abstract: The disclosure generally relates generally to lipid nanodiscs, in particular to lipid nanodiscs formed from acryloyl-based copolymers. A lipid nanodisc according to the disclosure includes a lipid bilayer having a first hydrophilic face and a second hydrophilic face opposing the first hydrophilic face, and a hydrophobic edge between the opposing hydrophilic faces, and an acryloyl-based copolymer encircling the hydrophobic edge of the lipid bilayer. The acryloyl-based copolymer includes a first monomer unit having a pendant hydrophobic group and a second monomer unit having a pendant hydrophilic group. Methods of making and characterizing the lipid nanodiscs are also disclosed.
    Type: Grant
    Filed: April 17, 2019
    Date of Patent: July 30, 2024
    Assignees: Nara Institute of Science and Technology, THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Ayyalusamy Ramamoorthy, Thirupathi Ravula, Bikash Sahoo, Kazuma Yasuhara, Jin Arakida, Jun-Ichi Kikuchi
  • Lipid Nanodisc formation by Acryloyl-based copolymers
    Publication number: 20190346464
    Abstract: The disclosure generally relates generally to lipid nanodiscs, in particular to lipid nanodiscs formed from acryloyl-based copolymers. A lipid nanodisc according to the disclosure includes a lipid bilayer having a first hydrophilic face and a second hydrophilic face opposing the first hydrophilic face, and a hydrophobic edge between the opposing hydrophilic faces, and an acryloyl-based copolymer encircling the hydrophobic edge of the lipid bilayer. The acryloyl-based copolymer includes a first monomer unit having a pendant hydrophobic group and a second monomer unit having a pendant hydrophilic group. Methods of making and characterizing the lipid nanodiscs are also disclosed.
    Type: Application
    Filed: April 17, 2019
    Publication date: November 14, 2019
    Inventors: Ayyalusamy Ramamoorthy, Thirupathi Ravula, Bikash Sahoo, Kazuma Yasuhara, Jin Arakida, Jun-Ichi Kikuchi