Patents by Inventor Biljana Culjkovic Kraljacic

Biljana Culjkovic Kraljacic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination therapy using ribavirin as elF4E inhibitor
    Patent number: 10342817
    Abstract: The present invention relates to pharmaceutical compositions and combination therapies for treating patients having a neoplasm or a proliferative disorder, the combination comprises ribavirin, GDC-0449 and a chemotherapeutic agent, wherein said combination therapy overcomes resistance developed in patients during anti-neoplastic treatment. The present invention also provides a combination therapy for treating patients having leukemia.
    Type: Grant
    Filed: January 16, 2017
    Date of Patent: July 9, 2019
    Assignee: Universite de Montreal
    Inventors: Katherine Borden, Hiba Zahreddine, Biljana Culjkovic Kraljacic
  • Combination Therapy Using Ribavirin As eIF4E Inhibitor
    Publication number: 20170119809
    Abstract: The present invention relates to pharmaceutical compositions and combination therapies for treating patients having a neoplasm or a proliferative disorder, the combination comprises an inhibitor of the eIF4E gene product and a chemotherapeutic agent, wherein said combination therapy overcomes resistance developed in patients during anti-neoplastic treatment. The present invention also provides for the use of a combination therapy for treating patients having a neoplasm, a proliferative disorder, pre-neoplasm or a precancerous lesion, comprising an inhibitor of the eIF4E gene product, a chemotherapeutic agent, and a therapeutically effective amount of a hedgehog pathway inhibitor; and the method of using said combination therapy.
    Type: Application
    Filed: January 16, 2017
    Publication date: May 4, 2017
    Inventors: Katherine Borden, Hiba Zahreddine, Biljana Culjkovic Kraljacic
  • Combination therapy using ribavirin as eIF4E inhibitor
    Patent number: 9545416
    Abstract: The present invention relates to pharmaceutical compositions and combination therapies for treating patients having a neoplasm or a proliferative disorder, the combination comprises an inhibitor of the e1F4E gene product, such as ribavirin, and a chemotherapeutic agent, such as cytarabine, wherein said combination therapy overcomes resistance developed in patients during anti-neoplastic treatment. The present invention also provides for the use of a combination therapy for treating patients having a neoplasm, a proliferative disorder, pre-neoplasm or a precancerous lesion, comprising an inhibitor of the e1F4E gene product, a chemotherapeutic agent, and a therapeutically effective amount of a hedgehog pathway inhibitor, such as GDC-0449; and the method of using said combination therapy.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: January 17, 2017
    Assignee: Universite de Montreal
    Inventors: Katherine Borden, Hiba Zahreddine, Biljana Culjkovic Kraljacic
  • Combination Therapy Using Ribavirin As EIF4E Inhibitor
    Publication number: 20140343007
    Abstract: The present invention relates to pharmaceutical compositions and combination therapies for treating patents having a neoplasm or proliferative disorder, the combination comprises an inhibitor of the eIF4E gene product and a chemotherapeutic agent, wherein said combination therapy overcomes resistance developed in patients during anti-neoplastic treatment. The present invention also provides for the use of a combination therapy for treating patients having a neoplasm, a proliferative disorder, pre-neoplasm or a precancerous lesion, comprising an inhibitor of the eIF4E gene product, a chemotherapeutic agent, and a therapeutically effective amount of a hedgehog pathway inhibitor, and the method of using said combination therapy.
    Type: Application
    Filed: September 13, 2012
    Publication date: November 20, 2014
    Applicant: UNIVERSITE DE MONTREAL
    Inventors: Katherine Borden, Hiba Zahreddine, Biljana Culjkovic Kraljacic