Patents by Inventor Biljana Jovov

Biljana Jovov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8679766
    Abstract: The present invention provides methods of diagnosing and identifying subjects as having GERD comprising detecting E-cadherin fragments in a biological sample from the subject. The invention further provides methods for identifying subjects as having heartburn that is responsive to proton pump inhibitor therapy and subjects having an increased likelihood of a rapid relapse of GERD after reducing the dosage of PPIs or terminating PPI therapy. In addition, the present invention provides methods for monitoring the healing of erosive and nonerosive esophagitis of GERD without the need for esophagogastroduodenoscopy or esophagogastroduodenoscopy and biopsy, respectively.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: March 25, 2014
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Roy C. Orlando, Biljana Jovov, Nelia A. Tobey, Geraldine S. Orlando, Zorka Djukic
  • Publication number: 20120094318
    Abstract: The present invention provides methods of diagnosing and identifying subjects as having GERD comprising detecting E-cadherin fragments in a biological sample from the subject. The invention further provides methods for identifying subjects as having heartburn that is responsive to proton pump inhibitor therapy and subjects having an increased likelihood of a rapid relapse of GERD after reducing the dosage of PPIs or terminating PPI therapy. In addition, the present invention provides methods for monitoring the healing of erosive and nonerosive esophagitis of GERD without the need for esophagogastroduodenoscopy or esophagogastroduodenoscopy and biopsy, respectively.
    Type: Application
    Filed: November 29, 2011
    Publication date: April 19, 2012
    Inventors: Roy C. Orlando, Biljana Jovov, Nelia A. Tobey, Geraldine S. Orlando, Zorka Djukic