Abstract: Methods, systems, and computer programs are presented for splicing a client-server connection. One method includes an operation for splicing a client-server network connection by creating a first network connection between the client and a network device and a second network connection between the network device and the server. The method includes an operation for configuring in the network device a network processing unit (NPU) with a first and second offsets for the first and second network connections respectively. The incoming packets for the first and second network connections are then sent to the NPU for processing, which processes the packets in hardware to achieve low packet latency. The NPU adjusts the sequence number of the incoming packets of the first and second network connections based on the respective first and second offsets. The incoming packets are then sent to the destination after being processed.