Abstract: An automated chemical testing apparatus which includes a continuous flow front end portion and a discrete flow back end portion. Also provided is a collecting means for separately collecting these sample segments and the intersample segments, means for analyzing these sample segments, and a waste collection means for collecting waste fluids.

Abstract: A profile analysis reaction pack and related apparatus are disclosed, along with a method for simultaneously mixing, heating and reacting selected test reagents with multiple dilutions of a sample of body fluid to obtain a profile of the physiological condition of a given organ system. Each pack takes the form of a laminated card having a relatively rigid flat panel of transparent material secured to an opaque resilient panel, the resilient panel being preformed to define a plurality of generally semi-cylindrical reaction chambers disposed between the respective panels. During a profile test procedure, a sample of the body fluid to be tested is withdrawn from a storage chamber in the same pack and each reaction chamber is then injected with a diluted portion of the sample fluid. Temperature control is achieved by bracing the rigid panel of the pack against a fixed heated platen and by contacting the generally semi-cylindrical wall portion of each reaction chamber with a movable heated platen.

Abstract: A method and apparatus for determining coagulation times in such clinical laboratory procedures as prothrombin time tests, activated partial thromboplastin time tests, fibrinogen determinations, factor assays for specific blood coagulation factors, and the like. A fibrous filament is drawn at a predetermined rate through a small body of liquid to be tested and the interval, from the time a suitable coagulating agent is mixed with the liquid to the time the body of liquid clings to the filament and moves with it, is precisely measured as a direct indication of actual coagulation time. The liquid body is supported upon a non-wettable inclined surface bordered by walls defining a well for receiving the liquid and a pathway for its movement. Particularly effective results are achieved by utilizing a pair of spaced filaments moving at precisely the same rate, the filaments being bridged by a web or mass of clotted liquid when coagulation occurs.