Abstract: The present invention relates to a group of IMB-C5 series compounds having anti-coronavirus activity and the application thereof. The structure of the IMB-C5 series compounds is as shown in formula (1). The application is an application of the IMB-C5 series compounds in preparing a drug. The drug is a drug for inhibiting coronavirus, and is preferably a drug for treating human coronavirus infection. The coronavirus is preferably human ?-coronavirus or human ?-coronavirus, especially novel coronavirus (SARS-COV-2).

Abstract: The present disclosure provides a preparation method of an easy-to-cook whole grain based on microwave-induced cracking, and belongs to the technical field of food processing. In the present disclosure, the preparation method of an easy-to-cook whole grain includes the following steps: subjecting a whole grain to a heat-moisture treatment, and conducting short-time microwave-induced cracking, tempering, and cooling to obtain the easy-to-cook whole grain. The easy-to-cook whole grain obtained by the preparation method of the present disclosure has a complete grain, a slightly-expanded volume, and fine cracks on its surface. Compared with unprocessed whole grains, the easy-to-cook whole grain has a water absorption increased from 1.35 times to 1.9 times an original weight of the unprocessed whole grains during rice steaming.

Abstract: This disclosure related to a group of peptide derivative Omicsynins with antiviral activity against influenza virus and coronavirus. It also related uses of these derivatives, the chemical formula of the peptide derivative Omicsynins is shown in formula (1): R1—R4 are shown in the following table. NO. substituent1 substituent2 substituent3 R1 Basic amino-acid side chains including lysine, histidine, citrulline residues, and etc. R2 —CH(CH3)2, —CH(CH3)CH2CH3 —CH2CH(CH3)2 Neutral amino-acid side chain including tryptophan, serine, threonine, cysteine residues and etc. R3 R3 including tyrosine, lysine, histidine, citrulline residues, and etc. R4 —CH2OH —CHO R4 including —CH2NH2, —CH?NH,— CH?NOH, —COOH, —COOR5 (R5 represents alkyl groups containing 1-3 carbons), -CONH2 and etc.

Abstract: A real time and quantitative method of measuring traction force of living cells include the following procedures. Place AT-cut and BT-cut quartz crystals of the same frequency, surface morphology and/or modified with the same cell adhesion molecules in petri dishes or detection cells; add the cells to the petri dishes or detection cells, the cell traction force at arbitrary time t during adhesion of the cells or under different internal/external environmental stimulations is estimated by the following equation: ?St=(KAT?KBT)?1[tqAT?ftAT/frAT?tqBT?ftBT/frBT]. The method can be used to track the dynamic changes of cells generated force during the adhesion of cells and under different internal/external environmental stimulations, such as the effects of drugs. The drugs can be added before or after the adhesion of the cells. This method is suitable for all adherent cells, including primary cells and passage cells.

Abstract: An automatic spin coating system includes a dispensing assembly and a base assembly. The dispensing assembly comprises a dispensing device that contains a coating material, a pulley assembly, a drive gear, and a smooth wheel. The base assembly includes a coating plate for receiving the coating material, a chuck plate for securing the coating plate, a stepper pin capable of engaging the drive gear of the dispensing assembly, and an electric motor for spinning the chuck plate. The dispensing device further comprises a vessel assembly to provide immobilization of the dispensing device, and a tubing assembly to control the flow of the coating material. The dispensing device is connected to the pulley assembly, which in turn is connected to the drive gear and the smooth wheel.

Abstract: A real time and quantitative method of measuring traction force of living cells include the following procedures. Place AT-cut and BT-cut quartz crystals of the same frequency, surface morphology and/or modified with the same cell adhesion molecules in petri dishes or detection cells; add the cells to the petri dishes or detection cells, the cell traction force at arbitrary time t during adhesion of the cells or under different internal/external environmental stimulations is estimated by the following equation: ?St=(KAT?KBT)?1[tqAT?ftAT/frAT?tqBT?ftBT/frBT]. The method can be used to track the dynamic changes of cells generated force during the adhesion of cells and under different internal/external environmental stimulations, such as the effects of drugs. The drugs can be added before or after the adhesion of the cells. This method is suitable for all adherent cells, including primary cells and passage cells.

Abstract: An automatic spin coating system includes a dispensing assembly and a base assembly. The dispensing assembly comprises a dispensing device that contains a coating material, a pulley assembly, a drive gear, and a smooth wheel. The base assembly includes a coating plate for receiving the coating material, a chuck plate for securing the coating plate, a stepper pin capable of engaging the drive gear of the dispensing assembly, and an electric motor for spinning the chuck plate. The dispensing device further comprises a vessel assembly to provide immobilization of the dispensing device, and a tubing assembly to control the flow of the coating material. The dispensing device is connected to the pulley assembly, which in turn is connected to the drive gear and the smooth wheel.

Abstract: An implantable electronic tag (100) for a tire and an assembly process. The electronic tag (100) mainly comprises: an antenna (102); a radio frequency chip module (101); and a connection terminal (103). The radio frequency chip module (101) has an electrode (101b) provided thereon. The connection terminal (103) has one end connected to the antenna (102) and another end in cold-press connection with the electrode (101b) of the radio frequency chip module (101). Upon assembly, a radio frequency chip is encapsulated to form the radio frequency chip module (101). The connection terminal (103) is initially riveted to the antenna (102) and then connected to the electrode (101b) of the encapsulated body by means of cold-pressing. The radio frequency chip module (101) connected to the antenna (102) is encapsulated. The implantable electronic tag (100) for a tire is an ultra-high frequency, readable and writable radio frequency tag.

Abstract: A drill bit includes a tool body having a main body in the form of a cylinder. A chip removing structure is provided on the main body. The tool body has a distal end provided with a clamping slot and a cutter inlaid in the clamping slot. The cutter has at least two blade portions arranged circumferentially on the distal end of the tool body and extending radially relative to the tool body. Each of the blade portions has a front side along the drill bit's rotating direction and a back side against the rotating direction. The clamping slot covers the back side of one blade portion by an area larger than that used to cover the front side of the same blade portion.

Abstract: A drill bit includes a tool body having a main body in the form of a cylinder. A chip removing structure is provided on the main body. The tool body has a distal end provided with a clamping slot and a cutter inlaid in the clamping slot. The cutter has at least two blade portions arranged circumferentially on the distal end of the tool body and extending radially relative to the tool body. Each of the blade portions has a front side along the drill bit's rotating direction and a back side against the rotating direction. The clamping slot covers the back side of one blade portion by an area larger than that used to cover the front side of the same blade portion.

Abstract: The present invention relates to use of a microRNA or an inhibitor thereof, and specifically, the present invention relates to use of a microRNA or an inhibitor thereof in preparing a medicament for regulating lipid metabolism or preparing a medicament for preventing or treating a disease related to lipid metabolism. The microRNA is one or more of the following: miRNA-96, miRNA-185, and miRNA-223. The present invention also relates to use of the microRNA or the inhibitor thereof in regulating the expression level of a protein related to lipid metabolism. The present invention also relates to a composition comprising the microRNA or the inhibitor thereof. The microRNA or the inhibitor thereof in the present invention can be used as a pharmaceutical component, and can be applied in preventing or treating a disease caused by lipid metabolism disorders such as hyperlipidemia, atherosclerosis, coronary heart disease or other diseases.

Abstract: The present invention relates to use of a microRNA or an inhibitor thereof, and specifically, the present invention relates to use of a microRNA or an inhibitor thereof in preparing a medicament for regulating lipid metabolism or preparing a medicament for preventing or treating a disease related to lipid metabolism. The microRNA is one or more of the following: miRNA-96, miRNA-185, and miRNA-223. The present invention also relates to use of the microRNA or the inhibitor thereof in regulating the expression level of a protein related to lipid metabolism. The present invention also relates to a composition comprising the microRNA or the inhibitor thereof. The microRNA or the inhibitor thereof in the present invention can be used as a pharmaceutical component, and can be applied in preventing or treating a disease caused by lipid metabolism disorders such as hyperlipidemia, atherosclerosis, coronary heart disease or other diseases.

Abstract: This disclosure describes a portable device that conveniently applies cancer patient blood sample into a test strip to determine the level of the patient's metastatic circulating tumor cells. Proper use of this device provides end users with the diagnostic and prognostic information of the cancer patient, and any effect of applied therapies. The device can also be used to screen effective drugs for any known metastatic phenotype disruption.

Abstract: In general, the invention is directed to techniques for breaking out mobile data traffic from a mobile service provider network to a packet data network. For example, as described herein, a breakout gateway device (BGW) receives a first service request and data traffic for a data session associated with the requested service from a mobile device in a radio access network, wherein the first service request is addressed to a serving node of a mobile core network of the mobile service provider network, and wherein the data traffic is destined for the PDN. A control packet analysis module forwards the first service request from the breakout gateway device to the serving node. A breakout module of the BGW bypasses the serving node by sending the data traffic from the breakout gateway device to the PDN on a data path from the radio access network to the PDN.

Abstract: A network system includes a provider backbone bridged network (PBBN) and a multi-homed provider bridge network (PBN) having a plurality of L2 switches that operate as backboned edge bridges (BEBs) to bridges L2 packets between the PBN and the PBBN. A first one of the L2 switches is configured to bridge L2 packets from a first backbone VLAN (B-VLAN) to the PBN when a physical link of the multi-homed PBN is operational. The L2 switch is further configured to shunt the L2 packets from the first backbone VLAN to a second one of the L2 switches operating as a secondary BEB of the multi-homed PBN via a second B-VLAN when the physical link is non-operational.

Abstract: The invention is a nano-entity conjugate for use in an in vivo immunomagnetic hyperthermia system for the detection and treatment of any cell or virus having a target surface receptor which encompasses a technology platform that can be used for both real-time monitoring of any cell or virus having a target surface receptor and as a delivery platform for certain types of treatment that are conducive for in vivo applications. The system allows of cell or virus enumeration; cell or virus capture; and cell or virus removal from the patient's circulatory system in-vivo using immunomagnetic hyperthermia. The application of immunomagnetic hyperthermia may actually diminish and eventually stop the progression of cancer and other blood borne or blood affected diseases.

Abstract: In general, the invention is directed to techniques for breaking out mobile data traffic from a mobile service provider network to a packet data network. For example, as described herein, a breakout gateway device (BGW) receives a first service request and data traffic for a data session associated with the requested service from a mobile device in a radio access network, wherein the first service request is addressed to a serving node of a mobile core network of the mobile service provider network, and wherein the data traffic is destined for the PDN. A control packet analysis module forwards the first service request from the breakout gateway device to the serving node. A breakout module of the BGW bypasses the serving node by sending the data traffic from the breakout gateway device to the PDN on a data path from the radio access network to the PDN.

Abstract: This disclosure describes a portable device that conveniently applies cancer patient blood sample into a test strip to determine the level of the patient's metastatic circulating tumor cells. Proper use of this device provides end users with the diagnostic and prognostic information of the cancer patient, and any effect of applied therapies. The device can also be used to screen effective drugs for any known metastatic phenotype disruption.

Abstract: A method for protecting WDM transmission. On the first transmission direction, the first node implements service transmission to the second node by selecting one from the two transmission paths protected by each other, the second node implements two-path reception based on the two transmission paths; on the second transmission direction contrary to the first transmission direction, the second node implements two-path service sending via the two transmission paths protected by each other, the first node implements reception by selecting one from the two transmission paths. A system for implementing the WDM transmission protection and an apparatus thereof.

Abstract: A multifunction image display device that consists of an image display device (such as televisions, computer monitors, billboards etc.) and an integrated retractable static visual display utilizes the display panel area to present static visual image such as decorative art works, and can fully address the dull idle screen problem by utilizing the frame of the image display device and an integrated retractable and replaceable visual display to serve as a conventional picture-frame while the image display device is not in use, and to serve as a image screen while the image display device is in use. The static visual display is made of a sheet material having decorative art woks.