Abstract: The present invention relates to a pharmaceutical composition comprising trimebutine as an active ingredient for prevention or treatment of cancer. Having an excellent effect of selectively inhibiting growth and proliferation of cancer stem cells, the pharmaceutical composition can suppress the recurrence, metastasis, and progression of cancer even when used alone. Thus, the composition can be advantageously used as a pharmaceutical composition for prevention or treatment of cancer or in combination with other agents.

Abstract: According to a quantization interconnect apparatus and an operating method thereof according to the exemplary embodiment of the present disclosure, in a quantization artificial neural network accelerator system, the quantization is performed in the interconnect bus according to a precision without separate processing of the CPU/GPU so that as compared with the quantization by a host processor and an accelerator according to a quantization method of the related art, a number of instructions is reduced to improve the performance/memory efficiency. Further, a computational burden of the host process is reduced to reduce the power and improve the performance.

Abstract: A system and method for preventing hacking of blockchain is proposed.

Abstract: The present invention relates to: a substituted thiazolidinedione derivative compound having a novel structure acting as a sterol regulatory element-binding protein-1 (SREBP1) inhibitor, a hydrate thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating cancer, comprising same as an active ingredient.

Abstract: A map generation model building device includes a memory storing a map generation model building program, and a processor configured to execute the program, wherein the program generates embedding data by applying captured images taken by a movement device to an encoder module, generates spatial map data by recording the embedding data in map base data based on location information of the movement device, generates a rendering image based on the location information of the movement device in the spatial map data by using a decoder module, and train the a map generation model by comparing the rendering image with the captured image through a loss function and by updating the encoder module and the decoder module, the map base data includes a plurality of grids in which the embedding data is recorded, the embedding data includes RGB information and depth information for each pixel of the captured image.

Abstract: A pouch-type secondary battery includes a sealing part wherein a two-layer pouch-type battery case is heat-sealed in a state of accommodating an electrode assembly, and includes a cover member positioned between a thickness side of an electrode assembly and a pouch-type battery case on at least one of the four thickness sides constituting the thickness of an electrode assembly. The cover member disconnects a separator from an inner coating layer of the pouch and prevents the separator from being adhered to the inner coating layer when forming the sealing part, and thus prevents damage to the inner coating layer due to the movement of the electrode assembly.

Abstract: The present invention relates to a microorganism culture production amount prediction system and method with improved accuracy in predicting the microorganism culture production amount using a metabolic model equation by calculating the predicted substrate concentration from the metabolic model equation, calculating the actually measure substrate concentration from the spectrum data of the culture solution, comparing the predicted substrate concentration with the actually measured substrate concentration, and updating the parameters of the metabolic model equation, in a method for predicting the culture concentration of microorganisms with known metabolic model equation governing the metabolic model.

Abstract: An acoustic output of therapeutic devices used in shock wave therapy can be obtained by measuring the pressure waves radiated from the pressure wave transducer in water. Since the pressure waves used in shock wave therapy generate severe bubbles in water, measuring the surface vibrations of the pressure wave transducer using the laser Doppler method includes significant noise caused by the bubbles. This invention utilizes a filter generated to eliminate the noise in the vibration signals measured by the laser Doppler method, which is caused by the bubbles. The filter is generated by comparing the vibration signals measured in degassed distilled water with the reference signals measured in air at the minimum output setting of the shock wave generation device. Using the filter, it is possible to estimate the vibration signals of the pressure wave transducer generated underwater under the set conditions of the specific shock wave generating device.

Abstract: According to various exemplary embodiments, A training operation variation compensating apparatus and method of a computation-in-memory based artificial neural network using a non-volatile memory array and a robust memory array which perform an operation for training an artificial neural network using a predetermined initial weight and weight noise supplying unit which performs the training operation using a weight obtained by reflecting a noise to an initial weight by applying a noise to any one of the non-volatile memory array and the robust memory array are applied to overcome a limitation of the fundamental memory device variation in the existing processing-in-memory based artificial neural network training to perform a high performance training and correct an accuracy without intervention of the host processor, thereby increasing the energy efficiency.

Abstract: The present invention relates to a lead transport gripper that is capable of stably transporting an electrode lead, without twisting the electrode leads due to friction or pressure.

Abstract: According to a quantization interconnect apparatus and an operating method thereof according to the exemplary embodiment of the present disclosure, in a quantization artificial neural network accelerator system, the quantization is performed in the interconnect bus according to a precision without separate processing of the CPU/GPU so that as compared with the quantization by a host processor and an accelerator according to a quantization method of the related art, a number of instructions is reduced to improve the performance/memory efficiency. Further, a computational burden of the host process is reduced to reduce the power and improve the performance.

Abstract: The electrode assembly of the present invention includes a protective block consisting of a first protective panel and a second protective panel extending vertically from one longitudinal side of the first protective panel at a) an edge portion in a full length direction of the electrode laminate, b) an edge portion in a full width direction, or c) at each of edge portions in the full length direction and the full width direction, thereby preventing a phenomenon in which the separator is folded.

Abstract: The present disclosure provides a method of sealing a pouch-type battery case including first and second case units. An electrode assembly accommodated in the first and second case units. The method including a bending operation, a first sealing operation, and a second sealing operation. Each of the first and second case units including an accommodation portion and an extension at least partially surrounding the accommodation portion. The electrode assembly being disposed between the accommodation portions of the first and second case units. First regions or second regions of the extensions of the first and second case units adjacent to an end portion of one side or the other are bonded. In the second sealing operation, seventh or eighth regions of the extensions of the first and second case units positioned at the one side or the other side of the electrode assembly facing each other are bonded.

Abstract: The present invention relates to a 5-membered heteroaryl derivative containing an N, and a pharmaceutical composition for use in preventing or treating mental disorders, containing same as an active ingredient, wherein the derivative is excellent in the triple reuptake inhibitory effect of serotonin, norepinephrine, and dopamine, and thus can be useful in the treatment of mental disorders.

Abstract: A system and method for preventing hacking of blockchain is proposed.

Abstract: The present invention relates to a pharmaceutical composition comprising trimebutine as an active ingredient for prevention or treatment of cancer. Having an excellent effect of selectively inhibiting growth and proliferation of cancer stem cells, the pharmaceutical composition can suppress the recurrence, metastasis, and progression of cancer even when used alone. Thus, the composition can be advantageously used as a pharmaceutical composition for prevention or treatment of cancer or in combination with other agents.

Abstract: Provided is a prebiotic composition containing butyryl-fructooligosaccharide (B-FOS). B-FOS of the present invention facilitates selective growth of probiotics, thereby controlling intestinal microbes and contributing to physiological functions as an energy source of intestinal epithelial cells.

Abstract: A method for inducing an activity of a user's autonomic nervous system is provided. The method includes steps of: (a) on condition that each of the user's reference heart rate information corresponding to each of active states of the user's autonomic nervous system is obtained, an inducing device, if a specific active state of the autonomic nervous system is selected by the user, acquiring first reference heart rate information of the user corresponding to the specific active state of the autonomic nervous system; and (b) the inducing device supporting a first vibration stimulus with a first period corresponding to the first reference heart rate information to be applied to the user, to thereby allow the user's real-time average cardiac interval to be synchronized with the first vibration stimulus.

Abstract: Disclosed is a method for providing an in-game messenger service comprising: storing a game program in a platform server; associating an in-game messenger program for the game program; and transmitting the in-game messenger program associated with the game program to a user terminal as the game program is transmitted from the platform server to the user terminal.

Abstract: Provided are a posttraumatic stress disorder (PTSD) animal model in which dopamine receptor subtype 4 (D4R) is damaged or deficient, a method for preparing the same, a method for screening a drug for treating PTSD using the same, and a pharmaceutical composition for treating PTSD comprising a drug detected by the screening method. As it is identified that a specific type of dopamine receptor is associated with a mechanism for fear memory expression induced by long-term depression (LTD), the understanding of pathogenesis of PTSD may be heightened, the animal model exhibiting similar clinical conditions of PTSD and the method for preparing the same may be applied in analyses for stability and effectiveness of a therapeutic agent for PTSD and screening of a therapeutic drug. Further, an agonist of D4R contained in the composition has been approved by the US FDA and clinically used for psychiatric diseases such as schizophrenia, and thus may be immediately used for clinical applications for PTSD symptoms.