Abstract: A method and an Internet of Things system for smart gas adaptive pressure regulation based on a calorific value of gas are provided. The method comprises: acquiring calorific value of gas data, wherein the calorific value of gas data is acquired on the basis of a pressure regulation station; acquiring a first pressure regulation parameter of the pressure regulation station, wherein the first pressure regulation parameter is used for reflecting current pressure regulation data of the pressure regulation station; determining whether the calorific value of gas data meets a first preset condition; in response to the calorific value of gas data not meeting the first preset condition, adjusting the first pressure regulation parameter; and determining a second voltage regulation parameter of the pressure regulation station on the basis of the adjusted first voltage regulation parameter, wherein the second voltage regulation parameter is updated pressure regulation data.

Abstract: A printer control method, a printer, and a computer-readable storage medium are provided. The method includes: controlling a print head assembly of a printer to print a target outer wall set of a three-dimensional model; and controlling the print head assembly to print a target infill set corresponding to the target outer wall set, with the number of layers contained in the target infill set being less than that contained in the target outer wall set, thereby enhancing surface quality of the three-dimensional model while reducing printing time.

Abstract: Provided is a linker-containing antibody drug conjugate. Also involved are a pharmaceutical composition comprising the antibody conjugate, a use of a linker, and a use of the antibody conjugate in the preparation for a drug for preventing and/or treating diseases.

Abstract: An advanced detection apparatus for a tunnel boring machine based on seismic waves from a controllable seismic source, the advanced detection apparatus may include: electromagnetic controllable seismic source assemblies arranged on both sides of a working platform of the tunnel boring machine and including a telescopic push rod, a counterweight housing, an airbag, a support, a first base, and a second base, wherein the telescopic push rod is fixed on a side of the counterweight housing facing the rock wall; and both the counterweight housing and the airbag are fixed to the first base, the airbag is located on a side of the counterweight housing distal from the telescopic push rod, and the first base is fixedly connected to the second base via the support.

Abstract: An advanced detection method for a tunnel boring machine (TBM).

Abstract: A camera module and an electronic device are provided. The camera module includes a voice coil motor, a lens, a module circuit board, and an image sensor, where the voice coil motor includes a base, a driving mechanism, and a housing, the lens is mounted in the driving mechanism which is connected to the base, both the base and the image sensor are disposed on the module circuit board, the image sensor is located on a light exit side of the lens, and the housing is fastened to the base and covers at least a part of the driving mechanism; the base includes a plastic piece and a metal piece, and the metal piece is fastened to the plastic piece; and the housing includes a metal portion fastened to the metal piece, and the metal piece is electrically connected to a ground pin of the module circuit board.

Abstract: A method for arranging a water detection structure based on borehole-tunnel induced polarization. The arranging method may comprise: arranging a plurality of forward boreholes at intervals on the outer edge area of the tunnel face; arranging borehole detection cables in each forward borehole, wherein each borehole detection cable comprises a plurality of detection electrodes, and each detection electrode in a borehole detection cable is respectively configured as a power supply electrode A, a power supply electrode B; arranging a plurality of the out-of-borehole detection electrodes in an array on the tunnel face outside an area occupied by the plurality of forward boreholes, wherein each out-of-borehole detection electrode is configured as a measuring electrode M, a measuring electrode N; the power supply electrodes form a closed power supply circuit, while the measuring electrodes form a closed measuring circuit.

Abstract: An integrated die ejector for separating a die from a wafer, the die ejector includes an ejector mechanism that includes an ejector pin. There is an ejector base coupled to the ejector pin and configured to couple the integrated die ejector to a die attach ejector machine. There is a pepper pot at least partially surrounding the ejector mechanism and ejector base and a sleeve coupled thereto and positioned between the ejector mechanism and pepper pot. The sleeve and pepper pot define an upper and lower motion limit of the ejector base and retain the ejector mechanism within the pepper pot such that the integrated die ejector may be coupled to and decoupled from the die attach ejector machine as a single unit to reduce installation time.

Abstract: According to a turbine hydroelectric power generation device and a power generation method based on pressurized water inlet pipelines, after water flows are input into liquid inlet flow channels and guided by guide vanes, by arranging the liquid inlet flow channels that are the vortex-shaped spiral flow channels, it can be ensured that the water flows are evenly diverted by the guide vanes and thus are output to a driving rotor at the same flow velocity to impact and drive the driving rotor to rotate. The driving rotor can drive, during rotation, a power generation rotor to rotate inside a magnetic power generation mechanism to generate electricity, and the input water flows are finally collected by a bottom liquid discharge mechanism and then separated into multiple water flows to be output respectively.

Abstract: A lens driving apparatus includes a base, a moving base, a lens carrier, a variable aperture, and a focus driving device. The moving base is disposed on the base; the lens carrier is disposed on the moving base; the variable aperture is disposed on a side, of the lens carrier, away from the base; the focus driving device is configured to drive the lens carrier to move relative to the moving base in an axial direction of the variable aperture. The base has a plurality of corner portions in a circumferential direction, at least two of the corner portions are provided with first pins, and the first pins are electrically connected to the variable aperture and the focus driving device through a connection line.

Abstract: A magnetic attraction component is provided. The magnetic attraction component includes a magnet unit. The magnet unit includes a plurality of magnets. Two adjacent magnets, in the plurality of magnets, that repulse each other are welded. This application may be applied to an electronic device such as a mobile phone.

Abstract: A composition of lactoferrin, osteopontin and calcium in defined proportions, which can alleviate and inhibit the expression of pro-inflammatory factors at the mRNA level in RAW264.7 macrophages induced by LPS, and down-regulate the expression of inflammatory pathway-associated proteins at the protein level, thereby alleviating the effects of inflammatory responses. Use of the composition in the preparation of a product for resisting enteritis and/or protecting the integrity of the intestinal barrier.

Abstract: The present disclosure presents a device and method for monitoring and early warning of information perception regarding urban yellow mud water, featuring a rainfall collecting component, a video shooting component, a sediment content monitoring component, a water level monitoring component and a main controller. The video shooting component evaluates the long-term trend of yellow mud water production in a monitoring area by analyzing the color depth of captured water flow, sediment content in the pipeline's flow section, and meteorological rainfall data from the rainfall collecting component. Utilizing data on color, sediment content, flow section, and rainfall, this system achieves unsupervised real-time monitoring and precise early warning for yellow mud water. It provides a scientific basic for traceability, dynamic monitoring, and address challenges such as low measurement accuracy and omitted applicability found in existing methods.

Abstract: The present invention relates to the field of genomic engineering. In particular, a chimeric prime editing (cPE) system is disclosed comprising elements including, but not limited to a Cas9 nickase (nCas9)/high fidelity nucleotide polymerase (HFNTPol) RNA, one or more single guide RNAs (sgRNAs), and a chimeric prime editor template oligonucleotide (cpetODN) comprising a deoxyribonucleic acid nucleotide polymerase template (NPT) and a primer binding site. For example, the sgRNA and the cpetODN are ligated into a single oligonucleotide. Alternatively, the sgRNA and the cpetODN are free and independent molecules (e.g., modular). This cPE system results in precise and efficient genome editing in cells and in adult mouse liver which is advantageous over conventional sgRNA prime editor fusion constructs. This flexible and modular system is an improvement in the art to obtain precise genome editing.

Abstract: Disclosed is a compound of a general formula (I), which may be used for the treatment of ATR kinase-mediated diseases, for example, proliferative diseases such as cancer. Further disclosed are a preparation method for the compound of the general formula (I), a pharmaceutical composition, and use of the pharmaceutical composition for the treatment of ATR kinase-mediated diseases.

Abstract: Disclosed are a ceramic material and a preparation method and use thereof, belonging to the technical field of ceramic materials. The ceramic material includes a titanium alloy with a porous lattice structure, a ceramic, and an aluminum alloy; where the porous lattice structure is provided with voids; the ceramic is embedded in the voids; and the aluminum alloy fills in the porous lattice structure.

Abstract: Provided is an anti-PD-L1 antigen binding protein, capable of binding to primate-derived PD-L1 with a KD value of 1×10?8 M or less. The antigen binding protein can block the binding of PD-1 and CD80 to PD-L1, stimulate the secretion of cytokines in immune cells, and can inhibit tumor growth and/or tumor cell proliferation. Also provided is a fusion protein, comprising human TGFBRII or a fragment thereof and the antigen binding protein. Also provided is an application of the antigen binding protein and/or the fusion protein in the prevention and treatment of tumors or cancers.

Abstract: Some embodiments of the present disclosure provide a method, an Internet of Things system, and a storage medium for determining a street cleaning route in a smart city. The method may include obtaining street monitoring information of a target area; determining distribution of fallen leaves on the street; determining cleaning difficulty of each street in the target area; determining, based on the total amount of fallen leaves and the cleaning difficulty, at least one street to be cleaned from the target area; determining the continuous action sequence including cleaning actions for each of the streets to be cleaned; for any continuous action sequence of the at least one continuous action sequence, determining a reward value of each cleaning action of the continuous action sequence, and determining the return value of each continuous action sequence; and determining the fallen leaf cleaning route of the target area.

Abstract: Disclosed are a display substrate, a preparation method therefor and a display apparatus. The display substrate includes a shielding conductive layer and a functional structure layer, wherein the shielding conductive layer at least includes a first connection line, and the functional structure layer at least includes a data signal line and a second connection line; in a plane parallel to the display substrate, the display substrate includes a plurality of circuit units forming a plurality of unit rows and a plurality of unit columns, at least one circuit unit includes a pixel driving circuit, the data signal line is connected to a plurality of pixel driving circuits of one unit column, the data signal line is configured to provide a data signal to the pixel driving circuit; the second connection line is connected with the first connection line, and the data signal line is connected with the second connection line.

Abstract: Provided is a high pressure water jet cutting apparatus for a rock-wall crane girder in an underground cavern powerhouse, comprising: a guiding mechanism, a support mechanism, and a jet cutting mechanism, where the guiding mechanism is detachably connected to a steel tube frame, the steel tube frame is erected according to drilling positions, and the support mechanism is connected to the guiding mechanism and is capable of moving on the guiding mechanism; and the support mechanism is connected to the jet cutting mechanism, the support mechanism is configured to adjust an angle of a hollow jet pipeline protection tube of the jet cutting mechanism, a tail end of the hollow jet pipeline protection tube is connected with a nozzle, and the steel tube frame is connected to a positioning steel tube through which the hollow jet pipeline protection tube passes.