Abstract: The present invention relates to a pharmaceutical composition containing an avocado oil fraction as an active ingredient for prevention or treatment of hearing loss. Specifically, the avocado oil fraction according to the present invention, especially, an isopropanol fraction of avocado oil significantly increases the number of hair cells reduced by neomycin in zebrafish models, so the isopropanol fraction of avocado oil can be favorably used in the treatment of hearing loss.

Abstract: The present invention relates to a pharmaceutical composition containing an avocado oil fraction as an active ingredient for prevention or treatment of hearing loss. Specifically, the avocado oil fraction according to the present invention, especially, an isopropanol fraction of avocado oil significantly increases the number of hair cells reduced by neomycin in zebrafish models, so the isopropanol fraction of avocado oil can be favorably used in the treatment of hearing loss.

Abstract: A composition including Cuscuta japonica Choisy extract, or the extract of Rehmannia glutinosa Libschitz var. purpurea MAKINO and Cuscuta japonica Choisy is provided. The composition, which can be a pharmaceutical or food composition, is useful for preventing, ameliorating, or treating hearing loss. A method for ameliorating, preventing, or treating hearing loss, in particular, acoustic trauma, temporary or permanent hearing loss by effectively inhibiting the threshold shift induced by noise and the likes is disclosed.

Abstract: A composition including Cuscuta japonica Choisy extract, or the extract of Rehmannia glutinosa Libschitz var. purpurea MAKINO and Cuscuta japonica Choisy is provided. The composition, which can be a pharmaceutical or food composition, is useful for for preventing, ameliorating, or treating hearing loss. A method for ameliorating, preventing, or treating hearing loss, in particular, acoustic trauma, temporary or permanent hearing loss by effectively inhibiting the threshold shift induced by noise and the likes is disclosed.

Abstract: The present invention provides a pharmaceutical composition for treating or preventing tinnitus, comprising the extract of Cuscuta japonica Choisy and Rehmannia glutinosa Libschitz var. purpurea MAKINO. In addition, the present invention provides a functional food for ameliorating or preventing tinnitus, comprising the extract of Cuscuta japonica Choisy and Rehmannia glutinosa Libschitz var. purpurea MAKINO.

Abstract: Disclosed is a pharmaceutical composition for preventing or treating hearing loss, comprising Cuscuta japonica Choisy extract, or the extract of Rehmannia glutinosa Libschitz var. purpurea MAKINO and Cuscuta japonica Choisy. In addition, the present invention provides a food composition for preventing or ameliorating hearing loss, comprising Cuscuta japonica Choisy extract, or the extract of Rehmannia glutinosa Libschitz var. purpurea MAKINO and Cuscuta japonica Choisy. The composition inhibits hearing loss, in particular, acoustic trauma, temporary or permanent hearing loss by effectively inhibiting the threshold shift induced by noise and the likes, and thusit is effective in preventing or treating hearing loss. In addition, it can be administered orally, thereby drug compliance of patients can be enhanced.