Abstract: This invention describes a magnetoresistive inertial sensor chip, comprising a substrate, a vibrating diaphragm, a magnetic field sensing magnetoresistor and at least one permanent magnet thin film. The vibrating diaphragm is located on one side surface of the substrate. The magnetic field sensing magnetoresistor and the permanent magnet thin film are set on the surface of the vibrating diaphragm displaced from the base of the substrate. A contact electrode is also arranged on the surface of the vibrating diaphragm away from the base of the substrate. The magnetic field sensing magnetoresistor is connected to the contact electrode through a lead. The substrate comprises a cavity formed through etching and either one or both of the magnetic field sensing magnetoresistors and the permanent magnet thin film are arranged in a vertical projection area of the cavity in the vibrating diaphragm portion.

Abstract: Disclosed are compounds of Formula I, methods of using the compounds for inhibiting KRAS activity and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders associated with KRAS activity such as cancer.

Abstract: A well cementing method is described for improving cementing quality by controlling the hydration heat of cement slurry. By controlling the degree and/or rate of hydration heat release from cement slurry, the method improves the hydration heat release during formation of cement with curing of cement slurry, improves the binding quality between the cement and the interfaces, and in turn improves the cementing quality at the open hole section and/or the overlap section. The cementing method improves cementing quality of oil and gas wells and reduces the risk of annular pressure.

Abstract: A new sliding sleeve relates to the technical field of oil and gas well completion and reservoir stimulation, comprising an upper connector, a lower connector, an outer housing, an inner sleeve and a shear pin. The upper connector and the lower connector are respectively connected to two ends of the outer housing, and the inner sleeve is locked in the outer housing via the shear pin, wherein a flow guiding hole is provided in the outer housing, and the inner sleeve can open or close the flow guiding hole, wherein at least two grooves for engaging with at least two corresponding tooth-shaped elements on a sliding sleeve opening tool are disposed along an axial direction in the inner sleeve, and wherein an erosion-resistant ring is embedded in the groove, and an inner diameter of the erosion-resistant ring is larger than or equal to an inner diameter of the inner sleeve.

Abstract: An imaging module includes an electric cable including a plurality of wirings, an imager having an imaging surface intersecting an axial direction of a distal end of the electric cable, and a flexible wiring board configured to electrically connect the imager and the electric cable. The wiring board includes a plurality of extending portions that extend from at least three portions of a connection portion connected with the imager. At least one wiring pad to which at least one of the plurality of wirings of the electric cable is connected is provided in each of the plurality of extending portions.

Abstract: The invention relates to a GDSL lipase, genetically-engineered bacteria and an application thereof. The GDSL lipase is derived from Streptomyces diastaticus CS1801 and its amino acid sequence is as shown in SEQ ID NO.2. After construction of a genetically-engineered bacterium strain, a GDSL lipase is generated through fermentation. Through this enzyme, vitamin A and palmitic acid are converted to produce vitamin A palmitate. The content of the vitamin A palmitate obtained from the conversion is 16.35 mg/L at most. The conversion efficiency is 81.75% at most. This lipase provides a new path to synthesize vitamin A palmitate by the enzymatic method and has an important application prospect.

Abstract: A hydrostatic transmission mechanism of the power split transmission system is in driving connection to the sun gear of the first planetary gear train and the sun gear of the second planetary gear train. The planetary carrier of the first planetary gear train is connected to the planetary carrier of the second planetary gear train. The planetary carrier of the first planetary gear train is connected to the sun gear of a third planetary gear train. The driving plate of a third clutch is in transmission connection to the gear ring of the third planetary gear train. The driving plate of a fourth clutch is in transmission connection to the sun gear of the third planetary gear train. Each of the driven plate of the third clutch and the driven plate of the fourth clutch is connected to an output main shaft.

Abstract: Disclosed in the present invention are a capillary channel environmental sensor and a preparation method therefor. The capillary channel environmental sensor comprises a transfer cavity and at least one capillary channel. The cross sectional area of the transfer cavity is greater than the cross sectional area of the capillary channel, and one end of the capillary channel is connected with the transfer cavity; an elastic transfer diaphragm is provided between the transfer cavity and an external measurement environment. A positioned droplet is provided in the interior of the capillary channel, the positioned droplet is in tight contact with the inner walls of the capillary channel and the positioned droplet is in tight contact with a transfer medium.

Abstract: The disclosed invention is a MEMS environmental sensor and preparation method thereof. A transfer cavity is produced in the middle of a transfer substrate of a MEMS environmental sensor, and a transfer medium is located inside the transfer cavity. The surface area of an input port is larger than the surface area of an output port. An elastic transfer membrane is provided on the surface of the input port, and an elastic pressure membrane is provided on the surface of the output port. A load bearing cavity is provided in a load bearing substrate, a magnetic sensing element is positioned inside the load bearing cavity, and the load bearing cavity partially overlaps with the output port. The surface area of the input port of the transfer cavity is larger than the surface area of the output port, and on the basis of Pascal's principle, differences in the volume of the transmission cavity are used to transform a small displacement in a region of large volume into a large displacement in a region of small volume.

Abstract: A magnetoresistive acoustic wave sensor with high sensitivity and an array device thereof is disclosed, in which a magnetoresistive acoustic wave sensor comprises a protective tube shell, a magnetic vibration assembly, and a magnetoresistive chip located inside the protective tube shell. The protective tube shell comprises at least one opening which is covered by the magnetic vibration assembly. The plane where the magnetoresistive sensor chip is located is perpendicular to the plane where the magnetic vibration assembly is located, and the sensing direction of the magnetoresistive sensor chip is located in the plane where magnetoresistive sensor chip is located, and is perpendicular to or parallel to the plane where the magnetic vibration assembly is located.

Abstract: The present invention relates to a lipase-producing strain and application thereof. The strain is classified and named Bacillus subtilis CS1802, with a preservation number of CCTCC NO: M2018262. The strain can be used to produce vitamin A palmitate through whole-cell transformation of vitamin A and palmitic acid. The Bacillus subtilis CS1802 of the present invention is derived from traditional natural fermented food and is a microorganism generally recognized as safe. The strain can be easily cultured and preserved. The highest content of vitamin A palmitate obtained through whole-cell transformation of vitamin A and palmitic acid is 15.35 mg/L. The highest transformation efficiency is 76.75%. The strain provides a new path for enzymatic synthesis of vitamin A palmitate and has important application prospects.

Abstract: The present invention relates to a strain for producing chitinase and application thereof. The class of the strain is named Streptomyces diastaticus CS1801 and the preservation number thereof is CCTCC NO: M2018263. The Streptomyces diastaticus CS1801 of the present invention is derived from naturally fermented prawn paste. By fermentation of prawns, the enzyme activity of the chitosan is as high as 57.3 U/L and the content of chitooligosaccharides is 0.58 mol/L. The present invention provides a new method for producing chitooligosaccharides and has a good application prospect.

Abstract: A stress-strain curve simulation method, for calculating a simulated stress-strain curve of a test object sandwiched between a mass block and a testing platform, the method comprises: obtaining a first acceleration curve associated with a plurality of pieces of acceleration data of the mass block and a second acceleration curve associated with a plurality of pieces of acceleration data of the testing platform; extracting a part of the first acceleration curve and a part of the second acceleration curve to obtain a first valid curve and a second valid curve; obtaining an object strain curve according to the first valid curve and the second valid curve; calculating an object stress curve based on the first valid curve and a contact area between the mass block and the test object; and calculating the simulated stress-strain curve based on the object strain curve and the object stress curve.

Abstract: A wall-mounted magnetic level gauge for material storage containers, the magnetic level gauge comprises: A magnetic displacement assembly, which is located on the sidewall of the material storage container and generates a mechanical displacement in response to the level of a material in the material storage container. It further includes a magnetic sensor assembly, comprising a protective housing, a magnetoresistive chip, and a processing module located within the protective housing. The protective housing is fixed on the side wall of the material storage container. The magentoresistive chip is located at a side of the processing module facing a magnet displacement assembly. The magnetic sensor assembly is used to sense a magnetic field produced by the magnet displacement assembly to determine the level of the material in the material storage container. The magnet displacement assembly displaces the magnet according to the level of the material.

Abstract: This invention describes a magnetoresistive inertial sensor chip, comprising a substrate, a vibrating diaphragm, a magnetic field sensing magnetoresistor and at least one permanent magnet thin film. The vibrating diaphragm is located on one side surface of the substrate. The magnetic field sensing magnetoresistor and the permanent magnet thin film are set on the surface of the vibrating diaphragm displaced from the base of the substrate. A contact electrode is also arranged on the surface of the vibrating diaphragm away from the base of the substrate. The magnetic field sensing magnetoresistor is connected to the contact electrode through a lead. The substrate comprises a cavity formed through etching and either one or both of the magnetic field sensing magnetoresistors and the permanent magnet thin film are arranged in a vertical projection area of the cavity in the vibrating diaphragm portion.

Abstract: A lapping method of a MAMR head slider includes a first lapping process: controlling the lapping plate to spin at a first speed, and controlling the MAMR head slider to move at a first moving speed, and applying a first force to the MAMR head slider; and a second lapping process: controlling the lapping plate to spin at a second speed that is lower than the first speed, and controlling the MAMR head slider to move at a second moving speed that is lower than the first moving speed, and applying a second force that is lower than the first force to the MAMR head slider; and the second lapping process includes a final lapping process section, and the second force in the final lapping process being zero. In such a way, lapping marks on the ABS are reduced to improve the roughness and the reliability.

Abstract: A method for assessing transportation risk is adapted to an object transported by a vehicle. The method comprises disposing a sensor on a floor of the vehicle to generate and collect a vibration signal, with the floor being configured to carry the object, a computing device performs a time-domain processing procedure according to the vibration signal to output a first data, performs a frequency-domain processing procedure according to the first data to output a second data, performs a risk assessing procedure to output a risk level according to the second data and a reference data, wherein the second data comprises an actual vibration intensity and an actual vibration duration and the reference data comprises a reference vibration intensity and a reference vibration duration.

Abstract: A sliding sleeve opening tool includes an engaging element, a ball seat and a guiding head connected in sequence, as disclosed herein. The engaging element includes at least two elastic pawls uniformly disposed in a circumferential direction and at least one engaging part disposed on an external circumferential surface of an elastic pawl, and the engaging element is further provided with a first fluid channel which runs through the engaging element. The ball seat is provided with a second fluid channel which runs through the ball seat, and within the second fluid channel a taper hole section for bearing a sealing ball is disposed, the second fluid channel being in communication with the first fluid channel. The guiding head is provided with a third fluid channel which runs through the guiding head, and the third fluid channel is in communication with the second fluid channel.

Abstract: The invention relates to a GDSL lipase, genetically-engineered bacteria and an application thereof. The GDSL lipase is derived from Streptomyces diastaticus CS1801 and its amino acid sequence is as shown in SEQ ID NO.2. After construction of a genetically-engineered bacterium strain, a GDSL lipase is generated through fermentation. Through this enzyme, vitamin A and palmitic acid are converted to produce vitamin A palmitate. The content of the vitamin A palmitate obtained from the conversion is 16.35 mg/L at most. The conversion efficiency is 81.75% at most. This lipase provides a new path to synthesize vitamin A palmitate by the enzymatic method and has an important application prospect.

Abstract: A device for perforating, packing, and fracturing and a tubing string comprising the device are disclosed, wherein the device comprises an upper connector, a nozzle sleeve, a mandrel, a packer, a lower connector, a first inner sleeve provided inside the upper connector, and a second inner sleeve provided inside the nozzle sleeve, further wherein the upper connector is provided with a fracturing hole, and a nozzle is provided at the nozzle sleeve.