Abstract: A probe for use with an imaging system, including a scanning device configured to receive a first light beam from a light source, a beam-divider configured to split the first light beam into a plurality of second light beams, and a focusing device configured to focus each of the second light beams on respective locations in an object of interest is disclosed.

Abstract: A probe for use with an imaging system, including a scanning device configured to receive a first light beam from a light source, a beam-divider configured to split the first light beam into a plurality of second light beams, and a focusing device configured to focus each of the second light beams on respective locations in an object of interest is disclosed.

Abstract: TEMPERATURE MEASUREMENTS ARE CRITICAL TO VARIOUS ENERGY BASED THERAPEUTIC SYSTEMS, INCLUDING LASER, LIGHT, ELECTROMAGNETIC WAVE, AND HIGH INTENSITY FOCUSED ULTRASOUND BASED THERAPEUTIC SYSTEMS. THIS INVENTION DISCLOSES TECHNIQUES, APPARATUS AND METHODS FOR TEMPERATURE MEASUREMENTS OF SURGICAL TARGETS DURING VARIOUS THERAPEUTIC INTERVENTIONS WITH PHOTOACOUSTIC METHODS, ESPECIALLY WHEN DYNAMIC TEMPERATURE PULSES ARE GENERATED BY SELECTIVE PHOTOTHERMOLYSIS.

Abstract: The present invention relates to a selective photothermolysis device comprising: a tunable radiation source configured to emit radiation; a patient interface comprising a radiation delivery unit configured to deliver the radiation to a tissue, and an ultrasonic detector for detecting photoacoustic waves excited by the radiation from one or more surgical targets in the tissue; and a control system configured to acquire characteristics of the tissue and one or more surgical targets based on measurements on detected photoacoustic waves, determine optimal characteristics of the tunable radiation source for optimal surgical outcome on one or more surgical targets in the tissue, prescribe characteristics and optimal characteristics, and adjust the tunable radiation source for optimal surgical outcome based on the optimal characteristics, and methods applicable to the device.

Abstract: A laser with a wide continuous wavelength tuning range is desirable for optimized selective photothermolysis (SP) laser surgeries that treat light-absorptive lesions and unwanted pigments in human tissue with minimal collateral damages. However, current SP laser surgical systems are limited to a few lasing lines including 1064 nm by Nd:YAG, 755 nm by Alexandrite, 694 nm by Ruby, and 532 nm by second harmonic generation of 1064 nm. This invention discloses techniques to implement a high power, tunable optical parametric oscillator (OPO) system for demanding SP applications such as laser tattoo removal. In addition to wavelength tuning, the OPO laser system's output pulse energy, pulse duration, and pulse-train duration are also adjustable by tuning the pump laser pulse energy, pump laser pulse duration, and pump laser pulse-train duration for optimizing SP laser surgical outcomes.

Abstract: A laser with a wide continuous wavelength tuning range is desirable for optimized selective photothermolysis (SP) laser surgeries that treat light-absorptive lesions and unwanted pigments in human tissue with minimal collateral damages. However, current SP laser surgical systems are limited to a few lasing lines including 1024 nm by Nd:YAG, 755 nm by Alexandrite, 694 nm by Ruby, and 532 nm by second harmonic generation of 1064 nm. This invention discloses techniques to implement a high power, tunable optical parametric oscillator (OPO) system for demanding SP applications such as laser tattoo removal. In addition to wavelength tuning, the OPO laser system's output pulse energy, pulse duration, and pulse-train duration are also adjustable by tuning the pump laser pulse energy, pump laser pulse duration, and pump laser pulse-train duration for optimizing SP laser surgical outcomes.

Abstract: A method for fast high-resolution deep photoacoustic tomography of action potentials in brains is provided herein. The method may utilize a high-speed, high-spatial-resolution, deep-penetration photoacoustic computed tomography (PACT) system for real-time imaging of action potentials.

Abstract: A probe for use with an imaging system, including a scanning device configured to receive a first light beam from a light source, a beam-divider configured to split the first light beam into a plurality of second light beams, and a focusing device configured to focus each of the second light beams on respective locations in an object of interest is disclosed.

Abstract: A probe for use with an imaging system, including a scanning device configured to receive a first light beam from a light source, a beam-divider configured to split the first light beam into a plurality of second light beams, and a focusing device configured to focus each of the second light beams on respective locations in an object of interest is disclosed.

Abstract: SELECTIVE PHOTOTHERMOLYSIS (SP) IS A PRECISE PULSED-LIGHT MICROSURGERY METHOD, DESCRIBED BY ANDERSON AND PARRISH IN A PAPER PUBLISHED BY SCIENCE IN 1983 FOR TREATING LIGHT-ABSORPTIVE LESIONS AND UNWANTED PIGMENTS IN HUMAN TISSUE WITH MINIMAL COLLATERAL DAMAGES. LIGHT SOURCE WITH TUNABLE WAVELENGTH FOR SP IS THE MOST DESIRABLE FEATUER. HOWEVER, SUCH A LIGHT SOURCE IS NOT YET AVAILABLE. IN ADDITION, LIGHT PULSE-WIDTH AND LIGHT PULSE ENERGY ARE CRITICAL FOR SP SURGICAL OUTCOME. THIS INVENSION DISCLOSES TECHNIQUES, APPARATUS AND METHODS FOR OPTIMIZING SP SURGICAL OUTCOME. THE SAME TECHNIQUES APPLY TO SP SURGICAL SYSTEMS USING OTHER RADIATION SOURCES. SOME TECHNIQUES APPLY TO GENERAL SURGICAL SYSTEMS THAT HEAT UP LESIONS IN TISSUE, INCLUDING HIGH-INTENSITY-FOCUSED-ULTRASOUND THERAPIES.

Abstract: A method for fast high-resolution deep photoacoustic tomography of action potentials in brains is provided herein. The method may utilize a high-speed, high-spatial-resolution, deep-penetration photoacoustic computed tomography (PACT) system for real-time imaging of action potentials.

Abstract: A probe for use with an imaging system, including a scanning device configured to receive a first light beam from a light source, a beam-divider configured to split the first light beam into a plurality of second light beams, and a focusing device configured to focus each of the second light beams on respective locations in an object of interest is disclosed.

Abstract: A probe for use with an imaging system, including a scanning device configured to receive a first light beam from a light source, a beam-divider configured to split the first light beam into a plurality of second light beams, and a focusing device configured to focus each of the second light beams on respective locations in an object of interest.

Abstract: A probe for use with an imaging system, including a scanning device configured to receive a first light beam from a light source, a beam-divider configured to split the first light beam into a plurality of second light beams, and a focusing device configured to focus each of the second light beams on respective locations in an object of interest.