Abstract: The present disclosure relates to compositions comprising collagen 7 and methods of using the same to treat DEB.

Abstract: A method, apparatus, and computer-readable storage medium for predicting the affinity of an antibody sequence for an antigen sequence. The method includes obtaining antigen sequence information and antibody sequence information comprising light chain and heavy chain sequence information. Sequence features are extracted from the antigen sequence, light chain sequence, and heavy chain sequence. These extracted features are fused to obtain fused sequence features, which are then processed using a fully connected neural network. The processing determines an affinity detection result representing the affinity of the antibody sequence for the antigen sequence. This computational approach enables efficient prediction of antibody-antigen binding affinities for applications in therapeutic antibody development and immunological research.

Abstract: A forward and reverse cleaning brush with water spraying function, comprising a shell, a water spraying heating mechanism, a power mechanism, a transmission component and a cleaning brush disc, wherein the water spraying heating mechanism is arranged in the shell, the power mechanism is arranged in the shell, the transmission component is arranged at the front end of the shell, and the front end of the transmission component extends out of the shell, the cleaning brush disc is detachably arranged at the front end of the transmission component, the power mechanism and the transmission component cooperate to drive the cleaning brush disc to rotate.

Abstract: An immunogenicity prediction model training method includes constructing an immunogenicity prediction model that includes a binding prediction sub-model, a presentation prediction sub-model, and an immunogenicity prediction sub-model, the binding prediction sub-model being configured to predict binding between an epitope and a major histocompatibility complex (MHC), the presentation prediction sub-model being configured to predict cell membrane presentation of an antigenic peptide-major histocompatibility complex (pMHC) molecular complex, and the immunogenicity prediction sub-model being configured to predict immunogenicity of the pMHC; inputting a first sample pair into the immunogenicity prediction model to obtain a sample immunogenicity prediction result, the first sample pair including a first sample epitope sequence and a first sample MHC sequence, and the first sample pair being provided with a first sample immunogenicity label; and training the immunogenicity prediction model with the first sample immu

Abstract: Provided are an adaptive control electromagnetic induction energy harvesting method and system for a power transmission line.

Abstract: The present disclosure relates to an integrated hydraulic power device and a fire truck. The integrated hydraulic power device includes: an integrated valve including a valve body having an internal flow passage structure, a first mounting end and a second mounting end; a motor fixedly arranged at the first mounting end; a hydraulic oil tank fixedly arranged at the second mounting end; and a hydraulic pump located within the hydraulic oil tank and in drive connection with the motor, wherein the hydraulic pump has an oil suction port for drawing oil from the hydraulic oil tank, and the internal flow passage structure is communicated with the hydraulic oil tank and the hydraulic pump.

Abstract: An anti-collision simulation device and a radiotherapy system relate to the technical field of medical equipment. The anti-collision simulation device is applied to a radiotherapy device, and includes a supporting frame and a simulation rod rotatably connected to the supporting frame. A space enclosed by a rotation track of the simulation rod is matched with a space in a therapy cabin of the radiotherapy device. The supporting frame includes a fixing frame and a movable frame. The fixing frame is fixedly installed relative to the radiotherapy device. The simulation rod is rotatably connected to the movable frame, and the movable frame is able to move relative to the fixing frame, so as to enable the simulation rod to be located at different positions.

Abstract: The application provides a modification of gas density relay, a gas density relay with online self-check function and its check method for high-voltage and medium-voltage electrical equipment. The gas density relay includes a gas density relay body, a gas density sensor, a pressure regulating mechanism, a valve, an online check contact signal sampling unit and an intelligent control unit. The pressure is increased or decreased by the pressure regulating mechanism to enable the contact action of the gas density relay body. The contact action is transmitted to the intelligent control unit through the online check contact signal sampling unit. The intelligent control unit detects the alarm and/or blocking contact signal operating value and/or return value of the gas density relay body according to the density value of the contact action; the check of the gas density relay can be completed without maintenance personnel on site.

Abstract: An integrated valve is made by a method for designing and manufacturing a valve body of the integrated valve. The method for designing the valve body of the integrated valve includes: determining an internal flow channel structure of a valve body model of the integrated valve according to a hydraulic function implemented by the integrated valve; determining a position and a size of respective mounting structures, matched with the external devices, in the valve body model; determining a work structure of the valve body model according to the internal flow channel structure, and the position and the size of respective mounting structures; determining an internal connection plane of the valve body model, and determining an internal supporting table; and determining an external shell of the valve body model, and connecting the external shell with the work structure and the internal supporting table.

Abstract: The present disclosure relates to an integrated hydraulic power device and a fire truck. The integrated hydraulic power device includes: an integrated valve including a valve body having an internal flow passage structure, a first mounting end and a second mounting end; a motor fixedly arranged at the first mounting end; a hydraulic oil tank fixedly arranged at the second mounting end; and a hydraulic pump located within the hydraulic oil tank and in drive connection with the motor, wherein the hydraulic pump has an oil suction port for drawing oil from the hydraulic oil tank, and the internal flow passage structure is communicated with the hydraulic oil tank and the hydraulic pump.

Abstract: A device for realizing the splicing of an array fiber and a large-size quartz end cap comprises a carbon dioxide laser, a light splitter, a light beam shaper, a high reflectivity mirror, an image detection module, an array fiber and a carrier thereof, a large-size quartz end cap and a carrier thereof, a stepping motor, a thermodetector, and a computer; a laser beam emitted by the carbon dioxide laser is divided into two light beams through a light splitter, after the two light beams respectively pass through the beam shaper and the high reflectivity mirror, two strip-shaped light spots with uniform power density are integrally formed to heat a splicing face of the large-size quartz end cap, a uniform temperature field of a target splicing area is achieved through indirect heating and heat conduction.

Abstract: Embodiments of this application provide a method and apparatus for determining antigenic specificity. The method includes acquiring double-stranded biological information of a cell receptor; performing word coding processing on the double-stranded biological information to obtain an amino acid word sequence, the amino acid word sequence comprising an amino acid word representation; performing feature extraction on the cell receptor based on the amino acid word sequence with a pre-trained amino acid sequence prediction model to obtain an amino acid sequence representation of the cell receptor, the amino acid prediction model being trained with masked sample data; and determining the antigenic specificity of the cell receptor based on the amino acid sequence representations.

Abstract: An antigen prediction method including inputting genetic information, sequence information, and three-dimensional structure features of an immune cell receptor into an antigen prediction model, performing, by the antigen prediction model, feature extraction on the genetic information and the sequence information to obtain genetic features and sequence features of the immune cell receptor, integrating, by the antigen prediction model, the genetic features, the sequence features, and the three-dimensional structure features to obtain receptor features of the immune cell receptor, performing, by the antigen prediction model, full connection and normalization on the receptor features to output a probability of the immune cell receptor being associated with each candidate antigen of a plurality of candidate antigens, and determining, based on the probability of the immune cell receptor being associated with each candidate of the plurality of candidate antigens, an antigen binding to the immune cell receptor from t

Abstract: The present disclosure relates to a shielding device and an installation method thereof. The shielding device includes: a bottom plate; a first sidewall, a bottom end of the first sidewall being inserted into the bottom plate; a second sidewall, a bottom end of the second sidewall being inserted into the bottom plate; a top cover, the top cover having one side rotatably connected to the first sidewall and the other side inserted into the second sidewall; a front door connected to respective one ends of the bottom plate, the first sidewall, the second sidewall, and the top cover; and a rear plate connected to respective other ends of the bottom plate, the first sidewall, the second sidewall, and the top cover.

Abstract: The application provides an electrical system with online sampling and check function and its check method for high-voltage and medium-voltage electrical equipment, including electrical equipment, gas density relay, gas density sensor, valve, pressure regulating mechanism, online check contact signal sampling unit and intelligent control unit. The pressure is increased or decreased by the pressure regulating mechanism to enable the contact action of the gas density relay of electrical equipment. The contact action is transmitted to the intelligent control unit through the online check contact signal sampling unit. The intelligent control unit detects the alarm and/or blocking contact signal operating value and/or return value according to the density value of the contact action; the check of the gas density relay can be completed without maintenance personnel on site, which greatly improves the reliability of the power grid and the work efficiency, and reduces the O&M cost.

Abstract: An aerial work platform for a fire fighting vehicle includes: a carrying component; a work platform body mounted on the carrying component and swingable relative to the carrying component to adjust the levelness of the work platform body; a hydraulic actuating element connected to the carrying component and the work platform body, respectively, and configured to drive the work platform body to swing relative to the carrying component; and a hydraulic power unit including a hydraulic pump and a first reversing valve fluidly connected to the hydraulic pump, the first reversing valve being fluidly connected to the hydraulic actuating element, the hydraulic power unit including a first component, the first component being formed with a first pump cavity accommodating a pumping component of the hydraulic pump and a first reversing valve cavity accommodating a valve core of the first reversing valve.

Abstract: A quick-installation soundproof cabin includes a soundproof cabin frame, an end sealing assembly, and a quick-installation mechanism located between the soundproof cabin frame and the end sealing assembly. The quick-installation mechanism includes a supporting body located at a bottom end of the soundproof cabin frame, and the supporting body is protruded towards a direction close to the end sealing assembly from the bottom end of the soundproof cabin frame, to form a supporting structure that is suspended, and the end sealing assembly is configured to be placed on the supporting structure and turned over to an assembly position mated with the soundproof cabin frame. The assembly between the end sealing assembly and the soundproof cabin frame is convenient and efficient.

Abstract: A high anti-vibration gas density monitor is provided, including a monitor enclosure, a signal control mechanism, and an indication value display mechanism independent from the signal control mechanism which are provided in the monitor enclosure. The signal control mechanism includes at least one corrugated pipe, a sealed compensation chamber, a signal generator, and a signal regulation mechanism. The corrugated pipe is perpendicular to a side wall of a control casing. The monitor enclosure includes an independent sealed compartment used to mount the indication value display mechanism. The sealed compartment is filled with anti-vibration oil, or is hermetically filled with gas. The indication value display mechanism includes a Bourdon tube, a base, an end holder, a movement, a pointer, and a dial.

Abstract: A method and system of casting an integral multi-way valve based on 3D printing belong to the technical field of valve casting. The casting method and system determine, according to structural parameters of an integral multi-way valve to be cast, a plurality of ingates on a plurality of layers, a plurality of runners connecting the ingates on each layer, and a sprue connecting the plurality of runners, and an integral sand mold is printed by using the 3D printing technology to realize a multi-layer composite casting method and a corresponding casting system.