Abstract: A massage device having an adjustable massage depth. The massage device comprising a driving device, a crank, a connecting rod, and a massage head assembly, wherein one end of the connecting rod is connected to the crank, and the other end thereof is connected to the massage head assembly; the driving device rotate the crank, and the massage head assembly is driven by means of the connecting rod to perform a massage; and one end of the connecting rod is connected to the crank by means of a movable connecting assembly. The massage device further comprises an adjustment assembly to move the movable connecting assembly, and the movement of the movable connecting assembly enables the distance between the connecting position of the connecting rod and the crank and the rotation center axis to change, so as to adjust the massage depth of the massage head assembly.

Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4, R6, X1, and X2 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising compounds of formula (I).

Abstract: The present invention provides a beauty instrument, comprising: a housing with vents therethrough as an air inlet or air outlet; a control circuit board in the housing; a light source assembly in the housing and electrically connected with the control circuit board; and a thermoelectric cooling assembly. The thermoelectric cooling assembly comprises: a thermoelectric cooler, a heat sink, a fan, and a heat transfer assembly. The heat transfer assembly comprises a VC or an ALVC or an Aluminum Heat Pipe. The heat transfer assembly is thermally connected between the heat sink and the hot side of thermoelectric cooler. A front end of the beauty instrument has a light outlet surface; the cold side is connected to and cool the light outlet surface, or the cold side serves as the light outlet surface, thereby, the light outlet surface is able to cool skin in contact.

Abstract: A platform for testing the excavation resistance of a small-sized backhoe excavator is provided. The testing platform comprises a bucket, a mechanical arm device, a measuring device, a workbench frame, and a control device. The bucket is hinged to the mechanical arm device, which is fixed on the workbench frame; the control device is electrically connected to the measuring device, data acquired by the measuring device is used to construct a force balance equation, and through force analysis, excavation resistance is obtained.

Abstract: A technique suggests resources within a particular environment. The technique operates by receiving a query via a search interface presentation, and using a prefix tree data structure to retrieve candidate resource descriptors that match the query. The candidate resource descriptors are data items that describe different types of candidate resources. The technique further includes: generating feature information that describes the candidate resource descriptors; using a machine-trained ranking model to generate scores associated with the candidate resource descriptors, based on the feature information; sorting the candidate resource descriptors based on the scores, to provide sorted resource descriptors; and generating output information that represents a selected set of resource descriptors drawn from the sorted resource descriptors, for presentation via the search interface presentation.

Abstract: A tension device for an elevator car, an elevator car, and an elevator system. The elevator car has a first side portion and a second side portion opposite to each other and a rear side portion opposite to a car door, and an elevator counterweight is arranged on a side close to the first side portion, the tension device includes a tension member, and a first end and a second end of the tension member are fixed to a first position and a second position on the elevator car respectively, to provide a first tensile force acting on the elevator car, and the first tensile force is substantially parallel to a longitudinal direction of the elevator car at the top of the elevator car and directed towards the rear side portion.

Abstract: A method includes performing or skipping performing measurement on a target frequency channel number depending on whether a distance between a terminal device and at least one cell at the target frequency channel number satisfies a distance condition. The target frequency channel number is different from a first frequency channel number, the first frequency channel number is a frequency channel number of a serving cell of the terminal device, the target frequency channel number is any one of a plurality of frequency channel numbers, and the plurality of frequency channel numbers are frequency channel numbers indicated by system information.

Abstract: An anti-BDCA2 antibody-drug conjugate and the use thereof. The anti-BDCA2 antibody-drug conjugate comprises: an antibody targeting BDCA2 or an antigen-binding fragment thereof, a linker fragment (L), and a glucocorticoid molecule. Also provided are a preparation method for and the use of the antibody-drug conjugate.

Abstract: Water-in-oil (W/O) emulsion compositions having freeze-thaw stability are provided which include water, at least one hydrocarbon solvent, at least one nonionic emulsifier, and at least one freeze-thaw stabilizer which either prevents breaking of the emulsion after a freeze-thaw cycle or enables the emulsion to be re-formed following breaking after a freeze-thaw cycle by simple shaking of the emulsion composition. Preferred freeze-thaw stabilizers are polyols (e.g., glycerin), sugars (e.g., sucrose), polar aprotic solvents (e.g., dimethyl sulfoxide) and amphoteric compounds (e.g., lauryl dimethyl amine oxide). The freeze-thaw stabilizers are particularly useful in furniture care, shoe care and auto care cleaning and/or polishing products including therein water, hydrocarbon solvent(s), nonionic emulsifier(s) and additives, such as film former(s), surfactant(s), fragrance component(s) and preservative(s).

Abstract: The present disclosure provides a Paenibacillus strain, and a hemostatic polysaccharide produced by same and use thereof. In the present disclosure, a Paenibacillus sp. 1229 has a deposit number of CCTCC NO: M 2022553. A produced exopolysaccharide (EPS) Hemoadhican has a hemostatic function, and can be prepared as a hemostatic material in different dosage forms for different types of hemostasis. The hemostatic material has a high hemostatic speed, no need for applying pressures to the wound for a long time, safety and non-toxicity, desirable biocompatibility, and no requirement of removal after use. The material is suitable for the application of hemostasis in irregular bleeding such as solid organs in vitro or in vivo and diffuse bleeding.

Abstract: An antenna includes a dielectric substrate having a first surface and a second surface opposite to each other, a first conductive plate arranged at the first surface, a second conductive plate arranged at the second surface, and a plurality of metal members sequentially arranged adjacently one after another at the dielectric substrate. A distance between two adjacent metal members among the plurality of metal members is greater than a preset distance, and a projection of an overall shape of the plurality of metal members on the dielectric substrate has an opening.

Abstract: A deep learning-based method for recognizing continuous shovel loading positions in an autonomous loader includes: acquiring laser point cloud data representing surface topography of a stockpile, and processing the laser point cloud data to obtain shovel-loading region features of the stockpile; constructing a model of an actuating mechanism for a loader, performing simulation force analysis on the model of the actuating mechanism and the shovel-loading region features of the stockpile, to obtain shovel-loading position features of the stockpile; analyzing and evaluating the shovel-loading position features of the stockpile to obtain an optimal shovel-loading position feature of the stockpile; and constructing a detection model, acquiring an image of the stockpile to be identified simultaneously, inputting the image of the stockpile to be identified into the detection model for processing, and detecting and adjusting a shovel-loading position of the loader based on the image processing results and the optimal

Abstract: Compounds of Formula (I) or their pharmaceutically acceptable salts can inhibit the G12C, G12D, G12V, and/or G13D mutants of Kirsten rat sarcoma (KRAS) protein and are expected to have utility as therapeutic agents, for example, for treating cancer. The disclosure also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The disclosure also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of cancer and for preparing pharmaceuticals for this purpose.

Abstract: Embodiments of the present disclosure provide an interaction control method, a device and a medium. The method is performed by a controlling device, which is in wireless communication with a controlled device. The method includes: displaying at least two window interfaces in an interaction control scenario, where each window interface corresponds to one screen of the controlled device, and presenting screen content; monitoring an input event generated when an indication cursor of an input device moves from a first window interface to a second window interface, generating input event information of the input event, and sending the input event information to the controlled device, so that the controlled device determines, based on the input event information, that a drag-and-drop operation is performed on a first object; and receiving and displaying image content of the first object being dragged and dropped from a first screen to a second screen.