Abstract: The present application relates to an anti-Nectin-4 antibody, a drug conjugate and a preparation method and use thereof, which can be effectively used for the treatment and/or prevention of Nectin-4 positive tumors, including cancers, such as breast cancer and bladder cancer.

Abstract: A battery includes a plurality of arranged battery cells; and a pressure regulating apparatus, including a body portion and a regulating valve, where the body portion is arranged between adjacent battery cells, a gas pipeline being formed in the body portion, and the regulating valve is arranged in the gas pipeline and configured to regulate pressure in the gas pipeline so as to adjust a gap between adjacent battery cells.

Abstract: The present application relates to an anti-tumor compound and a preparation method and use thereof, and in particular to a compound or a tautomer, a mesomer, a racemate, an enantiomer or a diastereoisomer thereof, or a mixture thereof, or a pharmaceutically acceptable salt thereof, and a preparation method and use thereof.

Abstract: An edge-lit back light unit includes a specular reflector and an edge-lit light guide film positioned above the specular reflector, both configured to provide peak optical distribution and FWHM angle of diffusion along a light propagation direction. A diffuser film above the edge-lit light guide film has a bottom-side that faces the edge-lit light guide film and a top-side that faces away from the edge-lit light guide film, and has a plurality of parallel prism microstructures on the bottom-side, some have an apex direction that is generally along the light propagation direction. The diffuser film has a plurality of parallel prism microstructures on the top-side having an apex direction that is rotated with respect to the apex direction of the plurality of parallel prism microstructures on the bottom-side such that the apex direction of the parallel prism microstructures on the top-side is generally perpendicular to the light propagation direction.

Abstract: A keyboard and an electronic device, wherein the keyboard comprises: a keyboard module comprising a plurality of keycaps and a keyboard body; a body waterproof layer provided with an accommodating part; and a keycap waterproof layer comprising a first bonding part and a second bonding part, wherein each of the keycaps passes through the accommodating part, and the body waterproof layer is connected with the keyboard body; the first bonding part is bonded to a side of each of the keycaps away from the keyboard body, and the second bonding part is bonded to the accommodating part; and the body waterproof layer and the keycap waterproof layer are both an integrally formed structure; the electronic device comprises the keyboard above the a device body, the keyboard is connected with the device body by a signal.

Abstract: Apparatus and methods for improving optical signal collection in an integrated device are described. A microdisk can be formed in an integrated device and increase collection and/or concentration of radiation incident on the microdisk and re-radiated by the microdisk. An example integrated device that can include a microdisk may be used for analyte detection and/or analysis. Such an integrated device may include a plurality of pixels, each having a reaction chamber for receiving a sample to be analyzed, an optical microdisk, and an optical sensor configured to detect optical emission from the reaction chamber. The microdisk can comprise a dielectric material having a first index of refraction that is embedded in one or more surrounding materials having one or more different refractive index values.

Abstract: A bioprintable material is provided. The bioprintable material includes a hydrogel and microfilaments mixed in the hydrogel. The hydrogel includes a first collagen. The microfilament includes a second collagen. The diameter of the microfilament is ranging from 5 microns to 200 microns. The weight ratio of the microfilaments to the first collagen is ranging from 0.01:1 to 10:1.

Abstract: An optical structure is described for correcting display viewing angle color shift. The optical structure includes a microlens array layer having a first surface and a second surface forming an array of microlenses. A portion of the microlens array layer is formed of a color loading material having a density that results in a desired difference between a color shift at a non-zero viewing angle and a color shift at a zero viewing angle.

Abstract: A polarization splitter-rotator (PSR) is described. The PSR having a silicon nitride based waveguide including a first silicon nitride segment comprising a tapered width in a longitudinal direction and a ridge extending in a transverse direction and an adiabatic coupler coupled with the first silicon nitride segment.

Abstract: An edge-lit back light unit for a backlit display includes a reflector, an edge-lit light guide film, a diffuser film, and a pair of crossed brightness enhancement films with increased efficiency. The diffuser film has an angular light distribution output that is matched to light acceptance angles of the pair of crossed brightness enhancement films to provide increased on-axis brightness without having to increase power to the edge-lit back light unit.

Abstract: Apparatus and methods for improving optical signal collection in an integrated device are described. A microdisk can be formed in an integrated device and increase collection and/or concentration of radiation incident on the microdisk and re-radiated by the microdisk. An example integrated device that can include a microdisk may be used for analyte detection and/or analysis. Such an integrated device may include a plurality of pixels, each having a reaction chamber for receiving a sample to be analyzed, an optical microdisk, and an optical sensor configured to detect optical emission from the reaction chamber. The microdisk can comprise a dielectric material having a first index of refraction that is embedded in one or more surrounding materials having one or more different refractive index values.

Abstract: Apparatus and methods relating to photonic bandgap optical nanostructures are described. Such optical nanostructures may exhibit prohibited photonic bandgaps or allowed photonic bands, and may be used to reject (e.g., block or attenuate) radiation at a first wavelength while allowing transmission of radiation at a second wavelength. Examples of photonic bandgap optical nanostructures includes periodic and quasi-periodic structures, with periodicity or quasi-periodicity in one, two, or three dimensions and structural variations in at least two dimensions. Such photonic bandgap optical nanostructures may be formed in integrated devices that include photodiodes and CMOS circuitry arranged to analyze radiation received by the photodiodes.

Abstract: A polarization splitter-rotator (PSR) is described. The PSR having a silicon nitride based waveguide to split and rotate an optical beam. The silicon nitride based waveguide having a first silicon nitride segment including a first layer and a second layer coupled with the first layer.

Abstract: An optical film for a back light unit that includes an array of light emitting diodes. The optical film includes a substrate, and a plurality of regions of spatially modulated microstructures on at least one side of the substrate. The spatially modulated microstructures have different sizes and/or shapes configured to create a gradient structure within each region. The gradient structure within each region is constructed and arranged to cause more spreading of light when positioned directly above an individual light emitting diode and less spreading of light at locations not directly above an individual light emitting diode. Within the back light unit, the gradient structure converts light beams emitted by the respective light emitting diode at different angles into a more uniform and higher on-axis luminance upon exiting the back light unit.

Abstract: A clothing aroma-enhancing bead composition and a method for preparing same are provided. The clothing aroma-enhancing bead composition includes the following raw materials in percentage by weight: 60-95% of sugar granules, 1.0-20% of liquid essence, and 0.5-20% of silica. The clothing aroma-enhancing bead composition takes the sugar granules as a core, and surfaces of the sugar granules are coated with the liquid essence and the silica. The clothing aroma-enhancing bead composition is attractive in appearance, good in solubility, and simple in production process.

Abstract: A light transmissive structure includes a light transmissive substrate having first and second opposing faces, and an array of microprism elements on the first face. Each microprism element includes a first inclined surface disposed at a first inclined angle relative to the second face, and a second inclined surface disposed at a second inclined angle relative to the second face. The first inclined angle is less than the second inclined angle, and a peak angle between the first inclined surface and second inclined surface is in the range of about 70 degrees to about 100 degrees. The second inclined surface has a convex curvature when viewed from angles perpendicular thereto. The light transmissive structure is configured to receive light from a light source facing the first face in a first direction and redistribute light emerging from the second face in a second direction different from the first direction.

Abstract: A back light unit includes an array of LEDs positioned in rows and columns that emit light from a top surface. A light splitting optical film includes a plurality of inverted pyramids positioned on a first side facing the top surface of the array where each of the plurality of inverted pyramids forms an apex oriented in a direction away from the top surface of the array. A plurality of linear prisms is positioned in a parallel configuration on a second side facing away from the top surface of the array where at least some of the linear prisms form an apex being oriented such that a direction of the apex forms a desired angle with respect to a direction of a row of the array of light emitting diodes.

Abstract: Optical waveguides and couplers for delivering light to an array of photonic elements in a photonic integrated device. The photonic integrated device and related instruments and systems may be used to analyze samples in parallel. The photonic integrated device may include a grating coupler configured to receive light from an external light source and optically couple with multiple waveguides configured to optically couple with sample wells of the photonic integrated device.

Abstract: Optical waveguides and couplers for delivering light to an array of photonic elements in a photonic integrated device. The photonic integrated device and related instruments and systems may be used to analyze samples in parallel. The photonic integrated device may include a grating coupler configured to receive light from an external light source and optically couple with multiple waveguides configured to optically couple with sample wells of the photonic integrated device.

Abstract: A light detection and ranging (LIDAR) system and apparatus including a photonics chip mounted to a substrate, the photonics chip including one or more optical components and one or more electrical components and one or more integrated circuit (IC) chips mounted to the photonics chip to process an electrical signal generated by the one or more optical components and the one or more electrical components, wherein the one or more IC chips are physically separated from the substrate to reduce crosstalk on the LIDAR apparatus.