Abstract: The present invention relates to a steroid compound and a conjugate thereof, and specifically relates to a compound and a conjugate thereof, or a tautomer, a mesomer, a racemate, an enantiomer and a diastereoisomer thereof, or a mixture form thereof, or a pharmaceutically acceptable salt thereof; and a method for preparing the compound and the conjugate thereof and the use thereof.

Abstract: A light emitting diode includes an epitaxial semiconductor layer including an N-type nitride layer, a v-pit emergence layer, a strain adjustment layer, an active layer, and a P-type nitride layer that are sequentially stacked in that order. The active layer has a plurality of barrier layers and a plurality of well layers that are alternatively stacked. The epitaxial semiconductor layer includes a v-pit. The v-pit has an opening that is located at a topmost one of the barrier layers of the active layer, and has a width that is greater than 260 nm. The v-pit emergence layer is doped with carbon (C) at a doping concentration that is no less than 7×1016/cm3. A light emitting device includes the light emitting diode.

Abstract: A light transmissive substrate for transforming a Lambertian light distribution into a batwing light distribution. The light transmissive substrate includes a first surface comprising a plurality of microstructures, and a second surface on a side of the substrate opposite the first surface. The substrate is configured to receive light in a Lambertian distribution from a light source at the first surface and transform the light into a batwing distribution exiting the second surface. The batwing distribution having a peak intensity at about ±30° to about ±60° from X and Y axes, and a minimum intensity at nadir.

Abstract: The present application relates to an anti-tumor compound and a preparation method and use thereof, and in particular to a compound or a tautomer, a mesomer, a racemate, an enantiomer or a diastereoisomer thereof, or a mixture thereof, or a pharmaceutically acceptable salt thereof, and a preparation method and use thereof.

Abstract: A frequency-modulated continuous-wave (FMCW) light detection and ranging (LiDAR) system includes an optical source to direct optical beams towards a target object, and a plurality of return signals are returned to the LiDAR system. The LiDAR system includes a reflective optical component to return a portion of the plurality of optical beams along a return path as a local oscillator (LO) signal, a rotating scanning mirror between the optical source and the target object, and a plurality of optical detectors. The plurality of optical detectors receives and consumes the plurality of return signals. The LiDAR system also includes an optical circuit implemented on a photonics chip that include a plurality of photonics couplers. The plurality of photonics couplers produces a plurality of outputs that are combined by the optical circuit. A signal processing system consumes the outputs.

Abstract: A photonics grating coupler to transmit light in a light detection and ranging (LiDAR) system includes a receiver component adapted to receive light transmitted from an optical source. The photonics grating coupler includes a plurality of light scattering elements arranged in a rectangular pattern, wherein the plurality of light scattering elements comprises a first set of light scattering elements, each light scattering element comprising a first cross section and a first duty cycle and adapted to receive the light from the receiver to produce reflected light. The photonics grating coupler also includes a second set of light scattering elements, each light scattering element comprising a second cross section and a second duty cycle and adapted to transmit the reflected light towards a waveguide coupled to receive the reflected light.

Abstract: The present disclosure relates to a scene pushing method, a scene implementing method, a scene pushing apparatus, a scene implementing apparatus, a terminal, a server, and a system. The scene pushing method is applied to a management terminal, and comprises: sending a scene query request to a cloud scene server, such that the cloud scene server queries, from a plurality of edited scenes, one or more scenes to be pushed, the edited scenes comprising scenes edited by a mobile terminal or a vehicle-mounted terminal of a first user; receiving said one or more scenes to be pushed returned by the cloud scene server; and screening said one or more scenes to be pushed to obtain a target scene, and pushing the obtained target scene to a target vehicle-mounted terminal, the target vehicle-mounted terminal comprising a vehicle-mounted terminal of a second user.

Abstract: The present application relates to an anti-Nectin-4 antibody, a drug conjugate and a preparation method and use thereof, which can be effectively used for the treatment and/or prevention of Nectin-4 positive tumors, including cancers, such as breast cancer and bladder cancer.

Abstract: A battery includes a plurality of arranged battery cells; and a pressure regulating apparatus, including a body portion and a regulating valve, where the body portion is arranged between adjacent battery cells, a gas pipeline being formed in the body portion, and the regulating valve is arranged in the gas pipeline and configured to regulate pressure in the gas pipeline so as to adjust a gap between adjacent battery cells.

Abstract: The present application relates to an anti-tumor compound and a preparation method and use thereof, and in particular to a compound or a tautomer, a mesomer, a racemate, an enantiomer or a diastereoisomer thereof, or a mixture thereof, or a pharmaceutically acceptable salt thereof, and a preparation method and use thereof.

Abstract: An edge-lit back light unit includes a specular reflector and an edge-lit light guide film positioned above the specular reflector, both configured to provide peak optical distribution and FWHM angle of diffusion along a light propagation direction. A diffuser film above the edge-lit light guide film has a bottom-side that faces the edge-lit light guide film and a top-side that faces away from the edge-lit light guide film, and has a plurality of parallel prism microstructures on the bottom-side, some have an apex direction that is generally along the light propagation direction. The diffuser film has a plurality of parallel prism microstructures on the top-side having an apex direction that is rotated with respect to the apex direction of the plurality of parallel prism microstructures on the bottom-side such that the apex direction of the parallel prism microstructures on the top-side is generally perpendicular to the light propagation direction.

Abstract: A keyboard and an electronic device, wherein the keyboard comprises: a keyboard module comprising a plurality of keycaps and a keyboard body; a body waterproof layer provided with an accommodating part; and a keycap waterproof layer comprising a first bonding part and a second bonding part, wherein each of the keycaps passes through the accommodating part, and the body waterproof layer is connected with the keyboard body; the first bonding part is bonded to a side of each of the keycaps away from the keyboard body, and the second bonding part is bonded to the accommodating part; and the body waterproof layer and the keycap waterproof layer are both an integrally formed structure; the electronic device comprises the keyboard above the a device body, the keyboard is connected with the device body by a signal.

Abstract: Apparatus and methods for improving optical signal collection in an integrated device are described. A microdisk can be formed in an integrated device and increase collection and/or concentration of radiation incident on the microdisk and re-radiated by the microdisk. An example integrated device that can include a microdisk may be used for analyte detection and/or analysis. Such an integrated device may include a plurality of pixels, each having a reaction chamber for receiving a sample to be analyzed, an optical microdisk, and an optical sensor configured to detect optical emission from the reaction chamber. The microdisk can comprise a dielectric material having a first index of refraction that is embedded in one or more surrounding materials having one or more different refractive index values.

Abstract: A bioprintable material is provided. The bioprintable material includes a hydrogel and microfilaments mixed in the hydrogel. The hydrogel includes a first collagen. The microfilament includes a second collagen. The diameter of the microfilament is ranging from 5 microns to 200 microns. The weight ratio of the microfilaments to the first collagen is ranging from 0.01:1 to 10:1.

Abstract: A polarization splitter-rotator (PSR) is described. The PSR having a silicon nitride based waveguide including a first silicon nitride segment comprising a tapered width in a longitudinal direction and a ridge extending in a transverse direction and an adiabatic coupler coupled with the first silicon nitride segment.

Abstract: An optical structure is described for correcting display viewing angle color shift. The optical structure includes a microlens array layer having a first surface and a second surface forming an array of microlenses. A portion of the microlens array layer is formed of a color loading material having a density that results in a desired difference between a color shift at a non-zero viewing angle and a color shift at a zero viewing angle.

Abstract: An edge-lit back light unit for a backlit display includes a reflector, an edge-lit light guide film, a diffuser film, and a pair of crossed brightness enhancement films with increased efficiency. The diffuser film has an angular light distribution output that is matched to light acceptance angles of the pair of crossed brightness enhancement films to provide increased on-axis brightness without having to increase power to the edge-lit back light unit.

Abstract: Apparatus and methods for improving optical signal collection in an integrated device are described. A microdisk can be formed in an integrated device and increase collection and/or concentration of radiation incident on the microdisk and re-radiated by the microdisk. An example integrated device that can include a microdisk may be used for analyte detection and/or analysis. Such an integrated device may include a plurality of pixels, each having a reaction chamber for receiving a sample to be analyzed, an optical microdisk, and an optical sensor configured to detect optical emission from the reaction chamber. The microdisk can comprise a dielectric material having a first index of refraction that is embedded in one or more surrounding materials having one or more different refractive index values.

Abstract: Apparatus and methods relating to photonic bandgap optical nanostructures are described. Such optical nanostructures may exhibit prohibited photonic bandgaps or allowed photonic bands, and may be used to reject (e.g., block or attenuate) radiation at a first wavelength while allowing transmission of radiation at a second wavelength. Examples of photonic bandgap optical nanostructures includes periodic and quasi-periodic structures, with periodicity or quasi-periodicity in one, two, or three dimensions and structural variations in at least two dimensions. Such photonic bandgap optical nanostructures may be formed in integrated devices that include photodiodes and CMOS circuitry arranged to analyze radiation received by the photodiodes.

Abstract: A polarization splitter-rotator (PSR) is described. The PSR having a silicon nitride based waveguide to split and rotate an optical beam. The silicon nitride based waveguide having a first silicon nitride segment including a first layer and a second layer coupled with the first layer.