Patents by Inventor Bing Y. Luh

Bing Y. Luh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cephalosporin derivatives
    Publication number: 20020049191
    Abstract: The present invention provides a novel series of cephem derivatives of the general formula I 1
    Type: Application
    Filed: May 29, 2001
    Publication date: April 25, 2002
    Inventors: Dane M. Springer, Bing Y. Luh, Stanley V. D'Andrea, Thomas W. Hudyma, Oak K. Kim
  • Cephalosporin derviatives
    Patent number: 5620969
    Abstract: Novel cephem derivatives represented by the general formula ##STR1## in which the Acyl substituent is a group of the formula ##STR2## wherein Ar is a lipophilic optionally substituted phenyl, naphthyl or pyridyl group; R.sup.1 represents either the residue of a heterocyclic amino acid or a C.sub.2 -C.sub.10 alkyl group substituted by both a carboxyl group and a group of the formula --NR.sup.9 R.sup.10 or ##STR3## in which R.sup.9 and R.sup.10 are each independently hydrogen or C.sub.1 -C.sub.6 alkyl, said C.sub.2 -C.sub.10 alkyl group being optionally interrupted by one or more nitrogen atoms or carbonyl groups, and R.sup.2 and R.sup.3 are each independently hydrogen, alkyl or aminoalkyl are gram-positive antibacterial agents, especially useful in the treatment of diseases caused by methicillin-resistant Staphylococcus aureus (also referred to below as MRSA or methicillin-resistant S. aureus).
    Type: Grant
    Filed: April 25, 1995
    Date of Patent: April 15, 1997
    Assignee: Bristol-Myers Squibb Company
    Inventors: Joanne J. Bronson, Stanley V. D'Andrea, Shelley E. Hoeft, John D. Matiskella, Peter F. Misco, Jr., Bing Y. Luh, Dane M. Springer, Yasutsugu Ueda, John A. Wichtowski
  • Antiviral (phosphonomethoxy)methoxy purine/pyrimidine derivatives
    Patent number: 5386030
    Abstract: The present invention concerns nucleotide analogs and their compositions and use. In particular it relates to novel (phosphonomethoxy) methoxy purine/pyrimidine derivatives.
    Type: Grant
    Filed: February 11, 1993
    Date of Patent: January 31, 1995
    Assignees: Institute of Organic Chemistry and Biochemistry of the Academy of Science of the Czech Republic, Rega Stichting v.z.w.
    Inventors: Choung U. Kim, John C. Martin, Bing Y. Luh, Peter F. Misco
  • Thymidine derivatives and therapeutic method of use
    Patent number: 5306722
    Abstract: Thymidine kinase inhibitor of formula I ##STR1## in which R is C.sub.1-6 alkyl or AR(CH.sub.2).sub.n --, wherein Ar represents phenyl optionally substituted with one to five same or different halogen, C.sub.1-6 alkyl or C.sub.1-6 alkyloxy; and n equals one to six.A further aspect of the present invention provides a method of inhibiting viral thymidine kinase. Yet another aspect of the invention relates to treating herpes simplex viral infections in mammals. Yet another aspect of the invention provides a pharmaceutical formulation.
    Type: Grant
    Filed: September 2, 1992
    Date of Patent: April 26, 1994
    Assignee: Bristol-Myers Squibb Company
    Inventors: Choung U. Kim, Bing Y. Luh, Peter F. Misco
  • Antiviral (phosphonomethoxy) methoxy purine/pyrimidine derivatives
    Patent number: 5208221
    Abstract: The present invention concerns nucleotide analogs and their compositions and use. In particular it relates to novel (phosphonomethoxy) methoxy purine/pyrimidine derivatives.
    Type: Grant
    Filed: November 29, 1990
    Date of Patent: May 4, 1993
    Assignee: Bristol-Myers Squibb Company
    Inventors: Choung U. Kim, John C. Martin, Bing Y. Luh, Peter F. Misco