Abstract: Disclosed are a quantum chip and a fabrication method therefor. The quantum chip includes a base substrate on which signal transmission lines are formed; and at least one insulating substrate located on the base substrate, where a qubit and a through hole penetrating through the insulating substrate are formed on the insulating substrate, a metal piece is formed in the through hole, and two ends of the metal piece are electrically connected to the signal transmission lines and the qubit, respectively.

Abstract: A method, electronic device, and a computer readable medium for managing backup data that includes determining an expiration time of backup data in a data set to be backed up in a source storage device, and determines a priority of the backup data to be migrated in a migration operation to be performed based on the expiration time. The method may also include migrating backup data with the same priority in the data set to be backed up to a target storage device to reduce a write amplification factor of a storage device, and prolong the service life of the storage device.

Abstract: The invention relates generally to a silvestrol molecule activated with a leaving group. The invention further relates generally to an antibody-drug conjugate comprising an antibody conjugated by a linker to one or more silvestrol drug moieties and methods of treatment.

Abstract: The present application provides a storage-stable polyisocyanate composition and a preparation method. The polyisocyanate composition is obtained by selecting one or more diisocyanate from aliphatic diisocyanates and alicyclic diisocyanates, and reacting same with an alcohol compound; the polyisocyanate composition contains an isocyanurate group, a uretdione group, a carbamate group, and an allophanate group; within the polyisocyanate composition, the molar ratio of the carbamate group/(uretdione group+isocyanurate group) is 0.01-0.2, and preferably 0.01-0.1. Compared to existing techniques, the present application has the advantage of a noticeable increase in system viscosity of uretdione polyisocyanate during storage. With the present application, by means of controlling the ratio of the carbamate group/(uretdione group+isocyanurate group) within the system, the increase in viscosity of a product during storage is inhibited, thereby improving the storage stability of the product.

Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.

Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.

Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.

Abstract: A stable dispersant and an application thereof in preparing copolymer polyols, the preparation method for the stable dispersant including the steps of 1) contacting a polyol with a dianhydride compound for reaction so as to prepare an adduct; 2) performing a ring-opening addition reaction on the adduct obtained in step 1) and an epoxy compound to prepare a stable dispersant; the dianhydride compound does not contain a double bond that may copolymerize with an olefinically unsaturated monomer, while the epoxy compound contains a double bond that may copolymerize with an olefinically unsaturated monomer, the polyol is a polyester polyol and/or a polyether polyol, preferably being a polyether polyol. The stable dispersant obtained by means of the described preparation method has a multi-active site anchoring function, and is applied to the synthesis of copolymer polyols to obtain copolymer polyols having relatively uniform particle size.

Abstract: A macromonomeric stabilizer, a preparation method thereof, a method for preparing a polymeric polyol using same, and the polymeric polyol prepared. Also disclosed are a soft polyurethane foam obtained by foaming a composition of the polymeric polyol prepared and a polyisocyanate, and a molded product comprising the soft polyurethane foam. The preparation method of the macromonomeric stabilizer comprises the following steps: reacting a polyol with a tricarboxylate not comprising a polymerizable ethylenically unsaturated double bond, or a derivative thereof, to form an adduct; and reacting the resulting adduct with an epoxide comprising a polymerizable ethylenically unsaturated double bond. The macromonomeric stabilizer of the present invention has a low viscosity, comprises a plurality of active sites, and can be directly used in subsequent reactions. The preparation method of the macromonomeric stabilizer can be carried out under normal pressure, without the need for end-blocking with ethylene oxide.

Abstract: Disclosed a connecting structure including a coating component provided with a storage cavity and a first through hole, an expansion component provided with a second through hole and a first fastener. A part of the expansion component is stored in the storage cavity; the expansion component has a rotary state and a fixed state relative to the coating component; when the expansion component is in the rotary state, the expansion component can be rotated relative to the coating component; the first fastener can pass through the first through hole and extend into the second through hole to make the expansion component expand; the outer surface of the expansion component is pressed against the inner surface of the coating component to fix the expansion component in the coating component; and the expansion component is in the fixed state relative to the coating component.

Abstract: A thin-profile ultrasonic sensor includes a piezoelectric material layer having a first surface and a second surface, a plurality of thin film transistors (TFTs) on the first surface, and an electrode layer on the second surface. The first surface and the second surface are on opposite sides facing away from each other. The piezoelectric material layer is configured as a substrate to support the plurality of TFTs, no other substrate being required. The piezoelectric material layer is configured to transmit and receive ultrasonic signals.

Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.

Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.

Abstract: An ultrasonic sensing device includes an ultrasonic signal transmitting element and an ultrasonic signal receiving element. The ultrasonic signal transmitting element is configured to produce ultrasonic waves. The ultrasonic signal receiving element is configured to receive ultrasonic waves. The ultrasonic signal transmitting element and the ultrasonic signal receiving element are positioned at a same plane. A distance between the ultrasonic signal transmitting element and the ultrasonic signal receiving element is adjustable. The ultrasonic signal transmitting element is capable of emitting ultrasonic waves having a conical shape.

Abstract: An ultrasonic sensing device is foldable and includes two bracket portions rotatably connected and an ultrasonic sensor on each bracket portion. The ultrasonic sensor includes a flexible circuit board carrying an ultrasonic signal transmitting element and an ultrasonic signal receiving element. The ultrasonic signal transmitting element is mounted to one of the two bracket portions, and the ultrasonic signal receiving element is mounted to other of the two bracket portions. The ultrasonic signal transmitting element is capable of rotating to the ultrasonic signal receiving element by opening and closing the two bracket portions.

Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.

Abstract: The invention relates generally to a silvestrol molecule activated with a leaving group. The invention further relates generally to an antibody-drug conjugate comprising an antibody conjugated by a linker to one or more silvestrol drug moieties and methods of treatment.

Abstract: The present invention relates to anti-CLL-1 antibodies including anti-CLL-1 antibodies comprising a CLL-1 binding domain and a CD3 binding domain (e.g., anti-CLL-1/CD3 T cell dependent bispecific (TDB) antibody) and methods of using the same.

Abstract: The invention relates generally to a silvestrol molecule activated with a leaving group. The invention further relates generally to an antibody-drug conjugate comprising an antibody conjugated by a linker to one or more silvestrol drug moieties and methods of treatment.

Abstract: The present invention is directed to compositions of matter comprising immunoconjugates comprising an anti-CD79b antibody comprising: (i) an HVR-L1 sequence of KASQSVDYEGDSFLN (SEQ ID NO: 194), (ii) an HVR-L2 sequence of AASNLES (SEQ ID NO: 195), (iii) an HVR-L3 sequence of QQSNEDPLT (SEQ ID NO: 196), (iv) an HVR-H1 sequence of GYTFSSYWIE (SEQ ID NO: 202), (v) an HVR-H2 sequence of GEILPGGGDTNYNEIFKG (SEQ ID NO: 203), and (vi) an HVR-H3 sequence of TRRVPIRLDY (SEQ ID NO: 204) and to methods of using those compositions of matter for the treatment of hematopoietic tumor in mammals.