Abstract: The present disclosure provides a fruit tree pollination method for preventing and controlling an Erwinia amylovora-caused disease, belonging to the technical field of plant protection and fruit tree cultivation. The method includes: (1) mixing a pollen nutrient solution with a bactericide, and adding refined pollen to obtain a pollen suspension; alternatively, mixing a bactericide powder with the refined pollen and a filler to prepare a mixed powder; where the bactericide is any one or more selected from the group consisting of albendazole, an antibacterial polypeptide, and zhongshengmycin; and (2) conducting pollination on a fruit tree with the pollen suspension or the mixed powder in a flowering stage.