Abstract: A method and device for advancing a guidewire past a calcified leaflet of a heart valve are described. A dual guidewire device includes a primary guidewire, a secondary guidewire, and a sheath. The primary guidewire is configured to advance past a heart valve while the secondary guidewire is configured to pull open the calcified leaflet of the heart valve while the primary guidewire advances past the heart valve. The catheter can contain both the primary guidewire and the secondary guidewire.

Abstract: A system for delivering a guidewire through a heart valve comprises a delivery catheter configured to pass through a blood flow pathway of a heart, an inner catheter having an inner lumen, a guidewire configured to pass through the inner lumen of the inner catheter, and a positioning device crimped onto an outer surface of the inner catheter. wherein. The delivery catheter is configured to receive the inner catheter, guidewire, and positioning device and is configured to prevent expansion of the positioning device. The positioning device is configured to expand upon removal from the delivery catheter.

Abstract: A method comprises anchoring a first suture to a first papillary muscle, anchoring the first suture to a ventricle wall, and cinching the first suture to cause the first papillary muscle to move closer to the ventricle wall.

Abstract: A heart valve repair system includes an implantable device and a connector. The implantable device is configured to attach to at least two leaflets of a native heart valve of a patient and hold the at least two leaflets in a relatively fixed position. The connector is separate from the implantable device and includes first and second tissue anchors. The connector is configured to be attached to the at least two leaflets of the native valve when the at least two leaflets are held by the implantable device in the relatively fixed position. The implantable device is configured to be detached from the at least two leaflets and removed from the patient with the connector remaining attached to the at least two leaflets.

Abstract: Described herein are artificial valves that have a frame and leaflets that grow or expand with a patient. Upon placing the valve inside the patient, the valve expands as the annulus of the patient expands. The frame of the valve is configured to expand which in turn causes the leaflets to expand (e.g., to grow). The valve includes a thin undulating wire embedded inside the leaflets. As the annulus of the patient grows, the frame expands, and as the frame expands, the leaflets grow. The growth or expansion of the leaflets is configured so that the valve continues to operate properly (e.g., the leaflets continue to coapt) with expansion of the annulus. The change in size of the valve can be configured to accommodate changes in size of the annulus from an infant or child to an adult.

Abstract: A double heart valve anchoring system can include a first anchor having at least a portion configured to be secured within a first trans-septal opening in an interventricular septum, a tricuspid valve device coupled to the first anchor, and a mitral valve device coupled to the first anchor.

Abstract: A compliance restoration device includes a compliance balloon lumen, a chamber support structure disposed in the compliance balloon lumen and configured to expand to support an expanded volume of the compliance balloon lumen, and a spring assembly configured to cause the chamber support structure to expand by applying a force on a first end of the chamber support structure.

Abstract: A compliance restoration device includes a compliance balloon lumen, a chamber support structure disposed in the compliance balloon lumen and configured to expand to support an expanded volume of the compliance balloon lumen, and a spring assembly configured to cause the chamber support structure to expand by applying a force on a first end of the chamber support structure.