Abstract: A display substrate is provided, including: a base substrate; and a first electrode, a first light-emitting layer, a first hole blocking layer, a first electron transport layer, an electron injection layer, a second electrode, an optical extraction layer, a protective layer and an encapsulation layer sequentially arranged in a direction away from the base substrate. A refractive index of a material of the optical extraction layer is greater than that of a material of the protective layer, and the refractive index of the material of the protective layer is greater than that of a material of the second electrode.

Abstract: Provided are a display panel and a manufacturing method thereof and a display device. The display panel includes: a base substrate; a pixel defining layer including first openings defining sub-pixels; an encapsulation layer; and a light modulation layer. The light modulation layer is configured such that light from each of at least one sub-pixel propagates along a direction away from the base substrate after total reflection upon incidence on an interface between the first light modulation portion in a corresponding second opening and the first light modulation sub-layer. The display panel satisfies at least one of a first condition or a second condition. The first condition is that at least a part of edge of the first orthographic projection has a recess. The second condition is that at least a part of edge of the second orthogonal projection has at least one of a recess or a protrusion.

Abstract: A display substrate is provided, including: a base substrate and a first electrode, a first light-emitting layer, a first hole blocking layer, a first electron transport layer, an electron injection layer, a second electrode, an optical extraction layer, a protective layer, and an encapsulation layer that are sequentially arranged on the base substrate in a direction away from the base substrate. A refractive index of a material of the optical extraction layer is greater than a refractive index of a material of the encapsulation layer, and the refractive index of the material of the encapsulation layer is greater than a refractive index of a material of the second electrode.

Abstract: Provided are a display substrate and a display device. The display substrate includes: a base substrate; a first electrode; a light-emitting layer; a second electrode; an optical extraction layer; a protective layer; an encapsulation layer including a first intercalation layer and a second intercalation layer The color deviation adjustment layer of display substrate is configured to adjust color deviation of display substrate, so that the color deviation has a maximum value at observation angle in range of 0 to 90 degrees. The color deviation adjustment layer includes a first intercalation layer and a second intercalation layer located in the encapsulation layer. The color deviation adjustment layer also includes one of a film layer taken from the encapsulation layer except for the first intercalation layer and the second intercalation layer, the second electrode, the optical extraction layer, and the protective layer.

Abstract: A display baseplate and a display panel related to the technical field of display. The display baseplate includes a substrate; a pixel definition layer located on the substrate, wherein the pixel definition layer includes a partition part portion and a plurality of first openings, the partition part comprises a plurality of second openings, and depths of the plurality of first openings along a direction perpendicular to a plane where the substrate is located are greater than depths of the plurality of second openings along the direction perpendicular to the plane where the substrate is located; a plurality of light-emitting units each including a light-emitting functional layer, each first opening is provided with one of the light-emitting functional layers, and at least part of the second openings are provided with the light-emitting functional layers.

Abstract: A light-emitting device includes a first electrode; a second electrode; N light-emitting units stacked between the first electrode and the second electrode; and a connection layer disposed between any two adjacent light-emitting units. A peak of an intrinsic spectrum of at least part of light-emitting units is in a range from 400 nm to 480 nm. A sum of peaks of intrinsic spectra of the N light-emitting units is in a range from N×400 nm to N×480 nm; N?2, and N is a positive integer. A difference between a color coordinate y value of the light-emitting device under a blue image at a preset viewing angle that is in a range from 60° to 75° and a color coordinate y value of the light-emitting device under the blue image at a viewing angle of 0° is in a range from 0 to 0.07.

Abstract: A display substrate has an active area and a frame region located at at least one side of the active area. The display substrate includes a substrate, pixel units, at least one blocking dam and a first encapsulation layer. The pixel units is disposed on the substrate and located in the active area. The at least one blocking dam is disposed on the substrate and located in the frame area. The at least one blocking dam is provided with at least one groove on a surface thereof facing away from the substrate, a depth direction of the at least one groove is perpendicular to the substrate, and an extending direction of the at least one groove is substantially the same as an extending direction of the blocking dam provided with the at least one groove. The first encapsulation layer covers the at least one blocking dam.

Abstract: Provided are a display panel and a manufacturing method thereof and a display device. The display panel includes: a base substrate; a pixel defining layer including first openings defining sub-pixels; an encapsulation layer; and a light modulation layer. The light modulation layer is configured such that light from each of at least one sub-pixel propagates along a direction away from the base substrate after total reflection upon incidence on an interface between the first light modulation portion in a corresponding second opening and the first light modulation sub-layer. The display panel satisfies at least one of a first condition or a second condition. The first condition is that at least a part of edge of the first orthographic projection has a recess. The second condition is that at least a part of edge of the second orthogonal projection has at least one of a recess or a protrusion.

Abstract: A display substrate has an active area and a frame region located at least one side of the active area. The display substrate includes a substrate, pixel units, at least one blocking dam and a first encapsulation layer. The pixel units is disposed on the substrate and located in the active area. The at least one blocking dam is disposed on the substrate and located in the frame area. The at least one blocking dam is provided with at least one groove on a surface thereof facing away from the substrate, a depth direction of the at least one groove is perpendicular to the substrate, and an extending direction of the at least one groove is substantially the same as an extending direction of the blocking dam provided with the at least one groove. The first encapsulation layer covers the at least one blocking dam.

Abstract: A pixel circuit, a pixel driving method and a display device are provided. The pixel circuit includes a light-emitting element, a driving unit, a light-emitting control unit, a driving control unit, an energy storage unit, a first reset unit and a second reset unit, the first reset unit is configured to write a first voltage output by a first voltage line into a first terminal of the driving unit under control of the reset control line; the second reset unit is configured to write an initial voltage output by an initial voltage line into a control terminal of the driving unit under control of the reset control line; the driving unit is configured to drive the light-emitting element to emit light under control of the control terminal of the driving unit.

Abstract: Embodiments of the present disclosure provide a pixel circuit, a driving method thereof, and a display panel. The pixel circuit comprises: a light-emitting element; a driving sub-circuit configured to generate a current for driving the light-emitting element to emit light; and a first and a second light emission controlling sub-circuit, configured to supply the current for driving the light-emitting element to emit light to a first terminal of the light-emitting element under a control of a first controlling signal, respectively; a driving controlling sub-circuit configured to provide a data signal to the driving sub-circuit under a control of a second controlling signal; and the resetting sub-circuit configured to reset the driving sub-circuit, the first terminal of the light-emitting element, and a second node with a first voltage, under a control of a first resetting signal and a second resetting signal.

Abstract: Embodiments of the present disclosure provide a pixel circuit, a driving method thereof, and a display panel. The pixel circuit comprises: a light-emitting element; a driving sub-circuit configured to generate a current for driving the light-emitting element to emit light; and a first and a second light emission controlling sub-circuit, configured to supply the current for driving the light-emitting element to emit light to a first terminal of the light-emitting element under a control of a first controlling signal, respectively; a driving controlling sub-circuit configured to provide a data signal to the driving sub-circuit under a control of a second controlling signal; and the resetting sub-circuit configured to reset the driving sub-circuit, the first terminal of the light-emitting element, and a second node with a first voltage, under a control of a first resetting signal and a second resetting signal.

Abstract: A pixel circuit, a pixel driving method and a display device are provided. The pixel circuit includes a light-emitting element, a driving unit, a light-emitting control unit, a driving control unit, an energy storage unit, a first reset unit and a second reset unit, the first reset unit is configured to write a first voltage output by a first voltage line into a first terminal of the driving unit under control of the reset control line; the second reset unit is configured to write an initial voltage output by an initial voltage line into a control terminal of the driving unit under control of the reset control line; the driving unit is configured to drive the light-emitting element to emit light under control of the control terminal of the driving unit.

Abstract: A class of novel non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-?B activity including obesity, diabetes, inflammatory and immune diseases, and have the structure of formula (I) or (II): including a stereoisomer thereof, a tautomer thereof, a prodrug thereof, or a pharmaceutically acceptable salt thereof, where Q is selected from N, O, and S; Y is aryl or heteroaryl; Z is H, C2-6alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, halo, or alkoxy; and A, B, R, Ra, Rb, Rc and Rd are defined herein. Also provided are pharmaceutical compositions and methods of treating obesity, diabetes and inflammatory or immune associated diseases comprising said compounds.

Abstract: A class of novel non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-?B activity including obesity, diabetes, inflammatory and immune diseases, and have the structure of formula (I) or (II): including a stereoisomer thereof, a tautomer thereof, a prodrug thereof, or a pharmaceutically acceptable salt thereof, where Q is selected from N, O, and S; Y is aryl or heteroaryl; Z is H, C2-6alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, halo, or alkoxy; and A, B, R, Ra, Rb, Rc and Rd are defined herein. Also provided are pharmaceutical compositions and methods of treating obesity, diabetes and inflammatory or immune associated diseases comprising said compounds.

Abstract: A class of novel non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-?B activity including obesity, diabetes, inflammatory and immune diseases, and have the structure of formula (I) or (II): including a stereoisomer thereof, a tautomer thereof, a prodrug thereof, or a pharmaceutically acceptable salt thereof, where Q is selected from N, O, and S; Y is aryl or heteroaryl; Z is H, C2-6alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, halo, or alkoxy; and A, B, R, Ra, Rb, Rc and Rd are defined herein. Also provided are pharmaceutical compositions and methods of treating obesity, diabetes and inflammatory or immune associated diseases comprising said compounds.

Abstract: Novel non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-?B activity including obesity, diabetes, inflammatory and immune diseases, and have the structure of formula (I) or stereoisomers or prodrugs or pharmaceutically acceptable salts thereof, wherein B, J, K, Z, R, Ra, Rb, Rc, Rd, Rq, Rw, m and n are defined herein. Also provided are pharmaceutical compositions and methods of treating obesity, diabetes and inflammatory or immune associated diseases comprising said compounds.

Abstract: A class of novel non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-?B activity including obesity, diabetes, inflammatory and immune diseases, and have the structure of formula (I) or (II): including a stereoisomer thereof, a tautomer thereof, a prodrug thereof, or a pharmaceutically acceptable salt thereof, where Q is selected from N, O, and S; Y is aryl or heteroaryl; Z is H, C2-6alkyl, cycloalkyl, heterocycloalkyl, aryl, heteroaryl, halo, or alkoxy; and A, B, R, Ra, Rb, Rc and Rd are defined herein. Also provided are pharmaceutical compositions and methods of treating obesity, diabetes and inflammatory or immune associated diseases comprising said compounds.

Abstract: A class of novel non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-?B activity including obesity, diabetes, inflammatory and immune diseases, and have the structure of formula (I): where X is S, O or N; Z is —T—COOR1 or —T—COR1; and T, R, R1, Ra, Rb, Rc, Rd, Z, A and B are defined herein. Also provided are pharmaceutical compositions and methods of treating obesity, diabetes and inflammatory or immune associated diseases comprising said compounds.

Abstract: The present invention relates to new class of non-steroidal compounds which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-?B activity including obesity, diabetes, inflammatory- and immune-associated diseases, and have the structure including all stereoisomers thereof, tautomers thereof, or a prodrug thereof, or a pharmaceutically acceptable salt thereof, wherein X is selected from N, O, and S; Y is N or CR6; Z is a ring; and where R, Ra, Rb, Rc, Rd, R1, R2, R3, R4, and R5 are as defined herein. Also provided are pharmaceutical compositions and methods of treating obesity, diabetes and inflammatory or immune associated diseases comprising said compounds.